Cost-effectiveness of constraint-induced movement therapy implementation in neurorehabilitation : the ACTIveARM project

Journal article


Christie, Lauren J., Fearn, Nicola, McCluskey, Annie, Lovarini, Meryl, Rendell, Reem and Pearce, Alison. (2022). Cost-effectiveness of constraint-induced movement therapy implementation in neurorehabilitation : the ACTIveARM project. Pharmacoeconomics - Open. 6(3), pp. 437-450. https://doi.org/10.1007/s41669-022-00323-9
AuthorsChristie, Lauren J., Fearn, Nicola, McCluskey, Annie, Lovarini, Meryl, Rendell, Reem and Pearce, Alison
Abstract

Background
Constraint-induced movement therapy (CIMT) is a recommended intervention for improving arm recovery following stroke and traumatic brain injury; however, delivery in practice remains rare.

Purpose
The aim of this study was to investigate the costs and cost effectiveness of CIMT delivery, and the use of a CIMT implementation package designed to improve CIMT uptake and delivery by therapists in Sydney, Australia.

Methods
This economic evaluation was conducted with a subset of CIMT programmes (n = 20) delivered by neurological rehabilitation teams at five varied hospitals within a mixed methods implementation study (ACTIveARM). The costs of delivering the CIMT implementation package and publicly funded CIMT were calculated using a bottom-up approach. A cost-effectiveness analysis was conducted, using decision analytic modelling. We compared the uptake and outcomes of people who received CIMT from health services that had received a CIMT implementation package, with those receiving standard upper limb therapy. An Australian health care system perspective was used in the model, over a 3-week time horizon (the average timeframe of a CIMT programme). All costs were calculated in Australian dollars (AUD). Inputs were derived from the ACTIveARM study and relevant literature. The Action Research Arm Test was used to measure arm outcomes. Sensitivity analyses assessed the impact of improving CIMT uptake, scale-up of the implementation package and resource adjustment, including a ‘best-case’ scenario analysis.

Results
The total cost of delivering the implementation package to nine teams across five hospitals was $110,336.43 AUD over 18 months. The mean cost of delivering an individual CIMT programme was $1233.38 AUD per participant, and $936.03 AUD per participant for group-based programmes. The incremental cost-effectiveness ratio (ICER) of individual CIMT programmes was $8052 AUD per additional person achieving meaningful improvement in arm function, and $6045 AUD for group-based CIMT. The ICER was most sensitive to reductions in staffing costs. In the ‘best-case’ scenario, the ICER for both individual and group-based CIMT was $245 AUD per additional person gaining a meaningful change in function.

Conclusion
Therapists improved CIMT uptake and delivery with the support of an implementation package, however cost effectiveness was unclear.

Keywordsstroke ; traumatic brain injury ; disability; arm impairment ; constraint-induced movement therapy (CIMT)
Year01 Jan 2022
JournalPharmacoeconomics - Open
Journal citation6 (3), pp. 437-450
PublisherAdis International Ltd
ISSN2509-4262
Digital Object Identifier (DOI)https://doi.org/10.1007/s41669-022-00323-9
Web address (URL)https://link.springer.com/article/10.1007/s41669-022-00323-9
Open accessOpen access
Research or scholarlyResearch
Page range437-450
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online22 Mar 2022
Publication process dates
Accepted17 Jan 2022
Deposited06 Dec 2024
Supplemental file
License
File Access Level
Open
Additional information

© Crown 2022

This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

Funding: The project was funded by the New South Wales Ministry of Health Translational Research Grants Scheme (TRGS) (project number 28).

Place of publicationNew Zealand
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