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Importance of clinical worsening of heart failure treated in the outpatient setting: Evidence from the prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial (PARADIGM-HF)
Okumura, Naoki Jhund, Pardeep Gong, Jianjian Lefkowitz, Martin P. Rizkala, Adel R. Rouleau, Jean L. Shi, Victor C. Swedberg, Karl Zile, Michael R. Solomon, Scott
Okumura, Naoki
Jhund, Pardeep
Gong, Jianjian
Lefkowitz, Martin P.
Rizkala, Adel R.
Rouleau, Jean L.
Shi, Victor C.
Swedberg, Karl
Zile, Michael R.
Solomon, Scott
Abstract
Many episodes of worsening of heart failure (HF) are treated by increasing oral therapy or temporary intravenous treatment in the community or emergency department (ED), without hospital admission. We studied the frequency and prognostic importance of these episodes of worsening in the Prospective Comparison of ARNI (angiotensin-receptor-neprilysin inhibitor) with ACEI (angiotensin-converting enzyme inhibitor) to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial (PARADIGM-HF).
Keywords
emergency service, hospital, heart failure, hospitalization, mortality, neprilysin, sacubitril/valsartan
Date
2016
Type
Journal article
Journal
Circulation
Book
Volume
133
Issue
23
Page Range
2254-2262
Article Number
ACU Department
Collections
Relation URI
Source URL
Event URL
Open Access Status
Open access
License
File Access
Controlled