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Murine models of bone sarcomas
Jacques, Camille Renema, Nathalie Ory, Benjamin Walkley, Carl R. Grigoriadis, Agamemnon E. Heymann, Dominique
Jacques, Camille
Renema, Nathalie
Ory, Benjamin
Walkley, Carl R.
Grigoriadis, Agamemnon E.
Heymann, Dominique
Abstract
This chapter describes the procedures for inducing bone sarcoma in mice. Two models based on inoculation of cancer cells in paraosseous and intraosseous site will be described. In addition to providing technical aspects of anesthesia and surgical options, key information of cell preparation and postoperative follow-up will be discussed.
Keywords
bone sarcoma, osteosarcoma, ewing sarcoma, chondrosarcoma, cell-injection, murine preclinical models, genetically-engineered mouse models
Date
2019
Type
Book chapter
Journal
Book
Bone research protocols
Volume
Issue
Page Range
331-342
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
Collections
Relation URI
Source URL
Event URL
Open Access Status
License
All rights reserved
File Access
Controlled