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Acute endurance exercise induces nuclear p53 abundance in human skeletal muscle
Tachtsis, Bill ; Smiles, William ; Lane, Steven C. ; Hawley, John Alan ; Camera, Donny Michael
Tachtsis, Bill
Smiles, William
Lane, Steven C.
Hawley, John Alan
Camera, Donny Michael
Abstract
The tumor suppressor protein p53 may have regulatory roles in exercise response-adaptation processes such as mitochondrial biogenesis and autophagy, although its cellular location largely governs its biological role. We investigated the subcellular localization of p53 and selected signaling targets in human skeletal muscle following a single bout of endurance exercise.
Keywords
mitochondrial biogenesis, autophagy, mitochondrial turnover, cell signaling, skeletal muscle
Date
2016
Type
Journal article
Journal
Frontiers in Physiology
Book
Volume
7
Issue
144
Page Range
1-10
Article Number
ACU Department
School of Behavioural and Health Sciences
Faculty of Health Sciences
Mary MacKillop Institute for Health Research
Non-faculty
Faculty of Health Sciences
Mary MacKillop Institute for Health Research
Non-faculty
Relation URI
Source URL
Event URL
Open Access Status
Open access
License
CC BY 4.0
File Access
Open
