Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation

Journal article


Draganidis, Dimitrios, Jamurtas, A, Stampoulis, Theodoros, Laschou, Vasiliki C., Deli, Chariklia K., Georgakouli, Kalliopi, Papanikolaou, Konstantinos, Chatzinikolaou, A, Michalopoulou, Maria, Papadopoulos, Constantinos, Tsimeas, Panagiotis, Chondrogianni, Niki, Koutedakis, Yiannis, Karagounis, Leonidas and Fatouros, i. (2018). Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation. Nutrients. 10(5), p. Article 566. https://doi.org/10.3390/nu10050566
AuthorsDraganidis, Dimitrios, Jamurtas, A, Stampoulis, Theodoros, Laschou, Vasiliki C., Deli, Chariklia K., Georgakouli, Kalliopi, Papanikolaou, Konstantinos, Chatzinikolaou, A, Michalopoulou, Maria, Papadopoulos, Constantinos, Tsimeas, Panagiotis, Chondrogianni, Niki, Koutedakis, Yiannis, Karagounis, Leonidas and Fatouros, i
Abstract

The development of chronic, low-grade systemic inflammation in the elderly (inflammaging) has been associated with increased incidence of chronic diseases, geriatric syndromes, and functional impairments. The aim of this study was to examine differences in habitual physical activity (PA), dietary intake patterns, and musculoskeletal performance among community-dwelling elderly men with low and elevated systemic inflammation. Nonsarcopenic older men free of chronic diseases were grouped as ‘low’ (LSI: n = 17; 68.2 ± 2.6 years; hs-CRP: <1 mg/L) or ‘elevated’ (ESI: n = 17; 68.7 ± 3.0 years; hs-CRP: >1 mg/L) systemic inflammation according to their serum levels of high-sensitivity CRP (hs-CRP). All participants were assessed for body composition via Dual Emission X-ray Absorptiometry (DEXA), physical performance using the Short Physical Performance Battery (SPPB) and handgrip strength, daily PA using accelerometry, and daily macro- and micronutrient intake. ESI was characterized by a 2-fold greater hs-CRP value than LSI (p < 0.01). The two groups were comparable in terms of body composition, but LSI displayed higher physical performance (p < 0.05), daily PA (step count/day and time at moderate-to-vigorous PA (MVPA) were greater by 30% and 42%, respectively, p < 0.05), and daily intake of the antioxidant vitamins A (6590.7 vs. 4701.8 IU/day, p < 0.05), C (120.0 vs. 77.3 mg/day, p < 0.05), and E (10.0 vs. 7.5 mg/day, p < 0.05) compared to ESI. Moreover, daily intake of vitamin A was inversely correlated with levels of hs-CRP (r = −0.39, p = 0.035). These results provide evidence that elderly men characterized by low levels of systemic inflammation are more physically active, spend more time in MVPA, and receive higher amounts of antioxidant vitamins compared to those with increased systemic inflammation.

Keywordsaging; chronic low-grade systemic inflammation; physical activity; nutrition; physical performance; chronic diseases
Year2018
JournalNutrients
Journal citation10 (5), p. Article 566
PublisherMultidisciplinary Digital Publishing Institute (MDPI AG)
ISSN2072-6643
Digital Object Identifier (DOI)https://doi.org/10.3390/nu10050566
PubMed ID29734698
Scopus EID2-s2.0-85046644612
PubMed Central IDPMC5986446
Open accessPublished as ‘gold’ (paid) open access
Page range1-16
FunderGeneral Secretariat for Research and Technology (GSRT)
Hellenic Foundation for Research and Innovation (HFRI)
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online04 May 2018
Publication process dates
Accepted01 May 2018
Deposited21 Nov 2023
Permalink -

https://acuresearchbank.acu.edu.au/item/8zz7w/disparate-habitual-physical-activity-and-dietary-intake-profiles-of-elderly-men-with-low-and-elevated-systemic-inflammation

Download files


Publisher's version
  • 15
    total views
  • 8
    total downloads
  • 1
    views this month
  • 2
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Skeletal muscle myostatin mRNA expression is upregulated in aged human adults with excess adiposity but is not associated with insulin resistance and ageing
Wilhelmsen, Andrew, Stephens, F, Bennett, Andrew J., Karagounis, Leonidas, Jones, Simon W. and Tsintzas, Kostas. (2023). Skeletal muscle myostatin mRNA expression is upregulated in aged human adults with excess adiposity but is not associated with insulin resistance and ageing. GeroScience. 46(2), pp. 2033-2049. https://doi.org/10.1007/s11357-023-00956-6
A meta-analysis comparing the effectiveness of alternate day fasting, the 5:2 diet, and time-restricted eating for weight loss
Elortegui Pascual, Paloma, Rolands, Maryann R., Eldridge, Alison L., Kassis, Amira, Mainardi, Fabio, Lê, Kim-Anne, Karagounis, Leonidas G., Gut, Philipp and Varady, Krista A.. (2023). A meta-analysis comparing the effectiveness of alternate day fasting, the 5:2 diet, and time-restricted eating for weight loss. Obesity. 31(Supp. 1), pp. 9-21. https://doi.org/10.1002/oby.23568
A randomized controlled clinical trial in healthy older adults to determine efficacy of glycine and n-acetylcysteine supplementation on glutathione redox status and oxidative damage
Lizzo, Giulia, Migliavacca, Eugenia, Lamers, Daniela, Frézal, Adrien, Corthesy, John, Vinyes-Parès, Gerard, Bosco, Nabil, Karagounis, Leonidas, Hövelmann, Ulrike, Heise, Tim, Von Eynatten, Maximilian and Gut, Philipp. (2022). A randomized controlled clinical trial in healthy older adults to determine efficacy of glycine and n-acetylcysteine supplementation on glutathione redox status and oxidative damage. Frontiers in Aging. 3, p. Article 852569. https://doi.org/10.3389/fragi.2022.852569
Impact of moderate dietary protein restriction on glucose homeostasis in a model of estrogen deficiency
Fournier, Carole, Karagounis, Leonidas G., Sacco, Sandra M., Horcajada, Marie-Noelle, Decaens, Thomas, Offord, Elizabeth A., Bouzakri, Karim and Ammann, Patrick. (2022). Impact of moderate dietary protein restriction on glucose homeostasis in a model of estrogen deficiency. Journal of Nutritional Biochemistry. 102, p. Article 108952. https://doi.org/10.1016/j.jnutbio.2022.108952
Low-grade systemic inflammation interferes with anabolic and catabolic characteristics of the aged human skeletal muscle
Draganidis, Dimitrios, Jamurtas, Athanasios Z., Chondrogianni, Niki, Mastorakos, Georgios, Jung, Tobias, Grune, Tilman, Papadopoulos, Constantinos, Papanikolaou, Konstantinos, Papassotiriou, Ioannis, Papaevgeniou, Nikoletta, Poulios, Athanasios, Batrakoulis, Alexios, Deli, Chariklia K., Georgakouli, Kalliopi, Chatzinikolaou, Athanasios, Karagounis, Leonidas G. and Fatouros, Ioannis G.. (2021). Low-grade systemic inflammation interferes with anabolic and catabolic characteristics of the aged human skeletal muscle. Oxidative Medicine and Cellular Longevity. 2021, p. Article 8376915. https://doi.org/10.1155/2021/8376915
Unacylated ghrelin, leptin, and appetite display diurnal rhythmicity in lean Adults
Templeman, Iain, Smith, Harry A., Walhin, Jean-Philippe, Middleton, Benita, Gonzalez, Javier T., Karagounis, Leonidas G., Johnston, Jonathan D. and Betts, James A.. (2021). Unacylated ghrelin, leptin, and appetite display diurnal rhythmicity in lean Adults. Journal of Applied Physiology. 130(5), pp. 1534-1543. https://doi.org/10.1152/japplphysiol.00920.2020
Systemic and metabolic signature of sarcopenia in community-dwelling older adults
Lu, Yanxia, Karagounis, Leonidas G., Ng, Tze Pin, Carre, Christophe, Narang, Vipin, Wong, Glenn, Tan, Crystal Tze Ying, Nyunt, Ma Shwe Zin, Gao, Qi, Abel, Brian, Poidinger, Michael, Fulop, Tamas, Bosco, Nabil and Larbi, Anis. (2020). Systemic and metabolic signature of sarcopenia in community-dwelling older adults. Journals of Gerontology: Series A Biological Sciences and Medical Sciences. 75(2), pp. 309-317. https://doi.org/10.1093/gerona/glz001
Ingestion of a pre-bedtime protein containing beverage prevents overnight induced negative whole body protein balance in healthy middle-aged men : A randomized trial
Karagounis, Leonidas G., Beaumont, Maurice, Donato-Capel, Laurence, Godin, Jean-Philippe, Kapp, Anne-France, Draganidis, Dimitrios, Pinaud, Stéphane, Vuichoud, Jacques, Shevlyakova, Maya, Rade-Kukic, Koraljka and Breuillé, Denis. (2019). Ingestion of a pre-bedtime protein containing beverage prevents overnight induced negative whole body protein balance in healthy middle-aged men : A randomized trial. Frontiers in Nutrition. 6, p. Article 181. https://doi.org/10.3389/fnut.2019.00181
Longitudinal association of dietary protein intake in infancy and adiposity throughout childhood
Jen, Vincent, Braun, Kim V. E., Karagounis, Leonidas G., Nguyen, Anh N., Jaddoe, Vincent W. V., Schoufour, Josje D., Franco, Oscar H. and Voortman, Trudy. (2019). Longitudinal association of dietary protein intake in infancy and adiposity throughout childhood. Clinical Nutrition. 38(3), pp. 1296-1302. https://doi.org/10.1016/j.clnu.2018.05.013
Post-game high protein intake may improve recovery of football-specific performance during a congested game fixture : Results from the PRO-FOOTBALL study
Poulios, Athanasios, Fatouros, Ioannis G., Mohr, Magni, Draganidis, Dimitrios, Deli, Chariklia K., Papanikolaou, Konstantinos, Sovatzidis, Apostolos, Nakopoulou, Theofano, Ermidis, Georgios, Tzatzakis, Theofanis, Laschou, Vasiliki C., Georgakouli, Kalliopi, Koulouris, Agisilaos, Tsimeas, Panagiotis, Chatzinikolaou, Athanasios, Karagounis, Leonidas G., Batsilas, Dimitrios, Krustrup, Peter and Jamurtas, Athanasios Z.. (2018). Post-game high protein intake may improve recovery of football-specific performance during a congested game fixture : Results from the PRO-FOOTBALL study. Nutrients. 10(4), p. Article 494. https://doi.org/10.3390/nu10040494
Dietary protein intake in school-age children and detailed measures of body composition : The Generation R Study
Jen, Vincent, Karagounis, Leonidas G., Jaddoe, Vincent W. V., Franco, Oscar H. and Voortman, Trudy. (2018). Dietary protein intake in school-age children and detailed measures of body composition : The Generation R Study. International Journal of Obesity. 42(10), pp. 1715-1723. https://doi.org/10.1038/s41366-018-0098-x
Protein intake at breakfast promotes a positive whole-body protein balance in a dose-response manner in healthy children : A randomized trial
Karagounis, Leonidas G., Volterman, Kimberly A., Breuillé, Denis, Offord, Elizabeth A., Emady-Azar, Shahram and Moore, Daniel R.. (2018). Protein intake at breakfast promotes a positive whole-body protein balance in a dose-response manner in healthy children : A randomized trial. The Journal of Nutrition. 148(5), pp. 729-737. https://doi.org/10.1093/jn/nxy026
Timing and pattern of postexercise protein ingestion affects whole-body protein balance in healthy children : A randomized trial
Volterman, Kimberly A., Moore, Daniel R., Breithaupt, Peter, Grathwohl, Dominik, Offord, Elizabeth A., Karagounis, Leonidas G. and Timmons, Brian W.. (2017). Timing and pattern of postexercise protein ingestion affects whole-body protein balance in healthy children : A randomized trial. Applied Physiology, Nutrition and Metabolism. 42(11), pp. 1142-1148. https://doi.org/10.1139/apnm-2017-0185
Protein ingestion preserves proteasome activity during intense aseptic inflammation and facilitates skeletal muscle recovery in humans
Draganidis, Dimitrios, Chondrogianni, Niki, Chatzinikolaou, Athanasios, Terzis, Gerasimos, Karagounis, Leonidas G., Sovatzidis, Apostolos, Avloniti, Alexandra, Lefaki, Maria, Protopapa, Maria, Deli, Chariklia K., Papanikolaou, Konstantinos, Jamurtas, Athanasios Z. and Fatouros, Ioannis G.. (2017). Protein ingestion preserves proteasome activity during intense aseptic inflammation and facilitates skeletal muscle recovery in humans. British Journal of Nutrition. 118(3), pp. 189-200. https://doi.org/10.1017/S0007114517001829
Amino acid composition of breast milk from urban Chinese mothers
Garcia-Rodenas, Clara L., Affolter, Michael, Vinyes-Parès, Gerard, De Castro, Carlos A., Karagounis, Leonidas G., Zhang, Yumei, Wang, Peiyu and Thakkar, Sagar K.. (2016). Amino acid composition of breast milk from urban Chinese mothers. Nutrients. 8(10), p. Article 606. https://doi.org/10.3390/nu8100606
Inflammaging and skeletal muscle : Can protein intake make a difference?
Draganidis, Dimitrios, Karagounis, Leonidas G., Athanailidis, Ioannis, Chatzinikolaou, Athanasios, Jamurtas, Athanasios Z. and Fatouros, Ioannis G.. (2016). Inflammaging and skeletal muscle : Can protein intake make a difference? The Journal of Nutrition. 146(10), pp. 1940-1952. https://doi.org/10.3945/jn.116.230912