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Is Developmental Coordination Disorder a Dysconnection Syndrome?
Jessica Tallet Peter Wilson
Jessica Tallet
Peter Wilson
Author
Abstract
Purpose of Review
Classical view of disconnection refers to damage in white matter connections leading to behavioral deficits on sensorimotor and cognitive tasks in brain-injured patients. A more recent conception refers to dysconnection, that means abnormal connectivity between brain regions, as found in psychiatric, neurodegenerative, and neurodevelopmental disorders. The present paper aims to explore the hypothesis that Developmental Coordination Disorder (DCD) presents a set of neural, behavioral, and cognitive signs that suggest a dysconnection syndrome.
Recent Findings
Current literature on DCD using behavioral and neuroimaging measures suggests several dysconnections (1) between hemispheres, (2) within hemispheres, (3) within the cortico-subcortical loops, and (4) in the cortico-spinal tract.
Summary
Brain dysconnections could explain the diversity of behavioral and cognitive deficits in DCD such as deficits in motor control during inter-limb rhythmic coordination and unimanual movements, deficits in motor imagery, planning and execution, and learning difficulties. Future studies using behavioral and neuroimaging measures should endeavor to map the relationship between putative dysconnections and behavioral and cognitive deficits in DCD. It will also be necessary to identify DCD-specific dysconnections compared with other neurodevelopmental disorders.
Keywords
structural connectivity, functional connectivity, white matter, disconnection, electroencephalography, magnetic resonance imaging, transcranial magnetic stimulation
Date
2020
Type
Journal article
Journal
Current Developmental Disorders Reports (online)
Book
Volume
7
Issue
Page Range
1-13
Article Number
ACU Department
School of Behavioural and Health Sciences
Faculty of Health Sciences
Faculty of Health Sciences
Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled