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Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults
Scott, David Sanders, Kerrie M. Aitken, Dawn Hayes, Alan Ebeling, Peter R. Jones, Graeme
Scott, David
Sanders, Kerrie M.
Aitken, Dawn
Hayes, Alan
Ebeling, Peter R.
Jones, Graeme
Abstract
Objectives To determine whether obesity concurrent with sarcopenia (low muscle mass) or dynapenia (low muscle strength) is associated with increased falls risk in middle-aged and older adults. Methods 5-year prospective cohort study including 674 community-dwelling volunteers (mean ± SD age 61.4 ± 7.0 years; 48% female). Sarcopenia and dynapenia were defined as lowest sex-specific tertiles for dual-energy X-ray (DXA)-assessed appendicular lean mass (adjusted for height and fat mass) or lower-limb strength, respectively. Obesity was defined as the highest tertiles of DXA-assessed total or trunk fat mass. Change in falls risk was calculated using the Physiological Profile Assessment (z-scores: 0-1 = mild increased risk; 1-2 = moderate increased risk; > 2 = marked increased risk). Results Multivariable linear regression analyses revealed mild but significantly increased falls risk scores for dynapenic obesity (change in mean z-score compared to non-dynapenic, non-obese group: 0.33, 95% CI 0.06-0.59 [men] and 0.46, 95% CI 0.21-0.72 [women]) and dynapenia (0.25, 95% CI 0.05-0.46 [women only]). Conclusions Dynapenic obesity, but not sarcopenic obesity, is predictive of increased falls risk score in middle-aged and older adults.s In clinical settings, muscle function assessments may be useful for predicting falls risk in obese patients.
Keywords
Date
2014
Type
Journal article
Journal
Obesity
Book
Volume
22
Issue
6
Page Range
1568-1574
Article Number
ACU Department
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Source URL
Event URL
Open Access Status
License
File Access
Controlled