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Benefits of physical activity on COPD hospitalisation depend on intensity
Donaire-Gonzalez, David Gimeno-Santos, Elena Balcells, Eva De Batlle, Jordi Ramon, Maria A. Rodriguez, Esther Farrero, Eva Benet, Marta Guerra, Stefano Sauleda, Jaume
Donaire-Gonzalez, David
Gimeno-Santos, Elena
Balcells, Eva
De Batlle, Jordi
Ramon, Maria A.
Rodriguez, Esther
Farrero, Eva
Benet, Marta
Guerra, Stefano
Sauleda, Jaume
Author
Donaire-Gonzalez, David
Gimeno-Santos, Elena
Balcells, Eva
De Batlle, Jordi
Ramon, Maria A.
Rodriguez, Esther
Farrero, Eva
Benet, Marta
Guerra, Stefano
Sauleda, Jaume
Ferrer, Antoni
Barberà, Joan A.
Rodriguez-Roisin, Robert
Gea, Joaquim
Agusti, Alvar
Antó, Josep M.
Garcia-Aymerich, Judith
PAC-COPD Study Group,
Ferrer, Jaume
PAC-COPD Study Group
Gimeno-Santos, Elena
Balcells, Eva
De Batlle, Jordi
Ramon, Maria A.
Rodriguez, Esther
Farrero, Eva
Benet, Marta
Guerra, Stefano
Sauleda, Jaume
Ferrer, Antoni
Barberà, Joan A.
Rodriguez-Roisin, Robert
Gea, Joaquim
Agusti, Alvar
Antó, Josep M.
Garcia-Aymerich, Judith
PAC-COPD Study Group,
Ferrer, Jaume
PAC-COPD Study Group
Abstract
The present study aims to disentangle the independent effects of the quantity and the intensity of physical activity on the risk reduction of chronic obstructive pulmonary disease (COPD) hospitalisations. 177 patients from the Phenotype Characterization and Course of COPD (PAC-COPD) cohort (mean±sd age 71±8 years, forced expiratory volume in 1 s 52±16% predicted) wore the SenseWear Pro 2 Armband accelerometer (BodyMedia, Pittsburgh, PA, USA) for eight consecutive days, providing data on quantity (steps per day, physically active days and daily active time) and intensity (average metabolic equivalent tasks) of physical activity. Information on COPD hospitalisations during follow-up (2.5±0.8 years) was obtained from validated centralised datasets. During follow-up 67 (38%) patients were hospitalised. There was an interaction between quantity and intensity of physical activity in their effects on COPD hospitalisation risk. After adjusting for potential confounders in the Cox regression model, the risk of COPD hospitalisation was reduced by 20% (hazard ratio (HR) 0.79, 95% CI 0.67–0.93; p=0.005) for every additional 1000 daily steps at low average intensity. A greater quantity of daily steps at high average intensity did not influence the risk of COPD hospitalisations (HR 1.01, p=0.919). Similar results were found for the other measures of quantity of physical activity. Greater quantity of low-intensity physical activity reduces the risk of COPD hospitalisation, but high-intensity physical activity does not produce any risk reduction.
Keywords
chronic obstructive pulmonary disease
Date
2015
Type
Journal article
Journal
European Respiratory Journal
Book
Volume
46
Issue
5
Page Range
1281-1289
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
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Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled