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Short time horizons for fracture prediction tools : Time for a rethink
McCloskey, E. V. Borgstrom, F. Cooper, C. Harvey, N. C. Javaid, M. K. Lorentzon, M. Kanis, J. A.
McCloskey, E. V.
Borgstrom, F.
Cooper, C.
Harvey, N. C.
Javaid, M. K.
Lorentzon, M.
Kanis, J. A.
Abstract
[Extract] Prior fragility fracture is a well-established risk factor for a future fracture [1,2,3,4]. The population relative risk of having a subsequent hip fracture or other osteoporotic fracture is approximately 2-fold higher for most types of prior fracture. However, many studies suggest that the increase in risk is not constant with time or age. Indeed, the risk of a subsequent osteoporotic fracture is particularly acute immediately after an index fracture and wanes progressively over the next 2 years [4,5,6,7,8,9] but thereafter remains higher than that of the general population (Fig. 1). The early phase of particularly high risk has been termed imminent risk [9]. This transiency, which is not currently accommodated in any of the available fracture risk assessment tools, suggests that treatment given to patients immediately after a fracture might avoid a higher number of new fractures compared with treatment given at a later date.
Keywords
Date
2021
Type
Journal article
Journal
Osteoporosis International
Book
Volume
32
Issue
6
Page Range
1019-1025
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
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Relation URI
Source URL
Event URL
Open Access Status
Published as green open access
License
File Access
Controlled
Open
Open