A potential role for photobiomodulation therapy in disease treatment and prevention in the era of COVID-19

Journal article


Liebert, Ann, Bicknell, Brian, Markman, Wayne and Kiat, Hosen. (2020). A potential role for photobiomodulation therapy in disease treatment and prevention in the era of COVID-19. Aging and Disease. 11(6), pp. 1352-1362. https://doi.org/10.14336/AD.2020.0901
AuthorsLiebert, Ann, Bicknell, Brian, Markman, Wayne and Kiat, Hosen
Abstract

COVID-19 is an evolving pandemic that has far reaching global effects, with a combination of factors that makes the virus difficult to contain. The symptoms of infection can be devastating or at the least very debilitating for vulnerable individuals. It is clear that the elderly are at most risk of the adverse impacts of the virus, including hospitalization and death. Others at risk are those with comorbidities such as cardiovascular disease and metabolic conditions and those with a hyper-excitable immune response. Treatment options for those with acute responses to the virus are limited and there is an urgent need for potential strategies that can mitigate these severe effects. One potential avenue for treatment that has not been explored is the microbiome gut/lung axis. In addition to those severely affected by their acute reaction to the virus, there is also a need for treatment options for those that are slow to recover from the effects of the infection and also those who have been adversely affected by the measures put in place to arrest the spread of the virus. One potential treatment option is photobiomodulation (PBM) therapy. PBM has been shown over many years to be a safe, effective, non-invasive and easily deployed adjunctive treatment option for inflammatory conditions, pain, tissue healing and cellular energy. We have also recently demonstrated the effectiveness of PBM to alter the gut microbiome. PBM therapy is worthy of consideration as a potential treatment for those most vulnerable to COVID-19, such as the elderly and those with comorbidities. The treatment may potentially be advantageous for those infected with the virus, those who have a slow recovery from the effects of the virus and those who have been denied their normal exercise/rehabilitation programs due to the isolation restrictions that have been imposed to control the COVID-19 pandemic.

KeywordsCOVID-19; photobiomodulation; immunomodulation; mitochondrial dysfunction; microbiome
Year01 Jan 2020
JournalAging and Disease
Journal citation11 (6), pp. 1352-1362
PublisherJKL International
ISSN2152-5250
Digital Object Identifier (DOI)https://doi.org/10.14336/AD.2020.0901
Web address (URL)https://www.aginganddisease.org/EN/10.14336/AD.2020.0901
Open accessOpen access
Research or scholarlyResearch
Page range1352-1362
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online01 Dec 2020
Publication process dates
Accepted01 Sep 2020
Deposited19 Nov 2024
Additional information

© 2020 Liebert A. et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Place of publicationUnited States
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