Loading...
Hypertension among people living with human immunodeficiency virus in sub-Saharan Africa : a systematic review and meta-analysis
Chen, Alexander Chan, Yih Kai Mocumbi, Ana Ojji, Dike Waite, Laura Beilby, Justin Codde, Jim Dobe, Igor Nkeh-Chungag, Benedicta Ngwenchi Damasceno, Albertino
Chen, Alexander
Chan, Yih Kai
Mocumbi, Ana
Ojji, Dike
Waite, Laura
Beilby, Justin
Codde, Jim
Dobe, Igor
Nkeh-Chungag, Benedicta Ngwenchi
Damasceno, Albertino
Author
Chen, Alexander
Chan, Yih Kai
Mocumbi, Ana
Ojji, Dike
Waite, Laura
Beilby, Justin
Codde, Jim
Dobe, Igor
Nkeh-Chungag, Benedicta Ngwenchi
Damasceno, Albertino
Stewart, Simon
Chan, Yih Kai
Mocumbi, Ana
Ojji, Dike
Waite, Laura
Beilby, Justin
Codde, Jim
Dobe, Igor
Nkeh-Chungag, Benedicta Ngwenchi
Damasceno, Albertino
Stewart, Simon
Abstract
We performed a systematic review and meta-analysis of hypertension in people living with human immunodeficiency virus (HIV) in sub-Saharan Africa (SSA). We searched the PubMed, Google Scholar, African Index Medicus, and Embase databases to identify studies published from January 1, 2010, to December 31, 2021. We used a random-effects model to estimate the pooled prevalence of hypertension and mean SBP/DBP level on a sex-specific basis. We included 48 studies reporting data on a pooled sample of 193,843 people living with HIV (PLW-HIV) in SSA. The pooled mean SBP/DBP level was 120 (95% CI 113–128)/77 (95%CI 72–82) mmHg, while the overall pooled prevalence of hypertension was 21.9% (95% CI 19.9–23.9%). Further meta-regression analyses suggested that the prevalence of hypertension was 1.33 times greater in males, 1.23 times greater in individuals receiving antiretroviral therapy (ART) and 1.45 times greater in those individuals with a CD4-count ≥ 200. This meta-analysis of the contemporary pattern of BP levels among PLW-HIV in SSA, suggests that around one in five of such individuals also have hypertension. Given the further context of greater access to ART and subsequently greater longevity, study findings support calls to integrate cardiovascular management into routine HIV care.
Keywords
hypertension, human immunodeficiency virus (HIV), Sub-Saharan Africa, systematic review, cardiovascular management, HIV infections
Date
2024
Type
Journal article
Journal
Book
Volume
14
Issue
Page Range
1-11
Article Number
ACU Department
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Faculty of Health Sciences
Collections
Relation URI
Event URL
Open Access Status
Published as ‘gold’ (paid) open access
License
File Access
Open
Open
Open
Notes
© The Author(s) 2024
This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creativecommons. org/ licenses/ by- nc- nd/4. 0/.
This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creativecommons. org/ licenses/ by- nc- nd/4. 0/.