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Quality of life in sarcopenia and frailty
Rizzoli, Rene Reginster, Jean-Yves Arnal, Jean-Francois Bautmans, Ivan Beaudart, Charlotte Bischoff-Ferrari, Heike Biver, Emmanuel Boonen, Steven Brandi, Maria-Luisa Chines, Arkadi
Rizzoli, Rene
Reginster, Jean-Yves
Arnal, Jean-Francois
Bautmans, Ivan
Beaudart, Charlotte
Bischoff-Ferrari, Heike
Biver, Emmanuel
Boonen, Steven
Brandi, Maria-Luisa
Chines, Arkadi
Author
Rizzoli, Rene
Reginster, Jean-Yves
Arnal, Jean-Francois
Bautmans, Ivan
Beaudart, Charlotte
Bischoff-Ferrari, Heike
Biver, Emmanuel
Boonen, Steven
Brandi, Maria-Luisa
Chines, Arkadi
Cooper, Cyrus
Epstein, Sol
Fielding, Roger A.
Goodpaster, Bret
Kanis, John A.
Kaufman, J.
Laslop, A.
Malafarina, Vincenzo
Mañas, Leocadio Rodriguez
Mitlak, B.
Oreffo, Richard O.
Petermans, J.
Reid, Kieran
Rolland, Y.
Sayer, A. A.
Tsouderos, Y.
Visser, Marjolein
Bruyère, O.
Reginster, Jean-Yves
Arnal, Jean-Francois
Bautmans, Ivan
Beaudart, Charlotte
Bischoff-Ferrari, Heike
Biver, Emmanuel
Boonen, Steven
Brandi, Maria-Luisa
Chines, Arkadi
Cooper, Cyrus
Epstein, Sol
Fielding, Roger A.
Goodpaster, Bret
Kanis, John A.
Kaufman, J.
Laslop, A.
Malafarina, Vincenzo
Mañas, Leocadio Rodriguez
Mitlak, B.
Oreffo, Richard O.
Petermans, J.
Reid, Kieran
Rolland, Y.
Sayer, A. A.
Tsouderos, Y.
Visser, Marjolein
Bruyère, O.
Abstract
The reduced muscle mass and impaired muscle performance that define sarcopenia in older individuals are associated with increased risk of physical limitation and a variety of chronic diseases. They may also contribute to clinical frailty. A gradual erosion of quality of life (QoL) has been evidenced in these individuals, although much of this research has been done using generic QoL instruments, particularly the SF-36, which may not be ideal in older populations with significant comorbidities. This review and report of an expert meeting presents the current definitions of these geriatric syndromes (sarcopenia and frailty). It then briefly summarizes QoL concepts and specificities in older populations and examines the relevant domains of QoL and what is known concerning QoL decline with these conditions. It calls for a clearer definition of the construct of disability, argues that a disease-specific QoL instrument for sarcopenia/frailty would be an asset for future research, and discusses whether there are available and validated components that could be used to this end and whether the psychometric properties of these instruments are sufficiently tested. It calls also for an approach using utility weighting to provide some cost estimates and suggests that a time trade-off study could be appropriate.
Keywords
Age, Aging, Muscle weakness, Quality of life, Malnutrition
Date
2013
Type
Journal article
Journal
Calcified Tissue International
Book
Volume
93
Issue
2
Page Range
101-120
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
Collections
Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled