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Hospital admission for infection during early childhood influences developmental vulnerabilities at age 5 years
Kariuki, Maina Raudino, Alessandra Green, Melissa J. Laurens, Kristin R. Dean, Kimberlie Brinkman, Sally A. Lenroot, Rhoshel K. Liu, Enwu Harris, Felicity Luo, Luming
Kariuki, Maina
Raudino, Alessandra
Green, Melissa J.
Laurens, Kristin R.
Dean, Kimberlie
Brinkman, Sally A.
Lenroot, Rhoshel K.
Liu, Enwu
Harris, Felicity
Luo, Luming
Abstract
Aim: Childhood infectious diseases can be associated with later physical and psychological ill health, and the effects of this association may be evident during early childhood development. This study aimed to examine the effects of hospitalisation for early life infection on early childhood development. Methods: Hospital admission data for infection were obtained from the New South Wales Ministry of Health Admitted Patient Data Collection for 87 026 children, for whom the Australian Early Development Census ( AEDC ) was completed in their first year of formal schooling ( age approximately 5 years ). The AEDC provides estimates of each child's level of functioning on five domains of development spanning social and emotional skills, communication skills, numeracy and literacy and physical health. Multinomial logistic regressions were used to determine the relationship between exposure to hospital admissions for infectious disease prior to age 4 years and vulnerability on the AEDC. Models were adjusted for the effects of potential confounding factors related to the perinatal period, exposure to maltreatment and family characteristics. Results: Single and multiple hospitalisation( s ) for infections were consistently associated with increased likelihood of being developmentally vulnerable on all AEDC domains, with odds ratios ranging from 1.02 to 1.28, after adjustment for confounding factors. Conclusions: This study demonstrates a pervasive effect of early life infections that require hospital admission on multiple aspects of early child development, even after adjustment for potential confounding factors. Relatively, severe infection during early childhood constitutes a risk factor for developmental vulnerability by the time of entry to school.
Keywords
child, child development, hospitalised, infection, medical record linkage
Date
2016
Type
Journal article
Journal
Journal of Paediatrics and Child Health
Book
Volume
52
Issue
9
Page Range
882-888
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
Collections
Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled