Loading...
Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men
Holwerda, Andrew M. Paulussen, Kevin J. M. Overkamp, Maarten Goessens, Joy P. B. Kramer, Irene-Fleur Wodzig, Will K. W. H. Verdijk, Lex B. de Groot, Lisette C. P. G. M. Van Loon, Luc
Holwerda, Andrew M.
Paulussen, Kevin J. M.
Overkamp, Maarten
Goessens, Joy P. B.
Kramer, Irene-Fleur
Wodzig, Will K. W. H.
Verdijk, Lex B.
de Groot, Lisette C. P. G. M.
Van Loon, Luc
Abstract
[Extract] The age-related decline in skeletal muscle mass and strength, termed sarcopenia, is accompanied by impairments in functional capacity and an increased risk of developing chronic metabolic diseases (4). Whereas basal muscle protein synthesis and breakdown rates appear to be unaffected by age (27), the muscle protein synthetic response to the main anabolic stimuli, namely food intake and physical activity, seem to be blunted in older individuals (41). This anabolic resistance is now considered as a central factor contributing to the progression of sarcopenia.
Keywords
Date
2019
Type
Book chapter
Journal
Book
Dietary protein to support active aging
Volume
Issue
Page Range
53-73
Article Number
ACU Department
Centre for Exercise and Nutrition
Faculty of Health Sciences
Faculty of Health Sciences
Collections
Relation URI
Source URL
Event URL
Open Access Status
Open access
License
File Access
Open