Left ventricular myocardial dyssynchrony is already present in nondiabetic patients with metabolic syndrome
Crendal, Edward Walther, Guillaume Dutheil, Frederic Courteix, Daniel Lesourd, Bruno Chapier, Robert Naughton, Geraldine A. Vinet, Agnes Obert, Phillippe
Crendal, Edward
Walther, Guillaume
Dutheil, Frederic
Courteix, Daniel
Lesourd, Bruno
Chapier, Robert
Naughton, Geraldine A.
Vinet, Agnes
Obert, Phillippe
Abstract
The presence of left ventricular (LV) dyssynchrony in individuals with metabolic syndrome (MetS), a predictor of type 2 diabetes (T2D), lacks clarity. We compared LV dyssynchrony in MetS individuals with and without T2D, and healthy control subjects using speckle-tracking imaging echocardiography. Ninety-two MetS participants (64 without, 28 with T2D) and 40 control subjects underwent echocardiographic and clinical/biological analyses. LV-dyssynchrony in the longitudinal axis only was present in all MetS individuals, but was not further exacerbated by T2D. Strong associations were found with systemic inflammation, abdominal obesity, and LV mass. Investigations of myocardial dyssynchrony in the nondiabetic MetS stage might facilitate timely and more effective prevention.
Keywords
Date
2014
Type
Journal article
Journal
Canadian Journal of Cardiology
Book
Volume
30
Issue
3
Page Range
320-324
Article Number
ACU Department
School of Behavioural and Health Sciences
Faculty of Health Sciences
Faculty of Health Sciences