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FRAX: Assessment of Fracture Risk
Kanis, John McCloskey, Eugene Harvey, Nicholas C. Leslie, William D.
Kanis, John
McCloskey, Eugene
Harvey, Nicholas C.
Leslie, William D.
Abstract
A major objective of fracture risk assessment is to enable the targeting of interventions to those at need and avoid unnecessary treatment in those at low risk of fracture. Several risk prediction models have been developed, but the most widely used is the Fracture Risk Assessment Tool (FRAX). FRAX is a computer‐based algorithm that is intended for primary care, calculates fracture probability from easily obtained clinical risk factors in men aged 40 years or more and postmenopausal women. Fracture probability is computed taking into account both the risk of fracture and the risk of death. The use of clinical risk factors alone provides a gradient of risk that lies between 1.4 and 2.1, depending upon age and the type of fracture predicted. FRAX should not be considered as a gold standard in patient assessment, but rather as a reference platform. FRAX has been recommended as a screening tool to detect osteoporosis.
Keywords
clinical risk factors, fracture probability, fracture risk assessment tool, gradient of risk, osteoporosis, primary care
Date
2019
Type
Book chapter
Journal
Book
Primer on the metabolic bone diseases and disorders of mineral metabolism
Volume
Issue
Page Range
331-339
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
Collections
Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled