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Intra-articular injection of photo-activated platelet-rich plasma in patients with knee osteoarthritis: a double-blind, randomized controlled pilot study

Paterson, Kade L.
Nicholls, Melissa
Bennell, Kim L.
Bates, Dan
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Abstract
Improvements in knee osteoarthritis (OA) symptoms with platelet-rich plasma (PRP) have been attributed to its ability to modify intra-articular inflammatory processes. Photo-activation of peripheral blood also improves inflammatory mediators associated with OA, however combined photo-activated PRP (PA-PRP) has not been investigated. This pilot study assessed the feasibility, safety and symptomatic and functional change following injections of PA-PRP compared to hyaluronic acid (HA) in people with knee osteoarthritis (OA).
Keywords
Cartilage, Pain, Arthritis, Musculoskeletal diseases
Date
2016
Type
Journal article
Journal
BMC Musculoskeletal Disorders
Book
Volume
17
Issue
1
Page Range
1-9
Article Number
ACU Department