Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation

Journal article


Draganidis, Dimitrios, Jamurtas, A, Stampoulis, Theodoros, Laschou, Vasiliki C., Deli, Chariklia K., Georgakouli, Kalliopi, Papanikolaou, Konstantinos, Chatzinikolaou, A, Michalopoulou, Maria, Papadopoulos, Constantinos, Tsimeas, Panagiotis, Chondrogianni, Niki, Koutedakis, Yiannis, Karagounis, Leonidas and Fatouros, i. (2018). Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation. Nutrients. 10(5), p. Article 566. https://doi.org/10.3390/nu10050566
AuthorsDraganidis, Dimitrios, Jamurtas, A, Stampoulis, Theodoros, Laschou, Vasiliki C., Deli, Chariklia K., Georgakouli, Kalliopi, Papanikolaou, Konstantinos, Chatzinikolaou, A, Michalopoulou, Maria, Papadopoulos, Constantinos, Tsimeas, Panagiotis, Chondrogianni, Niki, Koutedakis, Yiannis, Karagounis, Leonidas and Fatouros, i
Abstract

The development of chronic, low-grade systemic inflammation in the elderly (inflammaging) has been associated with increased incidence of chronic diseases, geriatric syndromes, and functional impairments. The aim of this study was to examine differences in habitual physical activity (PA), dietary intake patterns, and musculoskeletal performance among community-dwelling elderly men with low and elevated systemic inflammation. Nonsarcopenic older men free of chronic diseases were grouped as ‘low’ (LSI: n = 17; 68.2 ± 2.6 years; hs-CRP: <1 mg/L) or ‘elevated’ (ESI: n = 17; 68.7 ± 3.0 years; hs-CRP: >1 mg/L) systemic inflammation according to their serum levels of high-sensitivity CRP (hs-CRP). All participants were assessed for body composition via Dual Emission X-ray Absorptiometry (DEXA), physical performance using the Short Physical Performance Battery (SPPB) and handgrip strength, daily PA using accelerometry, and daily macro- and micronutrient intake. ESI was characterized by a 2-fold greater hs-CRP value than LSI (p < 0.01). The two groups were comparable in terms of body composition, but LSI displayed higher physical performance (p < 0.05), daily PA (step count/day and time at moderate-to-vigorous PA (MVPA) were greater by 30% and 42%, respectively, p < 0.05), and daily intake of the antioxidant vitamins A (6590.7 vs. 4701.8 IU/day, p < 0.05), C (120.0 vs. 77.3 mg/day, p < 0.05), and E (10.0 vs. 7.5 mg/day, p < 0.05) compared to ESI. Moreover, daily intake of vitamin A was inversely correlated with levels of hs-CRP (r = −0.39, p = 0.035). These results provide evidence that elderly men characterized by low levels of systemic inflammation are more physically active, spend more time in MVPA, and receive higher amounts of antioxidant vitamins compared to those with increased systemic inflammation.

Keywordsaging; chronic low-grade systemic inflammation; physical activity; nutrition; physical performance; chronic diseases
Year2018
JournalNutrients
Journal citation10 (5), p. Article 566
PublisherMultidisciplinary Digital Publishing Institute (MDPI AG)
ISSN2072-6643
Digital Object Identifier (DOI)https://doi.org/10.3390/nu10050566
PubMed ID29734698
Scopus EID2-s2.0-85046644612
PubMed Central IDPMC5986446
Open accessPublished as ‘gold’ (paid) open access
Page range1-16
FunderGeneral Secretariat for Research and Technology (GSRT)
Hellenic Foundation for Research and Innovation (HFRI)
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online04 May 2018
Publication process dates
Accepted01 May 2018
Deposited21 Nov 2023
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