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Joint impact of physical activity and family history on the development of diabetes among urban adults in Mainland China : A pooled analysis of community-based prospective cohort studies
Xu, Fei Wang, Youfa Ware, Robert Ah Tse, Lap Wang, Zhiyong Hong, Xin Dunstan, David Owen, Neville
Xu, Fei
Wang, Youfa
Ware, Robert
Ah Tse, Lap
Wang, Zhiyong
Hong, Xin
Dunstan, David
Owen, Neville
Abstract
To examine the joint influences of physical activity (PA) and family history (FH) of diabetes on subsequent type 2 diabetes (T2D), the authors pooled and analyzed data from 2 community-based urban adult prospective cohort studies in 2011 in Nanjing, China. Among 4550 urban participants, the 3-year cumulative incidence of T2D was 5.1%. After adjustment for potential confounders, compared with those with FH+ and insufficient PA, the adjusted odds ratio (95% confidence interval) of developing T2D was 0.42 (0.18, 0.98) for participants with sufficient PA and FH+, 0.32 (0.22, 0.46) for participants with insufficient PA and FH−, and 0.15 (0.08, 0.28) for participants with sufficient PA and FH−. Such significant graduated associations between PA/FH and risk of developing T2D were also identified in either men or women, separately. Sufficient PA and FH− may jointly reduce the risk of developing T2D in urban Chinese adults.
Keywords
Date
2015
Type
Journal article
Journal
Asia-Pacific Journal of Public Health
Book
Volume
27
Issue
2
Page Range
372-381
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
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