Diagnosing and managing patients with heart failure with preserved ejection fraction : A consensus survey

Journal article


Austin, Rosalynn, Khair, Eva, Blakeman, Thomas, Hossain, Muhammad Zakir, Sowden, Emma, Chew-Graham, Carolyn A, Forsyth, Faye, Deaton, Christi, Optimise HFpEF Investigators and Wellwood, Ian*. (2024). Diagnosing and managing patients with heart failure with preserved ejection fraction : A consensus survey. BMJ Open. 14(12), p. Article e092993. https://doi.org/10.1136/bmjopen-2024-092993
AuthorsAustin, Rosalynn, Khair, Eva, Blakeman, Thomas, Hossain, Muhammad Zakir, Sowden, Emma, Chew-Graham, Carolyn A, Forsyth, Faye, Deaton, Christi, Optimise HFpEF Investigators and Wellwood, Ian*
Abstract

Aim
As heart failure (HF) with preserved ejection fraction (HFpEF) prevalence increases, it remains frequently underdiagnosed and poorly managed. Recent positive pharmacological trials have increased interest in HFpEF but challenges of diagnosis and management remain. The survey aim was to examine consensus between primary and secondary care providers regarding HFpEF diagnosis and management.

Methods
As part of a larger programme of work, survey questions were developed in an online format and piloted with healthcare providers (HCPs). The survey link was distributed via professional networks and social media. Analysis included frequencies of responses, comparison by main professional groups and thematic analysis free-text responses. A virtual workshop of HCPs was conducted to discuss and refine survey findings.

Results
HCPs (n=66) across the UK participated: 19 general practitioners (GPs), 20 HF specialist nurses (HFSN), 17 cardiologists and 10 others. Consensus was high (92%) that diagnosing the type of HF was very important and most favoured inclusion of HFpEF in Quality Outcome Framework indicators. No clear consensus was reached that ongoing management should be in primary care (47.5% of GPs, 35% of HFSN and 31.3% of cardiologists ‘somewhat agreed’). Opinions differed between GPs (52.3)% and specialists (HFSN 80% and cardiologists 81.3%) for practice nurses to be upskilled and assume HFpEF management. No HCPs reported any level of disagreement for HFSN management of HFpEF. Free-text comments highlighted resource barriers to HFpEF diagnosis and management and confirmed the need to develop better HFpEF services.

Conclusions
Consensus was reached regarding importance of diagnosing HFpEF, but agreement on methods and responsibilities for diagnosis and management varied. Free-text comments identified HCPs concerns related to overwhelmed primary and secondary care services and lack of sufficient resources to meet existing patient demands. Creation of collaborative care pathways is needed to support the increasing number of older patients with HFpEF.

Trial registration number
ClinicalTrials. gov (reference number: NCT03617848).

Year2024
JournalBMJ Open
Journal citation14 (12), p. Article e092993
PublisherBMJ Publishing Group
ISSN2044-6055
Digital Object Identifier (DOI)https://doi.org/10.1136/bmjopen-2024-092993
PubMed ID39806710
Scopus EID2-s2.0-85214120176
PubMed Central IDPMC11667415
Open accessPublished as ‘gold’ (paid) open access
Page range1-13
FunderSchool for Primary Care Research (SPCR), National Institute for Health Research
Biomedical Research Centre (BRC), National Institute for Health Research
Addenbrooke’s Charitable Trust
British Heart Foundation
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online20 Dec 2024
Publication process dates
Accepted25 Nov 2024
Deposited04 Apr 2025
Grant ID384
BRC-1215- 20014
Additional information

*Ian Wellwood is a member of the Optimise HFpEF Investigators.

OPTIMISE HFpEF Investigators and Collaborators: Dr Mollika Chakravorty, Dr Sophie Maclachlan, Dr Edward Kane, Dr Jessica Odone, Dr Natasha Thorley, Susana[FF1] Borja-Boluda, Dr Ian Wellwood, Dr Emma Sowden, Dr Thomas Blakeman, Professor Carolyn Chew-Graham, Dr Muhammed Hossain, John Sharpley, Dr Brain Gordon, Joanna Taffe, Aaron Long, Affan Aziz, Hannah Swayze, Heather Rutter, Dr Chris Schramm, Sine MacDonald, Dr Helena Papworth, Dr Julie Smith, Dr Craig Needs, Dr David Cronk, Dr Chris Newark, Dr Duncan Blake, Dr Alistair Brown, Dr Amman Basuita, Dr Emma Gayton, Dr Victoria Glover, Dr Robin Fox, Dr Jonathan Crawshaw, Dr Helen Ashdown, Dr Christine A’Court, Rachael Ayerst, Dr Basilio Hernandez-Diaz, Dr Kyle Knox, Dr Nick Wooding, Dr Shamila Wanninayake, Dr Christopher Keast, Dr Adam Jones, Dr Katherine Brown, Dr Matthew Gaw, Dr Nick Thomas, Dr Sharon Dixon and Dr Elisabetta Angeleri-Rand.

© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY (https://creativecommons.org/licenses/by/4.0/). Published by BMJ Group.

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