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Race, regionality and pre-diabetes in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study

Lee, Loretta T.
Alexandrov, Anne W.
Howard, Virginia J.
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Abstract
Objective: To determine the association between race, region and pre-diabetes. Method: The study used 2003–2007 United States baseline data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study for this cross-sectional analysis. Participants in this study were 45 years or older at recruitment. Logistic regression was used to assess whether race and region are associated with pre-diabetes independent of demographics, socioeconomic factors and risk factors. Results: Twenty-four percent of the study participants (n = 19,889) had pre-diabetes. The odds ratio (95% confidence interval) for having pre-diabetes was 1.28 (1.19–1.36) for blacks relative to whites and 1.18 (1.10–1.26) for people living in the Stroke Belt region relative to the other parts of the United States. The odds of having pre-diabetes for Stroke Belt participants changed minimally after additional adjustment for race (OR = 1.20; 1.13–1.28), age and sex (OR = 1.24; 1.16–1.32), socioeconomic status (OR = 1.22; 1.15–1.31) and risk factors (OR = 1.26; 1.17–1.35). In the adjusted model, being black was independently associated with pre-diabetes (OR = 1.19; 1.10–1.28). Conclusion: The prevalence of pre-diabetes was higher for both blacks and whites living in the Stroke Belt relative to living outside the Stroke Belt, and the prevalence of pre-diabetes was higher for blacks independent of region.
Keywords
pre-diabetes, stroke belt region, non-stroke belt region, REGARDS study, type 2 diabetes, diabetes, odds ratios, fasting blood glucose, impaired glucose tolerance, impaired fasting glucose
Date
2014
Type
Journal article
Journal
Preventive Medicine
Book
Volume
63
Issue
June
Page Range
43-47
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ACU Department
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Open Access Status
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Controlled
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