Mattias Lorentzon


Contact categoryResearcher (past)
Job titleProfessor
Research instituteMary MacKillop Institute for Health Research
Faculty of Health Sciences

Research outputs

Sarcopenia definitions and their association with fracture risk in older Swedish women
Gandham, Anoohya, Gregori, Giulia, Johansson, Lisa, Johansson, Helena, Harvey, Nicholas, Vandenput, Liesbeth, McCloskey, Eugene, Kanis, John Anthony, Litsne, Henrik, Axelsson, Kristian and Lorentzon, Karl Mattias. (2024). Sarcopenia definitions and their association with fracture risk in older Swedish women. JBMR Plus. 39(4), pp. 453-461. https://doi.org/10.1093/jbmr/zjae026

Journal article

Hemoglobin Levels Improve Fracture Risk Prediction in Addition to FRAX Clinical Risk Factors and Bone Mineral Density
Jaiswal, Raju, Johansson, Helena, Axelsson, Kristian, Magnusson, Per, Harvey, Nicholas, Vandenput, Liesbeth, McCloskey, Eugene, Kanis, John Anthony, Litsne, Henrik, Johansson, Lisa and Lorentzon, Karl Mattias. (2023). Hemoglobin Levels Improve Fracture Risk Prediction in Addition to FRAX Clinical Risk Factors and Bone Mineral Density. The Journal of Clinical Endocrinology and Metabolism. 108(12), pp. 1479-1488. https://doi.org/10.1210/clinem/dgad399

Journal article

A new FRAX model for Brazil
Albergaria, Ben Hur, Zerbini, C. A F, Lazaretti-Castro, M. Lazaretti-Castro, Eis, Lazaretti-Castro, Vilaca, Tatiane, Johansson, Helena, Harvey, Nicholas, Liu, Enwu, Vandenput, Liesbeth, Lorentzon, Karl Mattias, Schini, Marian, McCloskey, Eugene and Kanis, John Anthony. (2023). A new FRAX model for Brazil. Archives of Osteoporosis. 18(1), pp. 1-8. https://doi.org/10.1007/s11657-023-01354-3

Journal article

An overview of the use of the fracture risk assessment tool (FRAX) in osteoporosis
Schini, M., Johansson, Helena, Harvey, Nicholas, Lorentzon, Karl Mattias, Kanis, John Anthony and McCloskey, Eugene. (2024). An overview of the use of the fracture risk assessment tool (FRAX) in osteoporosis. Journal of Endocrinological Investigation. 47(3), pp. 501-511. https://doi.org/10.1007/s40618-023-02219-9

Journal article

Low Circulating Valine Associate With High Risk of Hip Fractures
Grahnemo, Louise, Eriksson, Anna L., Nethander, Maria, Johansson, Robert, Lorentzon, Karl Mattias, Mellstrom, Dan, Pettersson-Kymmer, Ulrika and Ohlsson, Claes. (2023). Low Circulating Valine Associate With High Risk of Hip Fractures. The Journal of Clinical Endocrinology and Metabolism. 108(11), pp. 1384-1393. https://doi.org/10.1210/clinem/dgad268

Journal article

Adjusting conventional FRAX estimates of fracture probability according to the number of prior falls in the preceding year
Kanis, John A., Johansson, Helena, Harvey, Nicholas C., Lorentzon, Mattias, Liu, Enwu, Vandenput, Liesbeth, Morin, Suzanne, Leslie, William D. and McCloskey, Eugene V.. (2023). Adjusting conventional FRAX estimates of fracture probability according to the number of prior falls in the preceding year. Osteoporosis International. 34(3), pp. 479-487. https://doi.org/10.1007/s00198-022-06633-2

Journal article

An assessment of intervention thresholds for high fracture risk in Chile
Lopez Gavilanez, Enrique, Luis, Imaicela N., Mario, Navarro G., Johansson, Helena, Harvey, Nicholas C., Lorentzon, Mattias, Liu, Enwu, Vandenput, Liesbeth, McCloskey, Eugene V. and Kanis, John A.. (2023). An assessment of intervention thresholds for high fracture risk in Chile. Archives of Osteoporosis. 18(1), p. Article 11. https://doi.org/10.1007/s11657-022-01198-3

Journal article

Primary hyperparathyroidism and fracture probability
Kanis, John A., Harvey, Nicholas C., Liu, Enwu, Vandenput, Liesbeth, Lorentzon, Mattias, McCloskey, Eugene V., Bouillon, Roger, Abrahamsen, Bo, Rejnmark, Lars, Johansson, Helena and The Danish Primary Hyperparathyroidism Study Group. (2023). Primary hyperparathyroidism and fracture probability. Osteoporosis International. 34(3), pp. 489-499. https://doi.org/10.1007/s00198-022-06629-y

Journal article

Greater pQCT calf muscle density is associated with lower fracture risk, independent of FRAX, falls and BMD : A meta-analysis in the Osteoporotic Fractures in Men (MrOS) Study
Harvey, Nicholas C., Orwoll, Eric, Cauley, Jane A., Kwok, Timothy, Karlsson, Magnus K., Rosengren, Björn, Ribom, Eva, Cawthon, Peggy M., Ensrud, Kristine, Liu, Enwu, Laskou, Faidra, Ward, Kate A., Dennison, Elaine M., Cooper, Cyrus, Kanis, John A., Vandenput, Liesbeth, Lorentzon, Mattias, Ohlsson, Claes, Mellström, Dan, ... McCloskey, Eugene. (2022). Greater pQCT calf muscle density is associated with lower fracture risk, independent of FRAX, falls and BMD : A meta-analysis in the Osteoporotic Fractures in Men (MrOS) Study. JBMR Plus. 6(12), p. e10696. https://doi.org/10.1002/jbm4.10696

Journal article

Osteoporosis treatment in Austria—assessment of FRAX‑based intervention thresholds for high and very high fracture risk
Dimai, Hans P., Johansson, Helena, Harvey, Nicholas C., Lorentzon, Mattias, Liu, Enwu, Vandenput, Liesbeth, Fahrleitner-Pammer, Astrid, Pietschmann, Peter, Muschitz, Christian, McCloskey, Eugene V. and Kanis, John A.. (2022). Osteoporosis treatment in Austria—assessment of FRAX‑based intervention thresholds for high and very high fracture risk. Archives of Osteoporosis. 17, p. Article 141. https://doi.org/10.1007/s11657-022-01175-w

Journal article

One-year supplementation with Lactobacillus reuteri ATCC PTA 6475 counteracts a degradation of gut microbiota in older women with low bone mineral density
Li, Peishun, Ji, Boyang, Luo, Hao, Sundh, Daniel, Lorentzon, Mattias and Nielsen, Jens. (2022). One-year supplementation with Lactobacillus reuteri ATCC PTA 6475 counteracts a degradation of gut microbiota in older women with low bone mineral density. npj Biofilms and Microbiomes. 8(84), pp. 1-10. https://doi.org/10.1038/s41522-022-00348-2

Journal article

Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures
Kanis, John Anthony, Johansson, Helena, Harvey, Nicholas, Gudnason, Vilmundur, Sigurdsson, Gunnar, Siggeirsdottir, Kristin, Lorentzon, Karl Mattias, Liu, Enwu, Vandenput, Liesbeth and McCloskey, Eugene. (2022). Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures. Osteoporosis International. 33, pp. 2507-2515. https://doi.org/10.1007/s00198-022-06550-4

Journal article

Osteoporosis epidemiology using international cohorts
Lorentzon, Mattias and Abrahamsen, Bo. (2022). Osteoporosis epidemiology using international cohorts. Current Opinion in Rheumatology. 34(5), pp. 280-288. https://doi.org/10.1097/BOR.0000000000000885

Journal article

Young adult male patients with childhood-onset IBD have increased risks of compromised cortical and trabecular bone microstructures
Sigurdsson, Gudmundur Vignir, Schmidt, Susanne, Mellström, Dan, Ohlsson, Claes, Saalman, Robert and Lorentzon, Mattias. (2022). Young adult male patients with childhood-onset IBD have increased risks of compromised cortical and trabecular bone microstructures. Inflammatory Bowel Diseases. 29(7), p. 1065–1072. https://doi.org/10.1093/ibd/izac181

Journal article

The association between peripheral arterial disease and risk for hip fractures in elderly men is not explained by low hip bone mineral density. Results from the MrOS Sweden study
Bokrantz, Tove, Manhem, Karin, Lorentzon, Mattias, Karlsson, Magnus, Ljunggren, Östen, Ohlsson, Claes and Mellström, Dan. (2022). The association between peripheral arterial disease and risk for hip fractures in elderly men is not explained by low hip bone mineral density. Results from the MrOS Sweden study. Osteoporosis International. 33, pp. 2607-2617. https://doi.org/10.1007/s00198-022-06535-3

Journal article

Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability — Results from the Women’s Health Initiative hormone therapy trials
Lorentzon, Mattias, Johansson, Helena, Harvey, Nicholas C., Liu, Enwu, Vandenput, Liesbeth, Crandall, Carolyn J., Cauley, Jane A., LeBoff, Meryl S., McCloskey, Eugene V. and Kanis, John A.. (2022). Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability — Results from the Women’s Health Initiative hormone therapy trials. Osteoporosis International. 33(11), pp. 2297-2305. https://doi.org/10.1007/s00198-022-06483-y

Journal article

Population screening for fracture risk in postmenopausal women — a logical step in reducing the osteoporotic fracture burden? [Editorial]
McCloskey, E., Chotiyarnwong, P., Harvey, N., Lorentzon, M. and Kanis, J. A.. (2022). Population screening for fracture risk in postmenopausal women — a logical step in reducing the osteoporotic fracture burden? [Editorial]. Osteoporosis International. 33, pp. 1631-1637. https://doi.org/10.1007/s00198-022-06419-6

Journal article

Is it time to consider population screening for fracture risk in postmenopausal women? A position paper from the International Osteoporosis Foundation Epidemiology/Quality of Life Working Group
Chotiyarnwong, P., McCloskey, E. V., Harvey, N. C., Lorentzon, Mattias, Prieto-Alhambra, D, Abrahamsen, B., Adachi, J., Borgström, F., Bruyere, O., Carey, J., Clark, P., Cooper, C., Curtis, E., Dennison, E., Diaz-Curiel, M., Dimai, H., Grigorie, D., Hiligsmann, M., Khashayar, P., ... Kanis, J. A.. (2022). Is it time to consider population screening for fracture risk in postmenopausal women? A position paper from the International Osteoporosis Foundation Epidemiology/Quality of Life Working Group. Archives of Osteoporosis. 17(1), p. Article 87. https://doi.org/10.1007/s11657-022-01117-6

Journal article

Anemia is associated with increased risk of non-vertebral osteoporotic fractures in elderly men : the MrOS Sweden cohort
Kristjansdottir, Hallgerdur, Mellstrom, Dan, Johansson, Peter, Karlsson, Magnus, Vandenput, Liesbeth, Lorentzon, Karl Mattias, Herlitz, Hans, Ohlsson, Claes, Lerner, Ulf and Lewerin, Catharina. (2022). Anemia is associated with increased risk of non-vertebral osteoporotic fractures in elderly men : the MrOS Sweden cohort. Archives of Osteoporosis. 17(1), pp. 1-9. https://doi.org/10.1007/s11657-022-01130-9

Journal article

Analysis of Comorbidities, Clinical Outcomes, and Parathyroidectomy in Adults With Primary Hyperparathyroidism
Axelsson, Kristian F., Wallander, Märit, Johansson, Helena, Harvey, Nicholas C., Vandenput, Liesbeth, McCloskey, Eugene, Liu, Enwu, Kanis, John A., Litsne, Henrik and Lorentzon, Mattias. (2022). Analysis of Comorbidities, Clinical Outcomes, and Parathyroidectomy in Adults With Primary Hyperparathyroidism. JAMA Network Open. 5(6), p. Article e2215396. https://doi.org/10.1001/jamanetworkopen.2022.15396

Journal article

Update of the fracture risk prediction tool FRAX : a systematic review of potential cohorts and analysis plan
Vandenput, Liesbeth, Johansson, Helena, McCloskey, E, Liu, Enwu, Åkesson, K, Anderson, F, Azagra, R, Bager, C, Beaudart, C, Bischoff-Ferrari, H, Biver, E, Bruyère, O, Cauley, J, Lorentzon, Karl Mattias and Kanis, John Anthony. (2022). Update of the fracture risk prediction tool FRAX : a systematic review of potential cohorts and analysis plan. Osteoporosis International. 33(10), pp. 2103-2136. https://doi.org/10.1007/s00198-022-06435-6

Journal article

Trabecular bone score adjustment for the Fracture Risk Assessment tool (FRAX®) [Letter]
McCloskey, Eugene, Harvey, Nicholas C., Lorentzon, Mattias, Johansson, Helena and Kanis, John A.. (2022). Trabecular bone score adjustment for the Fracture Risk Assessment tool (FRAX®) [Letter]. Calcified Tissue International. 111(2), pp. 226-227. https://doi.org/10.1007/s00223-022-00994-w

Journal article

Improved fracture risk prediction by adding VFA-identified vertebral fracture data to BMD by DXA and clinical risk factors used in FRAX
Johansson, L, Johansson, H., Axelsson, K. F., Litsne, H., Harvey, N. C., Liu, E., Leslie, W. D., Vandenput, L., McCloskey, E., Kanis, J. A. and Lorentzon, M.. (2022). Improved fracture risk prediction by adding VFA-identified vertebral fracture data to BMD by DXA and clinical risk factors used in FRAX. Osteoporosis International. 33(8), pp. 1725-1738. https://doi.org/10.1007/s00198-022-06387-x

Journal article

The outcome of an automated assessment of trabecular pattern in intraoral radiographs as a fracture risk predictor
Gullberg, Joanna, Sundh, Daniel, Johansson, Lisa, Isberg, Per-Erik, Lorentzon, Mattias and Lindh, Christina. (2022). The outcome of an automated assessment of trabecular pattern in intraoral radiographs as a fracture risk predictor. Dentomaxillofacial Radiology. 51(5), p. Article 20210483. https://doi.org/10.1259/dmfr.20210483

Journal article

Potential adverse effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on bisphosphonate efficacy : An exploratory post hoc analysis from a randomized controlled trial of clodronate
Zheng, Zhangan, Johansson, Helena, Harvey, Nicholas C., Lorentzon, Mattias, Vandenput, Liesbeth, Liu, Enwu, Kanis, John A. and McCloskey, Eugene V.. (2022). Potential adverse effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on bisphosphonate efficacy : An exploratory post hoc analysis from a randomized controlled trial of clodronate. Journal of Bone and Mineral Research. 37(6), pp. 1117-1124. https://doi.org/10.1002/jbmr.4548

Journal article

Incidence of hip fracture in Saudi Arabia and the development of a FRAX model
Saleh, Yousef A. L., Sulimani, Riad A., Alomary, Shaker, Alnajjar, Yassmeen I., Vandenput, Liesbeth, Liu, Enwu, Lorentzon, Mattias, Harvey, Nicholas C., McCloskey, Eugene V., Johansson, Helena, Kanis, John A. and the Saudi FRAX Study Group. (2022). Incidence of hip fracture in Saudi Arabia and the development of a FRAX model. Archives of Osteoporosis. 17(1), p. Article 56. https://doi.org/10.1007/s11657-022-01085-x

Journal article

Epidemiology of hip fracture in Qatar and development of a country specific FRAX model
Abdulla, Nabeel, Alsaed, Omar Suhail, Lutf, Abdo, Alam, Fiaz, Abdulmomen, Ibrahim, Al Emadi, Samar, Harvey, Nicholas C., Liu, Enwu, Vandenput, Liesbeth, Lorentzon, Mattias, McCloskey, Eugene, Kanis, John A. and Johansson, Helena. (2022). Epidemiology of hip fracture in Qatar and development of a country specific FRAX model. Archives of Osteoporosis. 17(1), p. Article 49. https://doi.org/10.1007/s11657-022-01083-z

Journal article

Development of a novel method to measure bone marrow fat fraction in older women using high-resolution peripheral quantitative computed tomography
Flehr, Alison, Källgård, Julius, Alvén, Jennifer, Lagerstrand, Kerstin, Papalini, Evin, Wheeler, Michael, Vandenput, Liesbeth, Kahl, Fredrik, Axelsson, Kristian F., Sundh, Daniel, Mysore, Raghunath Shirish and Lorentzon, Mattias. (2022). Development of a novel method to measure bone marrow fat fraction in older women using high-resolution peripheral quantitative computed tomography. Osteoporosis International. 33(7), pp. 1545-1556. https://doi.org/10.1007/s00198-021-06224-7

Journal article

Eating disorders are associated with increased risk of fall injury and fracture in Swedish men and women
Axelsson, K. F., Woessner, M. N., Litsne, H., Wheeler, M., Flehr, A., King, A. J., Kalén, M., Vandenput, L. and Lorentzon, M.. (2022). Eating disorders are associated with increased risk of fall injury and fracture in Swedish men and women. Osteoporosis International. 33(6), pp. 1347-1355. https://doi.org/10.1007/s00198-022-06312-2

Journal article

Osteoporosis in Europe : A compendium of country-specific reports
Willers, Carl, Norton, Nicholas, Harvey, Nicholas C., Jacobson, Trolle, Johansson, Helena, Lorentzon, Mattias, McCloskey, Eugene V., Borgström, Fredrik, Kanis, John A. and the SCOPE review panel of the IOF. (2022). Osteoporosis in Europe : A compendium of country-specific reports. Archives of Osteoporosis. 17(1), p. Article 23. https://doi.org/10.1007/s11657-021-00969-8

Journal article

Epidemiology and economic burden of osteoporosis in Greece
Makras, P., Lyritis, G. P., Rizou, S., Drakopoulou, T., Trovas, G., Willers, C., Norton, N., Harvey, N. C., Jacobson, T., Johansson, H., Lorentzon, M., McCloskey, E. V., Borgström, F. and Kanis, J. A.. (2022). Epidemiology and economic burden of osteoporosis in Greece. Archives of Osteoporosis. 17, p. Article 23. https://doi.org/10.1007/s11657-021-00969-8

Journal article

FRAX
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Lorentzon, Mattias, Liu, Enwu, Leslie, William D. and McCloskey, Eugene V.. (2022). FRAX. In In Pape, Hans-Christoph, Kates, Stephen L., Hierholzer, Christian and Bischoff-Ferrari, Heike A. (Ed.). Senior trauma patients : An integrated approach pp. 89-99 Springer. https://doi.org/10.1007/978-3-030-91483-7_10

Book chapter

The application of FRAX in Saudi Arabia
Al-Daghri, Nasser M., Sabico, Shaun, Al-Saleh, Yousef, Sulimani, Riad, Aljohani, Naji J., Sheshah, Eman, Alodhayani, Abdulaziz, Harvey, Nicholas C., Liu, Enwu, Lorentzon, Mattias, McCloskey, Eugene V., Vandenput, Liesbeth, Johansson, Helena and Kanis, John A.. (2021). The application of FRAX in Saudi Arabia. Archives of Osteoporosis. 16(1), p. Article 166. https://doi.org/10.1007/s11657-021-01024-2

Journal article

The application of FRAX in Ecuador
Gavilánez, Enrique López, Johansson, Helena, Harvey, Nicholas, Lorentzon, Mattias, McCloskey, Eugene, Jara, Judith Valdivieso and Kanis, John A.. (2023). The application of FRAX in Ecuador. Revista Colombiana de Reumatologia. 30(3), pp. 199-206. https://doi.org/10.1016/j.rcreu.2021.07.004

Journal article

One leg standing time predicts fracture risk in older women independent of clinical risk factors and BMD
Larsson, B. A. M., Johansson, L., Mellström, D., Johansson, H., Axelsson, K. F., Harvey, N., Vandenput, L., McCloskey, E., Liu, E., Sundh, D, Kanis, J. A. and Lorentzon, M.. (2022). One leg standing time predicts fracture risk in older women independent of clinical risk factors and BMD. Osteoporosis International. 33(1), pp. 185-194. https://doi.org/10.1007/s00198-021-06039-6

Journal article

Fractures and fall injuries after hospitalization for seasonal influenza—a national retrospective cohort study
Axelsson, K. F., Litsne, H. and Lorentzon, M.. (2021). Fractures and fall injuries after hospitalization for seasonal influenza—a national retrospective cohort study. Osteoporosis International. 33(1), pp. 47-56. https://doi.org/10.1007/s00198-021-06068-1

Journal article

FRAX-based intervention thresholds for Pakistan
Johansson, H., Naureen, G., Iqbal, R., Jafri, L., Khan, A. H., Umer, M., Liu, E., Vandenput, L., Lorentzon, M., McCloskey, E. V., Kanis, J. A. and Harvey, N. C.. (2021). FRAX-based intervention thresholds for Pakistan. Osteoporosis International. 33(1), pp. 105-112. https://doi.org/10.1007/s00198-021-06087-y

Journal article

RSPO3 is important for trabecular bone and fracture risk in mice and humans
Nilsson, Karin H., Henning, Petra, El Shahawy, Maha, Nethander, Maria, Andersen, Thomas, Ejersted, Charlotte, Wu, Jianyao, Gustafsson, Karin, Koskela, Antti, Tuukkanen, Juha, Souza, Pedro, Tuckermann, Jan, Lorentzon, Karl Mattias, Ruud, Linda, Lehtimaki, Terho, Tobias, Jon, Zhou, Sirui, Lerner, Ulf H., Richards, J. Brent, ... Ohlsson, Claes. (2021). RSPO3 is important for trabecular bone and fracture risk in mice and humans. Nature Communications. 12(1), p. Article: 4923. https://doi.org/10.1038/s41467-021-25124-2

Journal article

The challenge of applying digital image processing software on intraoral radiographs for osteoporosis risk assessment
Gullberg, Joanna, Al-Okshi, Ayman, Homar Asan, Dalia, Zainea, Anita, Sundh, Daniel, Lorentzon, Mattias and Lindh, Christina. (2021). The challenge of applying digital image processing software on intraoral radiographs for osteoporosis risk assessment. Dentomaxillofacial Radiology. 50, p. Article 20210175. https://doi.org/10.1259/dmfr.20210175

Journal article

Fracture risk assessment by the FRAX model
McCloskey, E. V., Harvey, N. C., Johansson, H., Lorentzon, M., Liu, E., Vandenput, L., Leslie, W. D. and Kanis, J. A.. (2021). Fracture risk assessment by the FRAX model. Climacteric. 25(1), pp. 22-28. https://doi.org/10.1080/13697137.2021.1945027

Journal article

Serum glycine levels are associated with cortical bone properties and fractures risk in men
Eriksson, Anna L., Friedrich, Nele, Karlsson, Magnus K., Ljunggren, Osten, Lorentzon, Mattias, Nethander, Maria, Wallaschofski, Henri, Mellstrom, Dan and Ohlsson, Claes. (2021). Serum glycine levels are associated with cortical bone properties and fractures risk in men. The Journal of Clinical Endocrinology and Metabolism. 106(12), pp. e5021-e5029. https://doi.org/10.1210/clinem/dgab544

Journal article

Factors associated with changes involumetric bone mineral density andcortical area in men with ankylosing spondylitis : A 5‑year prospective studyusing HRpQCT.
Deminger, A., Klingberg, E., Lorentzon, M., Hedberg, M., Carlsten, H., Jacobsson, L.T.H. and Forsblad-d'Elia, H.. (2022). Factors associated with changes involumetric bone mineral density andcortical area in men with ankylosing spondylitis : A 5‑year prospective studyusing HRpQCT. Osteoporosis International. 33(1), pp. 205-216. https://doi.org/10.1007/s00198-021-06049-4

Journal article

FRAX-based intervention thresholds for osteoporosis treatment in Ukraine
Povoroznyuk, Vladyslav, Grygorieva, Nataliia, Johansson, Helena, Lorentzon, Mattias, Harvey, Nicholas C., McCloskey, Eugene V., Musienko, Anna, Liu, Enwu, Kanis, John A., Zaverukha, Nataliia and Ivanyk, Oksana. (2021). FRAX-based intervention thresholds for osteoporosis treatment in Ukraine. Journal of Osteoporosis. 2021, p. Article 2043479. https://doi.org/10.1155/2021/2043479

Journal article

SCOPE 2021 : A new scorecard for osteoporosis in Europe
Kanis, John A., Norton, Nicholas, Harvey, Nicholas C., Jacobson, Trolle, Johansson, Helena, Lorentzon, Mattias, McCloskey, Eugene V., Willers, Carl and Borgström, Fredrik. (2021). SCOPE 2021 : A new scorecard for osteoporosis in Europe. Archives of Osteoporosis. 16(1), p. Article 82. https://doi.org/10.1007/s11657-020-00871-9

Journal article

Subclinical hyperthyroidism is associated with increased risk of vertebral fractures in older men
Svensson, J., Ohlsson, C., Karlsson, M. K., Lorentzon, M., Lewerin, C. and Mellstrom, D.. (2021). Subclinical hyperthyroidism is associated with increased risk of vertebral fractures in older men. Osteoporosis International. 32, pp. 2257-2265. https://doi.org/10.1007/s00198-021-05964-w

Journal article

Physical exercise is associated with beneficial bone mineral density and body composition in young adults with childhood-onset inflammatory bowel disease
Sigurdsson, Gudmundur Vignir, Schmidt, Susanne, Mellström, Dan, Ohlsson, Claes, Karlsson, Magnus, Lorentzon, Mattias and Saalman, Robert. (2021). Physical exercise is associated with beneficial bone mineral density and body composition in young adults with childhood-onset inflammatory bowel disease. Scandinavian Journal of Gastroenterology. 56(6), pp. 699-707. https://doi.org/10.1080/00365521.2021.1913759

Journal article

The Importance and Possible Clinical Impact of Measuring Trabecular and Cortical Bone Microstructure to Improve Fracture Risk Prediction
Mattias Lorentzon. (2020). The Importance and Possible Clinical Impact of Measuring Trabecular and Cortical Bone Microstructure to Improve Fracture Risk Prediction. Journal of Bone and Mineral Research. 35(5), pp. 831-832. https://doi.org/10.1002/jbmr.3940

Journal article

Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis
Mattias Lorentzon, Jaime Branco, Maria Luisa Brandi, Olivier Bruyere, Roland D Chapurlat, Cyrus Cooper, Bernard Cortet, Aldolfo Diez-Perez, Serge L Ferrari, Andrea Ildiko Gasparik, Markus Herrmann, N. R. Jorgensen, John Kanis, Jean-Marc Kaufman, A. Laslop, Medea Locquet, Radmila Matijevic, Eugene McCloskey, Salvatore Minisola, ... Etienne Cavalier. (2019). Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis. Advances in Therapy. 36(10), pp. 2811-2824. https://doi.org/10.1007/s12325-019-01063-9

Journal article

Short time horizons for fracture prediction tools : Time for a rethink
McCloskey, E. V., Borgstrom, F., Cooper, C., Harvey, N. C., Javaid, M. K., Lorentzon, M. and Kanis, J. A.. (2021). Short time horizons for fracture prediction tools : Time for a rethink. Osteoporosis International. 32(6), pp. 1019-1025. https://doi.org/10.1007/s00198-021-05962-y

Journal article

Low 25-OH vitamin d is associated with benign prostatic hyperplasia
Haghsheno, Mohammad-Ali, Mellström, Dan, Behre, Carl-Johan, Damber, Jan-Erik, Johansson, Helena, Karlsson, Magnus, Lorentzon, Mattias, Peeker, Ralph, Barret-Connor, Elisabet, Waern, Ewa, Sundh, Valter, Ohlsson, Claes and Hammarsten, Jan. (2013). Low 25-OH vitamin d is associated with benign prostatic hyperplasia. 190(2), pp. 608-614. https://doi.org/10.1016/j.juro.2013.01.104

Journal article

Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures
John Kanis, Nicholas C. Harvey, Eugene McCloskey, Olivier Bruyere, N. Veronese, Mattias Lorentzon, C. Cooper, Rene Rizzoli, G. Adib, Nasser M. Al-Daghri, C. Campusano, Manju Chandran, Bess Dawson-Hughes, M. K. Javaid, F. Jiwa, Helena Johansson, J K Lee, Enwu Liu, D Messina, ... Jean Yves Reginster. (2020). Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Osteoporosis International. 31, pp. 1-12. https://doi.org/10.1007/s00198-019-05176-3

Journal article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
Estrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Duncan, Emma L., Ntzani, Evangelia E., Oei, Ling, Albagha, Omar M. E., Amin, Najaf, Kemp, John P., Koller, Daniel L., Li, Guo, Liu, Ching-Ti, Minster, Ryan L., Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Yerges-Armstrong, Laura M., ... Rivadeneira, Fernando. (2012). Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics. 44(5), pp. 491-503. https://doi.org/10.1038/ng.2249

Journal article

Sarcopenia definitions as predictors of fracture risk independent of FRAX®, falls, and BMD in the Osteoporotic Fractures in Men (MrOS) Study : A meta-analysis
Harvey, Nicholas C., Orwoll, Eric, Kwok, Timothy, Karlsson, Magnus K., Rosengren, Björn E., Ribom, Eva, Cauley, Jane A., Cawthon, Peggy M., Ensrud, Kristine, Liu, Enwu, Cruz-Jentoft, Alfonso J., Fielding, Roger A., Cooper, Cyrus, Kanis, John A., Lorentzon, Mattias, Ohlsson, Claes, Mellström, Dan, Johansson, Helena and McCloskey, Eugene. (2021). Sarcopenia definitions as predictors of fracture risk independent of FRAX®, falls, and BMD in the Osteoporotic Fractures in Men (MrOS) Study : A meta-analysis. Journal of Bone and Mineral Research. 36(7), pp. 1235-1244. https://doi.org/10.1002/jbmr.4293

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An assessment of intervention thresholds for very high fracture risk applied to the NOGG guidelines : A report for the National Osteoporosis Guideline Group (NOGG)
Kanis, J. A., Johansson, H., Harvey, N. C., Lorentzon, M., Liu, E., Vandenput, L. and McCloskey, E. V.. (2021). An assessment of intervention thresholds for very high fracture risk applied to the NOGG guidelines : A report for the National Osteoporosis Guideline Group (NOGG). Osteoporosis International. 32, pp. 1951-1960. https://doi.org/10.1007/s00198-021-05942-2

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Intermediate monocytes correlate with CXCR3+ Th17 cells but not with bone characteristics in untreated early rheumatoid arthritis
Drevinge, Christina, Scheffler, Julia M., Koro-Arvidsson, Catalin, Sundh, Daniel, Carlsten, Hans, Gjertsson, Inger, Lindholm, Catharina, Lorentzon, Mattias, Rudin, Anna, Ekwall, Anna-Karin Hultgård and Islander, Ulrika. (2021). Intermediate monocytes correlate with CXCR3+ Th17 cells but not with bone characteristics in untreated early rheumatoid arthritis. PLoS ONE. 16(3), p. e0249205. https://doi.org/10.1371/journal.pone.0249205

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Impact of population-based or targeted BMD interventions on fracture incidence
Harvey, N. C., Kanis, J. A., Liu, E., Vandenput, L., Lorentzon, M., Cooper, C, McCloskey, E. and Johansson, H.. (2021). Impact of population-based or targeted BMD interventions on fracture incidence. Osteoporosis International. 32(10), pp. 1973-1979. https://doi.org/10.1007/s00198-021-05917-3

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Designing an Iran FRAX model and defining intervention and assessment thresholds for osteoporosis
Khashayar, P., Keshtkar, A., Ostovar, A., Larijani, B., Johansson, H., Harvey, N, Lorentzon, M., McCloskey, U. and Kanis, J.. (2021). Designing an Iran FRAX model and defining intervention and assessment thresholds for osteoporosis. Iranian Journal of Epidemiology. 16(4), pp. 296-304.

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FRAX-based fracture probabilities in South Africa
Johansson, Helena, Dela, Sapna S., Cassim, Bilkish, Paruk, Farhanah, Brown, Susan L., Conradie, Magda, Harvey, Nicholas C., Jordaan, Johannes D., Kalla, Asgar A., Liu, Enwu, Lorentzon, Mattias, Lukhele, Mkhululi, McCloskey, Eugene V., Mohamed, Ozayr, Chutterpaul, Pariva, Vandenput, Liesbeth and Kanis, John A.. (2021). FRAX-based fracture probabilities in South Africa. Archives of Osteoporosis. 16(1), p. 51. https://doi.org/10.1007/s11657-021-00905-w

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A surrogate FRAX model for Pakistan
Naureen, G., Johansson, H., Iqbal, R., Jafri, L., Khan, A. H., Umer, M., Liu, E., Vandenput, L., Lorentzon, M., Harvey, N. C., McCloskey, E. V. and Kanis, J. A.. (2021). A surrogate FRAX model for Pakistan. Archives of Osteoporosis. 16, p. 34. https://doi.org/10.1007/s11657-021-00894-w

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Metabolic alterations in older women with low bone mineral density supplemented with lactobacillus reuteri
Li, Peishun, Sundh, Daniel, Ji, Boyang, Lappa, Dimitra, Ye, Lingqun, Nielsen, Jens and Lorentzon, Mattias. (2021). Metabolic alterations in older women with low bone mineral density supplemented with lactobacillus reuteri. JBMR Plus. 5(4), p. e10478. https://doi.org/10.1002/jbm4.10478

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The effect on subsequent fracture risk of age, sex, and prior fracture site by recency of prior fracture
Kanis, J. A., Johansson, H., Harvey, N. C., Gudnason, V., Sigurdsson, G., Siggeirsdottir, K., Lorentzon, M., Liu, E., Vandenput, L. and McCloskey, E. V.. (2021). The effect on subsequent fracture risk of age, sex, and prior fracture site by recency of prior fracture. Osteoporosis International. 32(8), pp. 1547-1555. https://doi.org/10.1007/s00198-020-05803-4

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Romosozumab efficacy on fracture outcomes is greater in patients at high baseline fracture risk : A post hoc analysis of the first year of the frame study
McCloskey, E. V., Johansson, H., Harvey, N. C., Lorentzon, K., Shi, Y. and Kanis, J. A.. (2021). Romosozumab efficacy on fracture outcomes is greater in patients at high baseline fracture risk : A post hoc analysis of the first year of the frame study. Osteoporosis International. 32(8), pp. 1601-1608. https://doi.org/10.1007/s00198-020-05815-0

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Cost-effectiveness of romosozumab for the treatment of postmenopausal women with severe osteoporosis at high risk of fracture in Sweden
Söreskog, E., Lindberg, I., Kanis, J. A., Åkesson, K. E., Willems, D., Lorentzon, M., Ström, O., Berling, P. and Borgström, F.. (2021). Cost-effectiveness of romosozumab for the treatment of postmenopausal women with severe osteoporosis at high risk of fracture in Sweden. Osteoporosis International. 32, pp. 585-594. https://doi.org/10.1007/s00198-020-05780-8

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Ukranian FRAX version in the male osteoporosis management
Povoroznyuk, V, Johansson, Helena, Grygorieva, N, Kanis, John Anthony, Musiienko, A, Lorentzon, Karl Mattias, Harvey, N, McCloskey, E and Liu, Enwu. (2021). Ukranian FRAX version in the male osteoporosis management. Bol', Sustavy, Pozvonochnik (Pain, Joints, Spine). 11(2), pp. 53-61. https://doi.org/10.22141/2224-1507.11.2.2021.236563

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High platelet count is associated with low bone mineral density : The MrOS Sweden cohort
Kristjansdottir, H. L., Mellström, D., Johansson, P., Karlsson, M., Vandenput, L., Lorentzon, M., Herlitz, H., Ohlsson, C., Lerner, U. H. and Lewerin, C.. (2021). High platelet count is associated with low bone mineral density : The MrOS Sweden cohort. Osteoporosis International. 32, pp. 865-871. https://doi.org/10.1007/s00198-020-05766-6

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Low-level cadmium exposure is associated with decreased cortical thickness, cortical area and trabecular bone volume fraction in elderly men : The MrOS Sweden study
Wallin, Maria, Barregard, Lars, Sallsten, Gerd, Lundh, Thomas, Sundh, Daniel, Lorentzon, Mattias, Ohlsson, Claes and Mellström, Dan. (2021). Low-level cadmium exposure is associated with decreased cortical thickness, cortical area and trabecular bone volume fraction in elderly men : The MrOS Sweden study. Bone. 143, p. 115768. https://doi.org/10.1016/j.bone.2020.115768

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Combining fracture outcomes in phase 3 trials of osteoporosis : An analysis of the effects of denosumab in postmenopausal women
Kanis, J. A., Harvey, N. C., Lorentzon, M., Liu, E., Vandenput, L., McCloskey, E. V. and Johansson, H.. (2021). Combining fracture outcomes in phase 3 trials of osteoporosis : An analysis of the effects of denosumab in postmenopausal women. Osteoporosis International. 32(1), pp. 165-171. https://doi.org/10.1007/s00198-020-05699-0

Journal article

The timed up and go test predicts fracture risk in older women independently of clinical risk factors and bone mineral density
Larsson, B. A. M., Johansson, L., Johansson, H., Axelsson, K. F., Harvey, N., Vandenput, L., Magnusson, P., McCloskey, E., Liu, E., Kanis, J. A., Sundh, D. and Lorentzon, M.. (2021). The timed up and go test predicts fracture risk in older women independently of clinical risk factors and bone mineral density. Osteoporosis International. 32(1), pp. 75-84. https://doi.org/10.1007/s00198-020-05681-w

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The use of 2-, 5-, and 10-year probabilities to characterize fracture risk after a recent sentinel fracture
Kanis, J. A., Johansson, H., Harvey, N. C., Gudnason, V., Sigurdsson, G., Siggeirsdottir, K., Lorentzon, M., Liu, E., Vandenput, L., Leslie, W. D. and McCloskey, E. V.. (2021). The use of 2-, 5-, and 10-year probabilities to characterize fracture risk after a recent sentinel fracture. Osteoporosis International. 32(1), pp. 47-54. https://doi.org/10.1007/s00198-020-05700-w

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FRAX and ethnicity
Kanis, J. A., Cooper, C., Dawson-Hughes, B., Harvey, N. C., Johansson, H., Lorentzon, M., McCloskey, E. V., Reginster, J. Y., Rizzoli, R. and International Osteoporosis Foundation. (2020). FRAX and ethnicity. Osteoporosis International. 31(11), pp. 2063-2067. https://doi.org/10.1007/s00198-020-05631-6

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Grade 1 vertebral fractures identified by densitometric lateral spine imaging predict incident major osteoporotic fracture independently of clinical risk factors and bone mineral density in older women
Johansson, Lisa, Sundh, Daniel, Magnusson, Per, Rukmangatharajan, Komagal, Mellström, Dan, Nilsson, Anna G. and Lorentzon, Mattias. (2020). Grade 1 vertebral fractures identified by densitometric lateral spine imaging predict incident major osteoporotic fracture independently of clinical risk factors and bone mineral density in older women. Journal of Bone and Mineral Research. 35(10), pp. 1942-1951. https://doi.org/10.1002/jbmr.4108

Journal article

Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures
Kanis, J. A., Johansson, H., Harvey, N. C., Gudnason, V., Sigurdsson, G., Siggeirsdottir, K., Lorentzon, M., Liu, E., Vandenput, L. and McCloskey, E. V.. (2020). Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures. Osteoporosis International. 31(10), pp. 1817-1828. https://doi.org/10.1007/s00198-020-05517-7

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A surrogate FRAX model for the Kyrgyz Republic
Lesnyak, O., Zakroyeva, A., Lobanchenko, O., Johansson, H., Liu, E., Lorentzon, M., Harvey, N. C., McCloskey, E. and Kanis, J. A.. (2020). A surrogate FRAX model for the Kyrgyz Republic. Archives of Osteoporosis. 15, pp. 1-5. https://doi.org/10.1007/s11657-020-00743-2

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Fragility fractures in Europe : Burden, management and opportunities 
Borgström, Fredrik, Karlsson, Linda, Ortsäter, Gustav, Norton, Nicolas, Halbout, Philippe, Cooper, Cyrus, Lorentzon, Mattias, McCloskey, Eugene V., Harvey, Nicholas C., Javaid, Muhamamd K., Kanis, John A. and International Osteoporosis Foundation. (2020). Fragility fractures in Europe : Burden, management and opportunities . Archives of Osteoporosis. 15(59), pp. 1-21. https://doi.org/10.1007/s11657-020-0706-y

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Association between recurrent fracture risk and implementation of fracture liaison services in four Swedish hospitals : A cohort study
Axelsson, Kristian F., Johansson, Helena, Lundh, Dan, Möller, Michael and Lorentzon, Mattias. (2020). Association between recurrent fracture risk and implementation of fracture liaison services in four Swedish hospitals : A cohort study. The Lancet Diabetes & Endocrinology. 35(7), pp. 1216-1223. https://doi.org/10.1002/jbmr.3990

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Epidemiology of osteoporotic fracture in Kazakhstan and development of a country specific FRAX model
Issayeva, S., Lesnyak, O., Zakroyeva, A., Issayeva, B., Dilmanova, D., Johansson, H., Liu, E., Lorentzon, M., Harvey, N. C., McCloskey, E. and Kanis, J. A.. (2020). Epidemiology of osteoporotic fracture in Kazakhstan and development of a country specific FRAX model. Archives of Osteoporosis. 15, pp. 1-8. https://doi.org/10.1007/s11657-020-0701-3

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BMD-related genetic risk scores predict site-specific fractures as well as trabecular and cortical bone microstructure
Nethander, Maria, Pettersson-Kymmer, Ulrika, Vandenput, Liesbeth, Lorentzon, Mattias, Karlsson, Magnus, Mellström, Dan and Ohlsson, Claes. (2020). BMD-related genetic risk scores predict site-specific fractures as well as trabecular and cortical bone microstructure. The Journal of Clinical Endocrinology and Metabolism. 105(4), pp. e1344-e1357. https://doi.org/10.1210/clinem/dgaa082

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Epidemiology of hip fractures in Bulgaria: Development of a country-specific FRAX model
Kirilova, E., Johansson, H., Kirilov, N., Vladeva, S., Petranova, T., Kolarov, Z., Liu, E., Lorentzon, M., Vandenput, L., Harvey, N. C., McCloskey, E. and Kanis, John A.. (2020). Epidemiology of hip fractures in Bulgaria: Development of a country-specific FRAX model. Archives of Osteoporosis. 15(28), pp. 1 - 7. https://doi.org/10.1007/s11657-020-0710-2

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A decade of FRAX: How has it changed the management of osteoporosis?
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Liu, Enwu, Vandenput, Liesbeth, Lorentzon, Mattias, Leslie, William D. and McCloskey, Eugene V.. (2020). A decade of FRAX: How has it changed the management of osteoporosis? Aging Clinical and Experimental Research. 32(2), pp. 187 - 196. https://doi.org/10.1007/s40520-019-01432-y

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Use of age-dependent FRAX-based intervention thresholds for Singapore
Kanis, John A., Chandran, Manju, Chionh, Siok Bee, Ganeson, Ganga, Harvey, Nicholas C., Koh, Woon-Puay, Kwok, Timothy, Lau, Tang Ching, Liu, Enwu, Lorentzon, Mattias, McCloskey, Eugene V., Tan, Kelvin Bryan, Vandenput, Liesbeth and Johansson, Helena. (2020). Use of age-dependent FRAX-based intervention thresholds for Singapore. Archives of Osteoporosis. 15, pp. 1 - 10. https://doi.org/10.1007/s11657-020-00782-9

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Physical function tests predict incident falls: A prospective study of 2969 men in the Swedish Osteoporotic Fractures in Men study
Coster, Marcus E., Karlsson, Magnus, Ohlsson, Claes, Mellstrom, Dan, Lorentzon, Mattias, Ribom, Eva and Rosengren, Bjorn. (2020). Physical function tests predict incident falls: A prospective study of 2969 men in the Swedish Osteoporotic Fractures in Men study. Scandinavian Journal of Public Health. 48(4), pp. 436 - 441. https://doi.org/10.1177/1403494818801628

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High plasma erythropoietin predicts incident fractures in elderly men with normal renal function: The MrOS Sweden cohort
Kristjansdottir, Hallgerdur Lind, Lewerin, Catharina, Lerner, Ulf H., Herlitz, Hans, Johansson, Peter, Johansson, Helena, Karlsson, Magnus, Lorentzon, Mattias, Ohlsson, Claes, Ljunggren, Östen and Mellstrom, Dan. (2020). High plasma erythropoietin predicts incident fractures in elderly men with normal renal function: The MrOS Sweden cohort. Journal of Bone and Mineral Research. 35(2), pp. 298 - 305. https://doi.org/10.1002/jbmr.3900

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Risk for hip fracture before and after total knee replacement in Sweden
Vala, C. H., Kärrholm, J., Kanis, J. A., Johansson, H., Sten, S., Sundh, V., Karlsson, M., Lorentzon, M. and Mellström, D.. (2020). Risk for hip fracture before and after total knee replacement in Sweden. Osteoporosis International. 31(5), pp. 887-895. https://doi.org/10.1007/s00198-019-05241-x

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Increased risk for hip fracture after death of a spouse - further support for bereavement frailty?
Vala, C. H., Lorentzon, M., Sundh, V., Johansson, H., Lewerin, C., Sten, S., Karlsson, M., Ohlsson, C., Johansson, B., Kanis, J. A. and Mellström, D.. (2020). Increased risk for hip fracture after death of a spouse - further support for bereavement frailty? Osteoporosis International. 31, pp. 485-492. https://doi.org/10.1007/s00198-019-05242-w

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Secondary fracture prevention : Consensus clinical recommendations from a multistakeholder coalition
Conley, Robert B., Adib, Gemma, Adler, Robert A., Åkesson, Kristina E., Alexander, Ivy M., Amenta, Kelly C., Blank, Robert D., Brox, William Timothy, Carmody, Emily E., Chapman-Novakofski, Karen, Clarke, Bart L., Cody, Kathleen M., Cooper, Cyrus, Crandall, Carolyn J., Dirschl, Douglas R., Eagen, Thomas J., Elderkin, Ann L., Fujita, Masaki, Greenspan, Susan L., ... Kiel, Douglas P.. (2020). Secondary fracture prevention : Consensus clinical recommendations from a multistakeholder coalition. Journal of Bone and Mineral Research. 35(1), pp. 36-52. https://doi.org/10.1002/jbmr.3877

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Incidence of myocardial infarction and associated mortality varies by latitude and season : Findings from a Swedish Registry Study
Harvey, Nicholas C., Lorentzon, Mattias, Kanis, John A., McCloskey, Eugene and Johansson, Helena. (2020). Incidence of myocardial infarction and associated mortality varies by latitude and season : Findings from a Swedish Registry Study. Journal of Public Health. 42(4), pp. e440-e448. https://doi.org/10.1093/pubmed/fdz131

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FRAX-based intervention and assessment thresholds for osteoporosis in Iran
Khashayar, P., Keshtkar, A., Ostovar, A., Larijani, B., Johansson, H., Harvey, N. C., Lorentzon, M., McCloskey, E. and Kanis, John A.. (2019). FRAX-based intervention and assessment thresholds for osteoporosis in Iran. Osteoporosis International. 30, pp. 2225-2230. https://doi.org/10.1007/s00198-019-05078-4

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Disentangling the genetics of lean mass
Karasik, David, Zillikens, M. Carola, Hsu, Yi Hsiang, Aghdassi, Ali, Åkesson, Kristina, Amin, Najaf, Barroso, Inês, Bennett, David A., Bertram, Lars, Bochud, Murielle, Borecki, Ingrid, Broer, Linda, Buchman, Aron S., Byberg, Liisa, Campbell, Harry, Campos-Obando, Natalia, Cauley, Jane, Cawthon, Peggy M, Chambers, John, ... Ohlsson, Claes. (2019). Disentangling the genetics of lean mass. American Journal of Clinical Nutrition. 109(2), pp. 276-278. https://doi.org/10.1093/ajcn/nqy272

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Treating osteoporosis to prevent fractures: Current concepts and future developments
Lorentzon, Mattias. (2019). Treating osteoporosis to prevent fractures: Current concepts and future developments. Journal of Internal Medicine. 285(4), pp. 381 - 394. https://doi.org/10.1111/joim.12873

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Mendelian randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures
Zheng, Jie, Maerz, Winfried, Gergei, Ingrid, Kleber, Marcus E., Drechsler, Christiane, Wanner, Christoph, Brandenburg, Vincent, Reppe, Sjur, Gautvik, Kaare M., Medina-Gomez, Carolina, Shevroja, Enisa, Gilly, Arthur, Park, Young-Chan, Dedoussis, George, Zeggini, Eleftheria, Lorentzon, Mattias, Henning, Petra, Lerner, Ulf H., Nilsson, Karin H., ... Tobias, Jonathan H.. (2019). Mendelian randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures. Journal of Bone and Mineral Research. 34(10), pp. 1824 - 1836. https://doi.org/10.1002/jbmr.3803

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Extensive undertreatment of osteoporosis in older Swedish women
Lorentzon, Mattias, Nilsson, A. G., Johansson, Helena, Kanis, John A., Mellström, Dan and Sundh, D.. (2019). Extensive undertreatment of osteoporosis in older Swedish women. Osteoporosis International. 30(6), pp. 1297 - 1305. https://doi.org/10.1007/s00198-019-04872-4

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Appendicular lean mass and fracture risk assessment: Implications for FRAX(R) and sarcopenia
Harvey, Nicholas C., Kanis, John A., Liu, Enwu, Johansson, Helena, Lorentzon, Mattias and McCloskey, Eugene. (2019). Appendicular lean mass and fracture risk assessment: Implications for FRAX(R) and sarcopenia. Osteoporosis International. 30(3), pp. 537 - 539. https://doi.org/10.1007/s00198-019-04904-z

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Temporal changes in access to FRAX in Thailand between 2010 and 2018
Chotiyarnwong, Pojchong, Harvey, Nicholas C., Johansson, Helena, Liu, Enwu, Lorentzon, Mattias, Kanis, John A. and McCloskey, Eugene V.. (2019). Temporal changes in access to FRAX in Thailand between 2010 and 2018. Archives of Osteoporosis. 14(1), pp. 1 - 7. https://doi.org/10.1007/s11657-019-0613-2

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Patients with prostate cancer and androgen deprivation therapy have increased risk of fractures—a study from the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO)
Wallander, M., Axelsson, K. F., Lundh, D. and Lorentzon, Mattias. (2019). Patients with prostate cancer and androgen deprivation therapy have increased risk of fractures—a study from the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO). Osteoporosis International. 30(1), pp. 115 - 125. https://doi.org/10.1007/s00198-018-4722-3

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Decreased physical health-related quality of life—a persisting state for older women with clinical vertebral fracture
Johansson, L., Svensson, H. K., Karlsson, J., Olsson, L. E., Mellström, Dan, Lorentzon, Mattias and Sundh, D.. (2019). Decreased physical health-related quality of life—a persisting state for older women with clinical vertebral fracture. Osteoporosis International. 30, pp. 1961 - 1971. https://doi.org/10.1007/s00198-019-05044-0

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Meta-analysis of genomewide association studies reveals genetic variants for hip bone geometry
Hsu, Yi-Hsiang, Estrada, Karol, Evangelou, Evangelos, Ackert-Bicknell, Cheryl, Åkesson, Kristina, Beck, Thomas, Brown, Suzanne J., Capellini, Terence, Carbone, Laura, Cauley, Jane, Cheung, Ching-Lung, Cummings, Steven R., Czerwinski, Stefan, Demissie, Serkalem, Econs, Michael J., Evans, Daniel S., Farber, Charles, Gautvik, Kaare M., Harris, Tamara, ... Karasik, David. (2019). Meta-analysis of genomewide association studies reveals genetic variants for hip bone geometry. Journal of Bone and Mineral Research. 34(7), pp. 1284 - 1296. https://doi.org/10.1002/jbmr.3698

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Association between cortical bone microstructure and statin use in older women
Larsson, Berit A. M., Sundh, Daniel, Mellström, Dan, Axelsson, Kristian F., Nilsson, Anna G. and Lorentzon, Mattias. (2019). Association between cortical bone microstructure and statin use in older women. The Journal of Clinical Endocrinology and Metabolism. 104(2), pp. 250 - 257. https://doi.org/10.1210/jc.2018-02054

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Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC) : A prospective study
Samelson, Elizabeth J., Broe, Kerry E., Xu, Hanfei, Yang, Laiji, Boyd, Steven, Biver, Emmanuel, Szulc, Pawel, Adachi, Jonathan, Amin, Shreyasee, Atkinson, Elizabeth, Berger, Claudie, Burt, Lauren, Chapurlat, Roland, Chevalley, Thierry, Ferrari, Serge, Goltzman, David, Hanley, David A., Hannan, Marian T., Khosla, Sundeep, ... Bouxsein, Mary L.. (2019). Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC) : A prospective study. The Lancet Diabetes & Endocrinology. 7(1), pp. 34-43. https://doi.org/10.1016/S2213-8587(18)30308-5

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Genome analyses of > 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders
Vaez, Ahmad, Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Prins, Bram P., Van der Most, Peter J., Tanaka, Toshiko, Naderi, Elnaz, Rose, Lynda M., Wu, Ying, Karlsson, Robert, Barbalic, Maja, Lin, Honghuang, Pool, René, Zhu, Gu, Macé, Aurélien, Sidore, Carlo, Trompet, Stella, Mangino, Massimo, ... Alizadeh, Behrooz Z.. (2018). Genome analyses of > 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders. American Journal of Human Genetics. 103(5), pp. 691-706. https://doi.org/10.1016/j.ajhg.2018.09.009

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Assessment of the genetic and clinical determinants of fracture risk: Genome wide association and mendelian randomisation study
Trajanoska, Katerina, Morris, John A., Oei, Ling, Zheng, Hou-Feng, Evans, David M., Kiel, Douglas P., Ohlsson, Claes, Richards, J. Brent, Rivadeneira, Fernando, on behalf of the GEFOS/GENOMOS consortium and the 23andMe research team*, Lorentzon, Mattias and Vandenput, Liesbeth. (2018). Assessment of the genetic and clinical determinants of fracture risk: Genome wide association and mendelian randomisation study. BMJ. 362, p. Article k3225. https://doi.org/10.1136/bmj.k3225

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Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
Jiang, Xia, O'Reilly, Paul F., Aschard, Hugues, Hsu, Yi-Hsiang, Richards, J. Brent, Dupuis, Josée, Ingelsson, Erik, Karasik, David, Pilz, Stefan, Berry, Diane, Kestenbaum, Bryan, Zheng, Jusheng, Luan, Jianan, Sofianopoulou, Eleni, Streeten, Elizabeth A., Albanes, Demetrius, Lutsey, Pamela L., Yao, Lu, Tang, Weihong, ... Lorentzon, Mattias. (2018). Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Nature Communications. 9(1), p. 260. https://doi.org/10.1038/s41467-017-02662-2

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High serum serotonin predicts increased risk for hip fracture and nonvertebral osteoporotic fractures: The MrOS Sweden Study
Kristjansdottir, Hallgerdur Lind, Lewerin, C., Lerner, Ulf H., Waern, Ewa, Johansson, Helena, Sundh, Daniel, Karlsson, Magnus, Cummings, Steven R., Zetterberg, Henrik, Lorentzon, Mattias, Ohlsson, Claes and Mellstrom, Dan. (2018). High serum serotonin predicts increased risk for hip fracture and nonvertebral osteoporotic fractures: The MrOS Sweden Study. Journal of Bone and Mineral Research. 33(9), pp. 1560 - 1567. https://doi.org/10.1002/jbmr.3443

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High-impact mechanical loading increases bone material strength in postmenopausal women—a 3-month intervention study
Sundh, Daniel, Nilsson, Martin, Zoulakis, Michail, Pasco, Courtney, Yilmaz, Melis, Kazakia, Galateia J., Hellgren, Martin and Lorentzon, Mattias. (2018). High-impact mechanical loading increases bone material strength in postmenopausal women—a 3-month intervention study. Journal of Bone and Mineral Research. 33(7), pp. 1242 - 1251. https://doi.org/10.1002/jbmr.3431

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Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: A randomized, placebo-controlled, double-blind, clinical trial
Nilsson, A. G., Sundh, D., Bäckhed, F. and Lorentzon, Mattias. (2018). Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: A randomized, placebo-controlled, double-blind, clinical trial. Journal of Internal Medicine. 284(3), pp. 307 - 317. https://doi.org/10.1111/joim.12805

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Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects
Medina-Gómez, Carolina, Kemp, John P., Trajanoska, Katerina, Luan, Jian'an, Chesi, Alessandra, Ahluwalia, Tarunveer S., Mook-Kanamori, Dennis O., Ham, Annelies C., Hartwig, Fernando P., Evans, Daniel S., Joro, Raimo, Nedeljkovic, Ivana, Zheng, Hou-Feng, Zhu, Kun, Atalay, Mustafa, Liu, Ching-Ti, Nethander, Maria, Broer, Linda, Porleifsson, Gudmar, ... Rivadeneira, Fernando. (2018). Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects. American Journal of Human Genetics. 102(1), pp. 88 - 102. https://doi.org/10.1016/j.ajhg.2017.12.005

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Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers
Johansson, Helena, Vala, C. H., Oden, Anders, Lorentzon, Mattias, McCloskey, Eugene, Kanis, John, Harvey, Nicholas C., Ohlsson, Claes, Lohmander, L. S., Karrholm, J. and Mellstrom, D.. (2018). Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers. Osteoporosis International. 29(3), pp. 741 - 749. https://doi.org/10.1007/s00198-017-4355-y

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The prevalence of vertebral fractures is associated with reduced hip bone density and inferior peripheral appendicular volumetric bone density and structure in older women
Johansson, Lisa, Sundh, Daniel, Zoulakis, Michael, Rudäng, Robert, Darelid, Anna, Brisby, Helena, Nilsson, Anna G., Mellström, Dan and Lorentzon, Mattias. (2018). The prevalence of vertebral fractures is associated with reduced hip bone density and inferior peripheral appendicular volumetric bone density and structure in older women. Journal of Bone and Mineral Research. 33(2), pp. 250 - 260. https://doi.org/10.1002/jbmr.3297

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Vertebral fractures and their association with health-related quality of life, back pain and physical function in older women
Johansson, Lisa, Sundh, Daniel, Nilsson, Dan, Mellström, Dan and Lorentzon, Mattias. (2018). Vertebral fractures and their association with health-related quality of life, back pain and physical function in older women. Osteoporosis International. 29(1), pp. 89 - 99. https://doi.org/10.1007/s00198-017-4296-5

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Fracture risk after gastric bypass surgery: A retrospective cohort study
Axelsson, Kristian F., Werling, Malin, Eliasson, Björn, Szabo, Eva, Näslund, Ingmar, Wedel, Hans, Lundh, Dan and Lorentzon, Mattias. (2018). Fracture risk after gastric bypass surgery: A retrospective cohort study. Journal of Bone and Mineral Research. 33(12), pp. 2122 - 2131. https://doi.org/10.1002/jbmr.3553

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Genetic determinants of circulating estrogen levels and evidence of a causal effect of estradiol on bone density in men
Eriksson, Anna L., Perry, John R. B., Coviello, Andreas D., Delgado, Graciela E., Ferrucci, Luigi, Hoffman, Andrew R., Huhtaniemi, Ilpo T., Ikram, M. Arfan, Karlsson, Magnus K., Kleber, Marcus E., Laughlin, Gail A., Liu, Yongmei, Lorentzon, Mattias, Lunetta, Kathryn L., Mellström, Dan, Murabito, Joanne M., Murray, Anna, Nethander, Maria, Nielson, Carrie M., ... Ohlsson, Claes. (2018). Genetic determinants of circulating estrogen levels and evidence of a causal effect of estradiol on bone density in men. The Journal of Clinical Endocrinology and Metabolism. 103(3), pp. 991 - 1004. https://doi.org/10.1210/jc.2017-02060

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Normal bone microstructure and density but worse physical function in older women treated with selective serotonin reuptake inhibitors, a cross-sectional population-based study
Larsson, Berit A. M., Mellström, Dan, Johansson, Lisa, Nilsson, Anna G., Lorentzon, Mattias and Sundh, Daniel. (2018). Normal bone microstructure and density but worse physical function in older women treated with selective serotonin reuptake inhibitors, a cross-sectional population-based study. Calcified Tissue International. 103(3), pp. 278 - 288. https://doi.org/10.1007/s00223-018-0427-z

Journal article

Risk factors for low back pain and sciatica in elderly men--the MrOS Sweden study
Kherad, Mehrsa, Rosengren, Björn E., Hasserius, Ralph, Nilsson, Jan-Åke, Redlund-Johnell, Inga, Ohlsson, Claes, Mellström, Dan, Lorentzon, Mattias, Ljunggren, Östen and Karlsson, Magnus K.. (2017). Risk factors for low back pain and sciatica in elderly men--the MrOS Sweden study. Age and Ageing. 46(1), pp. 64 - 71. https://doi.org/10.1093/ageing/afw152

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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Graff, Mariaelisa, Scott, Robert A., Justice, Anne E., Young, Kristin L., Feitosa, Mary F., Barata, Llilda, Winkler, Thomas W., Chu, Audrey Y., Mahajan, Anubha, Hadley, David, Xue, Luting, Workalemahu, Tsegaselassie, Heard-Costa, Nancy L., den Hoed, Marcel, Ahluwalia, Tarunveer S., Qi, bin Qi, Ngwa, Julius S., Renström, Frida, Quaye, Lydia, ... Lorentzon, Mattias. (2017). Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults. PLoS Genetics. 13(4), pp. 1 - 26. https://doi.org/10.1371/journal.pgen.1006528

Journal article

Cortical bone area predicts incident fractures independently of areal bone mineral density in older men
Ohlsson, Claes, Sundh, Daniel, Wallerek, Andreas, Nilson, Martin, Karlsson, Magnus, Johansson, Helena, Mellstrom, Dan and Lorentzon, Mattias. (2017). Cortical bone area predicts incident fractures independently of areal bone mineral density in older men. The Journal of Clinical Endocrinology and Metabolism. 102(2), pp. 516 - 524. https://doi.org/10.1210/jc.2016-3177

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Association between alendronate use and hip fracture risk in older patients using oral prednisolone
Axelsson, Kristian F., Nilsson, Anna G., Wedel, Hans, Lundh, Dan and Lorentzon, Mattias. (2017). Association between alendronate use and hip fracture risk in older patients using oral prednisolone. JAMA: Journal of the American Medical Association. 318(2), pp. 146 - 155. https://doi.org/10.1001/jama.2017.8040

Journal article

Hip fracture risk and safety with alendronate treatment in the oldest-old
Axelsson, K. F., Wallander, M., Johansson, Helena, Lundh, D. and Lorentzon, Mattias. (2017). Hip fracture risk and safety with alendronate treatment in the oldest-old. Journal of Internal Medicine. 282(6), pp. 546 - 559. https://doi.org/10.1111/joim.12678

Journal article

Type 2 diabetes and risk of hip fractures and non-skeletal fall injuries in the elderly: A study from the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO)
Wallander, Märit, Axelsson, Kristian F., Nilsson, Anna G., Lundh, Dan and Lorentzon, Mattias. (2017). Type 2 diabetes and risk of hip fractures and non-skeletal fall injuries in the elderly: A study from the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO). Journal of Bone and Mineral Research. 32(3), pp. 449 - 460. https://doi.org/10.1002/jbmr.3002

Journal article

Increased risk of hip fracture among spouses-evidence of a homogamy effect
Vala, C. H., Oden, Anders, Lorentzon, Mattias, Sundh, V., Johansson, Helena, Karlsson, Magnus, Rosengren, Björn E., Ohlsson, Claes, Johansson, B., Kanis, John and Mellström, Dan. (2017). Increased risk of hip fracture among spouses-evidence of a homogamy effect. Osteoporosis International. 28(1), pp. 95 - 102. https://doi.org/10.1007/s00198-016-3738-9

Journal article

Bone traits seem to develop also during the third decade in life—normative cross-sectional data on 1083 men aged 18–28 years
Lindgren, Erik, Karlsson, Magnus K., Lorentzon, Mattias and Rosengren, Björn E.. (2017). Bone traits seem to develop also during the third decade in life—normative cross-sectional data on 1083 men aged 18–28 years. Journal of Clinical Densitometry. 20(1), pp. 32 - 43. https://doi.org/10.1016/j.jocd.2016.07.002

Journal article

Low testosterone, but not estradiol, is associated with incident falls in older men: The international MrOS study
Vandenput, Liesbeth, Mellström, Dan, Laughlin, Gail A., Cawthon, Peggy M., Cauley, Jane A., Hoffman, Andrew R., Karlsson, Magnus K., Rosengren, Björn E., Ljunggren, Östen, Nethander, Maria, Eriksson, Anna L., Lorentzon, Mattias, Leung, Jason, Kwok, Timothy, Orwoll, Eric S. and Ohlsson, Claes. (2017). Low testosterone, but not estradiol, is associated with incident falls in older men: The international MrOS study. Journal of Bone and Mineral Research. 32(6), pp. 1174 - 1181. https://doi.org/10.1002/jbmr.3088

Journal article

Increased cortical porosity in women with hip fracture
Sundh, Daniel, Nilsson, A. G., Nilsson, Martin, Johansson, L., Mellström, Dan and Lorentzon, Mattias. (2017). Increased cortical porosity in women with hip fracture. Journal of Internal Medicine. 281(5), pp. 496 - 506. https://doi.org/10.1111/joim.12587

Journal article

Low serum iron is associated with high serum intact FGF23 in elderly men: The Swedish MrOS study
Lewerin, Catharina, Ljunggren, Östen, Nilsson-Ehle, Herman, Karlsson, Magnus K., Herlitz, Hans, Lorentzon, Mattias, Ohlsson, Claes and Mellström, Dan. (2017). Low serum iron is associated with high serum intact FGF23 in elderly men: The Swedish MrOS study. Bone. 98, pp. 1 - 8. https://doi.org/10.1016/j.bone.2017.02.005

Journal article

Low-frequency synonymous coding variation in CYP2R1 has large effects on vitamin d levels and risk of multiple sclerosis
Manousaki, Despoina, Dudding, Tom, Haworth, Simon, Hsu, Yi-Hsiang, Liu, Chiang-Ti, Medina-Gómez, Carolina, Voortman, Trudy, van der Velde, Nathalie, Melhus, Håkan, Robinson-Cohen, Cassianne, Cousminer, Diana L., Nethander, Maria, Vandenput, Liesbeth, Noordam, Raymond, Forgetta, Vincenzo, Greenwood, Celia M. T., Biggs, Mary L., Psaty, Bruce M., Rotter, Jerome I., ... Richards, J. Brent. (2017). Low-frequency synonymous coding variation in CYP2R1 has large effects on vitamin d levels and risk of multiple sclerosis. American Journal of Human Genetics. 101(2), pp. 227 - 238. https://doi.org/10.1016/j.ajhg.2017.06.014

Journal article

Type 2 diabetes mellitus is associated with better bone microarchitecture but lower bone material strength and poorer physical function in elderly women: A population-based study
Nilsson, Anna G., Sundh, Daniel, Johansson, Lisa, Nilsson, Martin, Mellström, Dan, Rudäng, Robert, Zoulakis, Michail, Wallander, Märit, Darelid, Anna and Lorentzon, Mattias. (2017). Type 2 diabetes mellitus is associated with better bone microarchitecture but lower bone material strength and poorer physical function in elderly women: A population-based study. Journal of Bone and Mineral Research. 32(5), pp. 1062 - 1071. https://doi.org/10.1002/jbmr.3057

Journal article

Bone mass development from childhood into young adulthood in patients with childhood-onset inflammatory bowel disease
Sigurdsson, Gudmundur Vignir, Schmidt, Susanne, Mellström, Dan, Ohlsson, Claes, Kindblom, Jenny M., Lorentzon, Mattias and Saalman, Robert. (2017). Bone mass development from childhood into young adulthood in patients with childhood-onset inflammatory bowel disease. Inflammatory Bowel Diseases. 23(12), pp. 2215 - 2226. https://doi.org/10.1097/MIB.0000000000001277

Journal article

Genetic variants associated with circulating parathyroid hormone
Robinson-Cohen, Cassianne, Lutsey, Pamela L., Kleber, Marcus E., Nielson, Carrie M., Mitchell, Braxton D., Bis, Joshua C., Eny, Karen M., Portas, Laura, Eriksson, Joel, Lorentzon, Mattias, Koller, Daniel L., Milaneschi, Yuri, Teumer, Alexander, Pilz, Stefan, Nethander, Maria, Selvin, Elizabeth, Tang, Weihong, Weng, Lu-Chen, Wong, Hoi Suen, ... Kestenbaum, Bryan. (2017). Genetic variants associated with circulating parathyroid hormone. Journal of the American Society of Nephrology. 28(5), pp. 1553 - 1565. https://doi.org/10.1681/ASN.2016010069

Journal article

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis
Eriksson, Joel, Haring, Robin, Grarup, Niels, Vandenput, Liesbeth, Wallaschofski, Henri, Lorentzen, Erik, Hansen, Torben, Mellström, Dan, Pedersen, Oluf, Nauck, Matthias, Lorentzon, Mattias, Husemoen, Lise Lotte Nystrup, Völzke, Henry, Karlsson, Magnus, Baumeister, Sebastian E., Linneberg, Allan and Ohlsson, Claes. (2017). Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis. PLoS ONE. 12(4), pp. 1 - 15. https://doi.org/10.1371/journal.pone.0176277

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Romosozumab or alendronate for fracture prevention in women with osteoporosis
Saag, Kenneth G., Petersen, Jeffrey, Brandi, Maria Luisa, Karaplis, Andrew C., Lorentzon, Mattias, Thomas, Thierry A., Maddox, Judy, Fan, Michelle, Meisner, Paul D. and Grauer, Andreas. (2017). Romosozumab or alendronate for fracture prevention in women with osteoporosis. New England Journal of Medicine. 377(15), pp. 1417 - 1427. https://doi.org/10.1056/NEJMoa1708322

Journal article

Low serum DHEAS predicts increased fracture risk in older men: The MrOS Sweden study
Ohlsson, Claes, Nethander, Maria, Kindmark, Andreas, Ljunggren, Östen, Lorentzon, Mattias, Rosengren, Björn E., Karlsson, Magnus K., Mellström, Dan and Vandenput, Liesbeth. (2017). Low serum DHEAS predicts increased fracture risk in older men: The MrOS Sweden study. Journal of Bone and Mineral Research. 32(8), pp. 1607 - 1614. https://doi.org/10.1002/jbmr.3123

Journal article

Current physical activity is independently associated with cortical bone size and bone strength in elderly Swedish women
Nilsson, Martin, Sundh, Daniel, Mellström, Dan and Lorentzon, Mattias. (2017). Current physical activity is independently associated with cortical bone size and bone strength in elderly Swedish women. Journal of Bone and Mineral Research. 32(3), pp. 473 - 485. https://doi.org/10.1002/jbmr.3006

Journal article

Which measuring site in ankylosing spondylitis is best to detect bone loss and what predicts the decline: results from a 5-year prospective study
Deminger, Anna, Klingberg, Eva, Lorentzon, Mattias, Geijer, Mats, Göthlin, Jan, Hedberg, Martin, Rehnberg, Eva, Carlsten, Hans, Jacobsson, Lennart T. and Forsblad-d'Elia, Helena. (2017). Which measuring site in ankylosing spondylitis is best to detect bone loss and what predicts the decline: results from a 5-year prospective study. Arthritis Research and Therapy. 19(1), pp. 1 - 12. https://doi.org/10.1186/s13075-017-1480-0

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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Justice, Anne E., Winkler, Thomas W., Feitosa, Mary F., Graff, Misa, Fisher, Virginia A., Young, Kristin L., Barata, Llilda, Deng, Xuan, Czajkowski, Jacek, Hadley, David, Ngwa, Julius S., Ahluwalia, Tarunveer S., Chu, Audrey Y., Heard-Costa, Nancy L., Lim, Elise, Perez, Jeremiah, Eicher, John D., Kutalik, Zoltán, Xue, Luting, ... Lorentzon, Mattias. (2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications. 8(1), pp. 1 - 19. https://doi.org/10.1038/ncomms14977

Journal article

The limited clinical utility of testosterone, estradiol, and sex hormone binding globulin measurements in the prediction of fracture risk and bone loss in older men
Orwoll, Eric S., Lapidus, Jodi, Wang, Patty Y., Vandenput, Liesbeth, Hoffman, Andrew, Fink, Howard A., Laughlin, Gail A., Nethander, Maria, Ljunggren, Östen, Kindmark, Andreas, Lorentzon, Mattias, Karlsson, Magnus K., Mellström, Dan, Kwok, Anthony, Khosla, Sundeep, Kwok, Timothy and Ohlsson, Claes. (2017). The limited clinical utility of testosterone, estradiol, and sex hormone binding globulin measurements in the prediction of fracture risk and bone loss in older men. Journal of Bone and Mineral Research. 32(3), pp. 633-640. https://doi.org/10.1002/jbmr.3021

Journal article

Characteristics of prevalent vertebral fractures predict new fractures in elderly men
Karlsson, Magnus K., Kherad, Mehrsa, Hasserius, Ralph, Nilsson, Jan-Åke, Redlund-Johnell, Inga, Ohlsson, Claes, Lorentzon, Mattias, Mellström, Dan and Rosengren, Björn E.. (2016). Characteristics of prevalent vertebral fractures predict new fractures in elderly men. Journal of Bone and Joint Surgery: American Volume. 98(5), pp. 379 - 385. https://doi.org/10.2106/JBJS.15.00328

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A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried, Janina S., Jeff, Janina, Chu, Audrey Y., Bragg-Gresham, Jennifer L., van Dongen, Jenny, Huffman, Jennifer E., Ahluwalia, Tarunveer S., Cadby, Gemma, Eklund, Niina, Eriksson, Joel, Esko, Tõnu, Feitosa, Mary F., Goel, Anuj, Gorski, Mathias, Hayward, Caroline, Heard-Costa, Nancy L., Jackson, Anne U., Jokinen, Eero, Kanoni, Stavroula, ... Loos, Ruth J. F.. (2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications. 7(1), pp. 1 - 11. https://doi.org/10.1038/ncomms13357

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Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Teumer, Alexander, Qi, bin Qi, Nethander, Maria, Aschard, Hugues, Bandinelli, Stefania, Beekman, Marian, Berndt, Sonja I., Bidlingmaier, Martin, Broer, Linda, Cappola, Anne, Ceda, Gian Paolo, Chanock, Stephen J., Chen, Ming-Huei, Chen, Tai C., Chen, Yii-Der, Chung, Jonathan, Del Greco Miglianico, Fabiola, Eriksson, Joel, Ferrucci, Luigi, ... Lorentzon, Mattias. (2016). Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. 15(5), pp. 811 - 824. https://doi.org/10.1111/acel.12490

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Determinants of microstructural, dimensional and bone mineral changes postpartum in Swedish women
Brembeck, Peter, Winkvist, Anna, Ohlsson, Claes, Lorentzon, Mattias and Augustin, Hanna. (2016). Determinants of microstructural, dimensional and bone mineral changes postpartum in Swedish women. The British Journal of Nutrition. 116(10), pp. 1736 - 1744. https://doi.org/10.1017/S0007114516003998

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Fall risk assessment predicts fall-related injury, hip fracture, and head injury in older adults
Nilsson, , Eriksson, Joel, Larsson, Berit A. M., Odén, Anders, Johansson, Helena and Lorentzon, Mattias. (2016). Fall risk assessment predicts fall-related injury, hip fracture, and head injury in older adults. Journal of the American Geriatrics Society. 64(11), pp. 2242 - 2250. https://doi.org/10.1111/jgs.14439

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Bone material strength is associated with areal BMD but not with prevalent fractures in older women
Rudäng, R., Zoulakis, M., Sundh, D., Brisby, H., Diez-Perez, Aldolfo, Johansson, L., Mellström, Dan, Darelid, A. and Lorentzon, Mattias. (2016). Bone material strength is associated with areal BMD but not with prevalent fractures in older women. Osteoporosis International. 27(4), pp. 1585 - 1592. https://doi.org/10.1007/s00198-015-3419-0

Journal article

High serum SHBG predicts incident vertebral fractures in elderly men
Vandenput, Liesbeth, Mellström, Dan, Kindmark, Andreas, Johansson, Helena, Lorentzon, Mattias, Leung, Jason, Redlund-Johnell, Inga, Rosengren, Björn E., Karlsson, Magnus K., Wang, Yi-Xiang, Kwok, Timothy and Ohlsson, Claes. (2016). High serum SHBG predicts incident vertebral fractures in elderly men. Journal of Bone and Mineral Research. 31(3), pp. 683 - 689. https://doi.org/10.1002/jbmr.2718

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Effectiveness of a minimal resource fracture liaison service
Axelsson, K. F., Jacobsson, R., Lund, D. and Lorentzon, Mattias. (2016). Effectiveness of a minimal resource fracture liaison service. Osteoporosis International. 27(11), pp. 3165 - 3175. https://doi.org/10.1007/s00198-016-3643-2

Journal article

High plasma osteocalcin is associated with low blood haemoglobin in elderly men: The MrOS Sweden Study
Lewerin, C., Johansson, Helena, Karlsson, Magnus K., Lorentzon, Mattias, Lerner, Ulf H., Kindblom, J. M., Ohlsson, Claes, Smith, Ulf and Mellström, Dan. (2016). High plasma osteocalcin is associated with low blood haemoglobin in elderly men: The MrOS Sweden Study. Journal of Internal Medicine. 280(4), pp. 398 - 406. https://doi.org/10.1111/joim.12505

Journal article

Low serum vitamin D is associated with higher cortical porosity in elderly men
Sundh, D., Mellström, Dan, Ljunggren, Östen, Karlsson, Magnus K., Ohlsson, Claes, Nilsson, M., Nilsson, A. G. and Lorentzon, Mattias. (2016). Low serum vitamin D is associated with higher cortical porosity in elderly men. Journal of Internal Medicine. 280(5), pp. 496 - 508. https://doi.org/10.1111/joim.12514

Journal article

A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX
McCloskey, Eugene, Oden, Anders, Harvey, Nicholas C., Leslie, William, Hans, D., Johansson, Helena, Barkmann, Reinhard, Boutroy, Stephanie, Brown, J. P., Chapurlat, Roland D., Elders, Petra J. M., Fujita, Yuki, Glüer, Claus C., Goltzman, David, Iki, Masayuki, Karlsson, M. K., Kindmark, Andreas, Kotowicz, Mark, Kurumatani, Norio, ... Kanis, John A.. (2016). A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX. Journal of Bone and Mineral Research. 31(5), pp. 940 - 948. https://doi.org/10.1002/jbmr.2734

Journal article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen, Tuomas O., Martin Carli, Jayne F., Skowronski, Alicja A., Sun, Qi, Kriebel, Jennifer, Feitosa, Mary F., Hedman, Åsa K., Drong, Alexander W., Hayes, James E., Zhao, Jinghua H., Pers, Tune H., Schick, Ursula M., Grarup, Niels, Kutalik, Zoltán, Trompet, Stella, Mangino, Massimo, Kristiansson, Kati, Beekman, Marian, Lyytikäinen, Leo-Pekka, ... Lorentzon, Mattias. (2016). Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nature Communications. 7(1), pp. 1 - 14. https://doi.org/10.1038/ncomms10494

Journal article

A high amount of local adipose tissue Is associated with high cortical porosity and low bone material strength in older women
Sundh, Daniel, Rudäng, Robert, Zoulakis, Michail, Nilsson, Anna G., Darelid, Anna and Lorentzon, Mattias. (2016). A high amount of local adipose tissue Is associated with high cortical porosity and low bone material strength in older women. Journal of Bone and Mineral Research. 31(4), pp. 749 - 757. https://doi.org/10.1002/jbmr.2747

Journal article

Low-level cadmium exposure is associated with decreased bone mineral density and increased risk of incident fractures in elderly men: The MrOS Sweden study
Wallin, Maria, Barregard, Lars, Sallsten, Gerd, Lundh, Thomas, Karlsson, Magnus K., Lorentzon, Mattias, Ohlsson, Claes and Mellström, Dan. (2016). Low-level cadmium exposure is associated with decreased bone mineral density and increased risk of incident fractures in elderly men: The MrOS Sweden study. Journal of Bone and Mineral Research. 31(4), pp. 732 - 741. https://doi.org/10.1002/jbmr.2743

Journal article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study
Winkler, T.W., Justice, A.E., Graff, M., Barata, Llilda, Feitosa, M.F., Chu, Su, Czajkowski, Jacek, Esko, T., Fall, T., Kilpeläinen, T.O., Lu, Yingchang, Mägi, R., Mihailov, E., Lorentzon, Karl Mattias, Vandenput, Liesbeth and et. al.. (2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study. PLoS Genetics. 11(10), pp. 1-42. https://doi.org/10.1371/journal.pgen.1005378

Journal article

Osteoporosis: The evolution of a diagnosis
Lorentzon, Mattias and Cummings, Steven R.. (2015). Osteoporosis: The evolution of a diagnosis. Journal of Internal Medicine. 277(6), pp. 650 - 661. https://doi.org/10.1111/joim.12369

Journal article

New genetic loci link adipose and insulin biology to body fat distribution
Shungin, Dmitry, Winkler, Thomas W., Croteau-Chonka, Damien C., Ferreira, Teresa, Locke, Adam E., Mägi, Reedik, Strawbridge, Rona J., Pers, Tune H., Fischer, Krista, Justice, Anne E., Workalemahu, Tsegaselassie, Wu, Joseph M. W., Buchkovich, Martin L., Heard-Costa, Nancy L., Roman, Tamara S., Drong, Alexander W., Song, Ci, Gustafsson, Stefan, Day, Felix R., ... Lorentzon, Mattias. (2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature. 518, pp. 187 - 196. https://doi.org/10.1038/nature14132

Journal article

Lower urinary symptoms are associated with low levels of serum serotonin, high levels of adinopectin and fasting glucose, and benign prostatic enlargement
Haghsheno, Mohammad-Ali, Mellstrom, Dan, Peeker, Ralph, Hammarsten, Jan, Lorentzon, Mattias, Sundh, Valter, Karlsson, Magnus, Ohlsson, Claes and Damber, Jan-Erik. (2015). Lower urinary symptoms are associated with low levels of serum serotonin, high levels of adinopectin and fasting glucose, and benign prostatic enlargement. Scandinavian Journal of Urology. 49(2), pp. 155 - 161. https://doi.org/10.3109/21681805.2014.936495

Journal article

The number and characteristics of prevalent vertebral fractures in elderly men are associated with low bone mass and osteoporosis
Kherad, M., Mellström, Dan, Rosengren, Björn E., Hasserius, R., Nilsson, J.-Å., Redlund-Johnell, Inga, Ohlsson, Claes, Lorentzon, Mattias and Karlsson, Magnus K.. (2015). The number and characteristics of prevalent vertebral fractures in elderly men are associated with low bone mass and osteoporosis. The Bone and Joint Journal. 97-B(8), pp. 1106 - 1110. https://doi.org/10.1302/0301-620X.97B8.35032

Journal article

Changes in cortical volumetric bone mineral density and thickness, and trabecular thickness in lactating women postpartum
Brembeck, P., Lorentzon, Mattias, Ohlsson, Claes, Winkvist, A. and Augustin, H.. (2015). Changes in cortical volumetric bone mineral density and thickness, and trabecular thickness in lactating women postpartum. The Journal of Clinical Endocrinology and Metabolism. 100(2), pp. 535 - 543. https://doi.org/10.1210/jc.2014-2825

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Low clinical relevance of a prevalent vertebral fracture in elderly men - the MrOs Sweden study
Kherad, Mehrsa, Rosengren, Björn E., Hasserius, Ralph, Nilsson, Jan-Åke, Redlund-Johnell, Inga, Ohlsson, Claes, Lorentzon, Mattias, Mellström, Dan and Karlsson, Magnus K.. (2015). Low clinical relevance of a prevalent vertebral fracture in elderly men - the MrOs Sweden study. The Spine Journal. 15(2), pp. 281 - 289. https://doi.org/10.1016/j.spinee.2014.09.016

Journal article

Increased cortical porosity in older men with fracture
Sundh, Daniel, Mellström, Dan, Nilsson, Martin, Karlsson, Magnus, Ohlsson, Claes and Lorentzon, Mattias. (2015). Increased cortical porosity in older men with fracture. Journal of Bone and Mineral Research. 30(9), pp. 1692 - 1700. https://doi.org/10.1002/jbmr.2509

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Bone turnover markers predict bone mass development in young adult men: A five-year longitudinal study
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Kwan, Johnny S. H., Hsu, Yi-Hsiang, Cheung, Ching-Lung, Dupuis, Josée, Saint-Pierre, Aude, Eriksson, Joel, Handelman, Samuel K., Aragaki, Aaron K., Karasik, David, Pramstaller, Peter P., Kooperberg, Charles, Lacroix, Andrea Z., Larson, Martin G., Lau, Kam-Shing, Lorentzon, Mattias, Pichler, Irene, Sham, Pak Chung, Taliun, Daniel, Vandenput, Liesbeth, ... Kung, Annie Wai Chee. (2014). Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. Human Molecular Genetics. 23(24), pp. 6684 - 6693. https://doi.org/10.1093/hmg/ddu386

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Rudäng, Robert, Darelid, Anna, Nilsson, Martin, Mellström, Dan, Ohlsson, Claes and Lorentzon, Mattias. (2013). X-ray-verified fractures are associated with finite element analysis-derived bone strength and trabecular microstructure in young adult men. Journal of Bone and Mineral Research. 28(11), pp. 2305-2316. https://doi.org/10.1002/jbmr.1974

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Meta-analysis of gene-level associations for rare variants based on single-variant statistics
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Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density of forearm
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Inferior physical performance test results of 10,998 men in the MrOS Study is associated with high fracture risk
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Low serum vitamin D is associated with increased mortality in elderly men: MrOS Sweden
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Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
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Genetic determinants of serum testosterone concentrations in men
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Low bone mineral density is associated with increased mortality in elderly men: MrOS Sweden
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