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Home-based pulmonary rehabilitation early after hospitalisation in COPD (early HomeBase) : Protocol for a randomised controlled trial
Cox, Narelle Lahham, Aroub McDonald, Christine F. Mahal, Ajay O'Halloran, Paul Hepworth, Graham Spencer, Lissa McNamara, Renae J. Bondarenko, Janet Macdonald, Heather
Cox, Narelle
Lahham, Aroub
McDonald, Christine F.
Mahal, Ajay
O'Halloran, Paul
Hepworth, Graham
Spencer, Lissa
McNamara, Renae J.
Bondarenko, Janet
Macdonald, Heather
Abstract
Introduction: Chronic obstructive pulmonary disease (COPD) is characterised by exacerbations of respiratory disease, frequently requiring hospital admission. Pulmonary rehabilitation can reduce the likelihood of future hospitalisation, but programme uptake is poor. This study aims to compare hospital readmission rates, clinical outcomes and costs between people with COPD who undertake a home-based programme of pulmonary rehabilitation commenced early (within 2 weeks) of hospital discharge with usual care.
Methods: A multisite randomised controlled trial, powered for superiority, will be conducted in Australia. Eligible patients admitted to one of the participating sites for an exacerbation of COPD will be invited to participate. Participants will be randomised 1:1. Intervention group participants will undertake an 8-week programme of home-based pulmonary rehabilitation commencing within 2 weeks of hospital discharge. Control group participants will receive usual care and a weekly phone call for attention control. Outcomes will be measured by a blinded assessor at baseline, after the intervention (week 9–10 posthospital discharge), and at 12 months follow-up. The primary outcome is hospital readmission at 12 months follow-up.
Ethics and dissemination: Human Research Ethics approval for all sites provided by Alfred Health (Project 51216). Findings will be published in peer-reviewed journals, conferences and lay publications.
Trial registration number: ACTRN12619001122145.
Keywords
Chronic obstructive pulmonary disease, COPD, respiratory disease, pulmonary rehabilitation, hospitalisation, Australia
Date
2021
Type
Journal article
Journal
Book
Volume
8
Issue
1
Page Range
1-9
Article Number
ACU Department
School of Allied Health
Faculty of Health Sciences
Faculty of Health Sciences
Collections
Relation URI
Event URL
Open Access Status
Published as ‘gold’ (paid) open access
License
File Access
Open
Open
Open
Notes
© Author(s) (or their employer(s)) 2021
This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non- commercial. See: http:// creativecommons. org/ licenses/ by- nc/ 4. 0/.
This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non- commercial. See: http:// creativecommons. org/ licenses/ by- nc/ 4. 0/.