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Synchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cells
Sheridan, Erin J. Austin, Christopher J. D. Aitken, Jade B. Vogt, Stefan Jolliffe, Katrina A. Harris, Hugh H. Rendina, Louis M.
Sheridan, Erin J.
Austin, Christopher J. D.
Aitken, Jade B.
Vogt, Stefan
Jolliffe, Katrina A.
Harris, Hugh H.
Rendina, Louis M.
Abstract
The first example of synchrotron X-ray fluorescence imaging of cultured mammalian cells in cyclic peptide research is reported. The study reports the first quantitative analysis of the incorporation of a bromine-labelled cyclic RGD peptide and its effects on the biodistribution of endogenous elements (for example, K and Cl) within individual tumor cells.
Keywords
XRF, microprobe, RGD peptide, tumor cells
Date
2013
Type
Journal article
Journal
Journal of Synchrotron Radiation
Book
Volume
20
Issue
2
Page Range
226-233
Article Number
ACU Department
Collections
Relation URI
Source URL
Event URL
Open Access Status
Open access
License
CC BY 4.0
File Access
Open