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Maternal lifestyle interventions : Targeting preconception health
Moholdt, Trine Hawley, John A.
Moholdt, Trine
Hawley, John A.
Author
Abstract
About one-third of women of reproductive age are obese, predisposing both mother and baby to unfavourable pregnancy outcomes and initiating an intergenerational cycle of chronic metabolic disorders. Here we summarise recent research on the influence of maternal metabolic health on offspring susceptibility to future cardiometabolic diseases. Current primary lifestyle approaches (i.e., diet and exercise interventions) to halt the succession of inherited and epigenetic metabolic abnormalities have met with limited success due to late implementation, poor adherence, and/or generic guidelines. In our opinion, such interventions must commence prior to conception to improve both maternal and child health outcomes, with new approaches urgently needed to increase adherence to primary lifestyle changes among reproductive-age women.
Keywords
pregnancy, epigenetic modifications, gestational diabetes mellitus, high-intensity exercise, diet, obesity, time-restricted eating
Date
2020
Type
Journal article
Journal
Trends in Endocrinology and Metabolism
Book
Volume
31
Issue
8
Page Range
561-569
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
Collections
Relation URI
Source URL
Event URL
Open Access Status
Published as ‘gold’ (paid) open access
License
CC BY-NC-ND 4.0
File Access
Open