Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study : Analysis of 36-month observational data
Tabrizi, Sarah Scahill, Rachael Owen, Gail Durr, Alexandra Leavitt, Blair Roos, Raymund Borowsky, Beth Landwehrmeyer, Bernhard Frost, Chris Johnson, Hans
Tabrizi, Sarah
Scahill, Rachael
Owen, Gail
Durr, Alexandra
Leavitt, Blair
Roos, Raymund
Borowsky, Beth
Landwehrmeyer, Bernhard
Frost, Chris
Johnson, Hans
Abstract
Background: TRACK-HD is a multinational prospective observational study of Huntington's disease (HD) that examines clinical and biological findings of disease progression in individuals with premanifest HD (preHD) and early-stage HD. We aimed to describe phenotypic changes in these participants over 36 months and identify baseline predictors of progression.
Keywords
Date
2013
Type
Journal article
Journal
Lancet Neurology
Book
Volume
12
Issue
7
Page Range
637-649
Article Number
ACU Department
Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled