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Health related quality of life and associated factors with medication adherence among tuberculosis patients in selected districts of Gandaki Province of Nepal
Yadav, Rajesh Kumar Kaphle, Hari Prasad Yadav, Dipendra Kumar Marahatta, Sujan Babu Shah, Naveen Prakash Baral, Sushila Khatri, Elina Ojha, Renuka
Yadav, Rajesh Kumar
Kaphle, Hari Prasad
Yadav, Dipendra Kumar
Marahatta, Sujan Babu
Shah, Naveen Prakash
Baral, Sushila
Khatri, Elina
Ojha, Renuka
Abstract
Background
Tuberculosis is one of the significant public health problems of Nepal. Adherence to medication is very important for improving quality of life and preventing complication. Adherence to tuberculosis medications has significant economic and therapeutic consequences as non-adherence patients are at greater risk of developing complications which affect their health status and overall quality of life. The study aims to determine the factors associated with medication adherence and its effect on health related quality of life among tuberculosis patients in selected districts of Gandaki Province.
Methods
A health facility based cross-sectional study was carried out among 180 tuberculosis patients registered under DOTS and receiving treatment more than or equal to 60 days. WHOQOL-BREF tools to assess quality of life and Morisky medication adherence scale (MMAS-8) was adopt to assess medication adherence. Data was entered in Epi-data and analysis was performed with the help of the Statistical Package for Social Science (SPSS). The odds ratio with a 95% CI was calculated and p-value of <0.05 was considered as cutoff for statistical significance.
Results
A total 180 TB patients were participated in this study. Overall quality of life ranges from 10.75 to 89.25 with Mean ± SD as 55.96 ± 14.65. More than three-fourth (79.4%) respondents were adhere to medication. Medication adherence and health related quality of life was found statistically significant with relationship with health workers, favourable time at DOTS centre, absence of co-infection. Participants who were highly adhered to medication had good quality of life.
Conclusion
Majority of tuberculosis patients adhering to medication had good quality of life. Especial emphasis should be given to tuberculosis patients with co-infection, health workers should behave friendly and provide appropriate counselling in order to maintain the medication adherence and quality of life.
Keywords
medication adherence, tuberculosis, Gandaki Province, Nepal
Date
2021
Type
Journal article
Journal
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Book
Volume
23
Issue
Page Range
1-9
Article Number
Article 100235
ACU Department
Collections
Relation URI
Source URL
Event URL
Open Access Status
Published as ‘gold’ (paid) open access
License
CC BY-NC-ND 4.0
File Access
Open