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Thirty years of evidence on the efficacy of drug treatments for chronic heart failure with reduced ejection fraction: A network meta-analysis
Burnett, Heather Earley, Amy Voors, Adriaan A. Senni, Michele McMurray, John Deschaseaux, Celine Cope, Shannon
Burnett, Heather
Earley, Amy
Voors, Adriaan A.
Senni, Michele
McMurray, John
Deschaseaux, Celine
Cope, Shannon
Abstract
Treatments that reduce mortality and morbidity in patients with heart failure with reduced ejection fraction, including angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB), β-blockers (BB), mineralocorticoid receptor antagonists (MRA), and angiotensin receptor–neprilysin inhibitors (ARNI), have not been studied in a head-to-head fashion. This network meta-analysis aimed to compare the efficacy of these drugs and their combinations regarding all-cause mortality in patients with heart failure with reduced ejection fraction.
Keywords
drug combinations, drug therapy, heart failure, mortality, network meta-analysis
Date
2017
Type
Journal article
Journal
Circulation: Heart Failure
Book
Volume
10
Issue
1
Page Range
1-13
Article Number
ACU Department
Collections
Relation URI
Source URL
Event URL
Open Access Status
Open access
License
File Access
Open
Notes
© 2017 The Authors. Circulation: Heart Failure is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDervis License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.