Imre W. K. Kouw
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Research outputs
Stable isotope approaches to study muscle mass outcomes in clinical populations
Chapple, Lee-Anne S., Dirks, Marlou L. and Kouw, Imre W. K.. (2021). Stable isotope approaches to study muscle mass outcomes in clinical populations. Clinical Nutrition Open Science. 36, pp. 98-108. https://doi.org/10.1016/j.nutos.2021.01.004Journal article
No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males
Pinckaers, Philippe J. M., Kouw, Imre W. K., Hendriks, Floris K., van Kranenburg, Janneau M. X., de Groot, Lisette C. P. G. M., Verdijk, Lex B., Snijders, Tim and van Loon, Luc J. C.. (2021). No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males. British Journal of Nutrition. 126(12), pp. 1832-1842. https://doi.org/10.1017/S0007114521000635Journal article
Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest
Gonzalez, Javier T., Dirks, Marlou L., Holwerda, Andrew M., Kouw, Imre W. K. and van Loon, Luc J. C.. (2020). Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest. European Journal of Applied Physiology. 120, pp. 2083-2094. https://doi.org/10.1007/s00421-020-04431-4Journal article
During hospitalization, older patients at risk for malnutrition consume <0.65 grams of protein per kilogram body weight per day
Weijzen, Michelle E. G., Kouw, Imre W. K., Geerlings, Phil, Verdijk, Lex B. and van Loon, Luc J. C.. (2020). During hospitalization, older patients at risk for malnutrition consume <0.65 grams of protein per kilogram body weight per day. Nutrition in Clinical Practice. 35(4), pp. 655-663. https://doi.org/10.1002/ncp.10542Journal article
Protein type, protein dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in humans
Gorissen, Stefan H. M., Trommelen, Jorn, Kouw, Imre W. K., Holwerda, Andrew M., Pennings, Bart, Groen, Bart B. L., Wall, Benjamin T., Churchward-Venne, Tyler A., Horstman, Astrid M. H., Koopman, René, Burd, Nicholas A., Fuchs, Cas J., Dirks, Marlou L., Res, Peter T., Senden, Joan M. G., Steijns, Jan M. J. M., de Groot, Lisette C. P. G. M., Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Protein type, protein dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in humans. The Journal of Nutrition. 150(8), pp. 2041-2050. https://doi.org/10.1093/jn/nxaa024Journal article
Postexercise cooling impairs muscle protein synthesis rates in recreational athletes
Fuchs, Cas J., Kouw, Imre W. K., Churchward-Venne, Tyler A., Smeets, Joey S. J., Senden, Joan M., Lichtenbelt, Wouter D. van Marken, Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Postexercise cooling impairs muscle protein synthesis rates in recreational athletes. The Journal of Physiology. 598(4), pp. 755-772. https://doi.org/10.1113/JP278996Journal article
The muscle protein synthetic response to whey protein ingestion is greater in middle-aged women when compared with men
Horstman, Astrid M. H., Kouw, Imre W. K., van Dijk, Jan-Willem, Hamer, Henrike M., Groen, Bart B. L., van Kranenburg, Janneau, Gorissen, Stefan H. M. and van Loon, Luc J. C.. (2019). The muscle protein synthetic response to whey protein ingestion is greater in middle-aged women when compared with men. The Journal of Clinical Endocrinology and Metabolism. 104(4), pp. 994 - 1004. https://doi.org/10.1210/jc.2018-01734Journal article
The impact of pre-sleep protein ingestion on the skeletal muscle adaptive response to exercise in humans: An update
Snijders, Tim, Trommelen, Jorn, Kouw, Imre W. K., Holwerda, Andrew M., Verdijk, Lex B. and van Loon, Luc J. C.. (2019). The impact of pre-sleep protein ingestion on the skeletal muscle adaptive response to exercise in humans: An update. Frontiers in Nutrition. 6, pp. 1 - 8. https://doi.org/10.3389/fnut.2019.00017Journal article
Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest
Dirks, Marlou L., Smeets, Joey S. J., Holwerda, Andrew M., Kouw, Imre W. K., Marzuca-Nassr, Gabriel N., Gijsen, Annemie P., Holloway, Graham P., Verdijk, Lex B. and van Loon, Luc J. C.. (2019). Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest. American Journal of Physiology - Endocrinology and Metabolism. 316(3), pp. 536 - 545. https://doi.org/10.1152/ajpendo.00378.2018Journal article
Protein intake falls below 0.6 g.kg-1d-1 in healthy, older patients admitted for elective hip of knee arthroplasty
Weijzen, M. E. G., Kouw, Imre W. K., Verschuren, A. A. J., Muyters, R., Geurts, Jan A. P., Emans, P. J., Geerlings, P., Verdijk, Lex B. and Van Loon, Luc J. C.. (2019). Protein intake falls below 0.6 g.kg-1d-1 in healthy, older patients admitted for elective hip of knee arthroplasty. Journal of Nutrition, Health and Aging. 23(3), pp. 299 - 305. https://doi.org/10.1007/s12603-019-1157-2Journal article
One week of hospitalization following elective hip surgery induces substantial muscle atrophy in older patients
Kouw, Imre W. K., Groen, Bart B. L., Smeets, Joey S. J., Kramer, Irene Fleur, van Kranenburg, Janneau M. X., Nilwik, Rachél, Geurts, Jan A. P., ten Broeke, René H. M., Poeze, Martijn, van Loon, Luc J. C. and Verdijk, Lex B.. (2019). One week of hospitalization following elective hip surgery induces substantial muscle atrophy in older patients. Journal of the American Medical Directors Association (JAMDA): long-term care: management, applied research and clinical issues. 20(1), pp. 35 - 42. https://doi.org/10.1016/j.jamda.2018.06.018Journal article
Basal and postprandial myofibrillar protein synthesis rates do not differ between lean and obese middle-aged men
Kouw, Imre W. K., van Dijk, Jan Willem, Horstman, Astrid M. H., Kramer, Irene Fleur, Goessens, Joy P. B., van Dielen, Francois M. H., Verdijk, Lex B. and van Loon, Luc J. C.. (2019). Basal and postprandial myofibrillar protein synthesis rates do not differ between lean and obese middle-aged men. The Journal of Nutrition. 149(9), pp. 1533 - 1542. https://doi.org/10.1093/jn/nxz104Journal article
Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial
Kouw, Imre W.K., Holwerda, Andrew M., Trommelen, Jorn, Kramer, Irene Fleur, Bastiaanse, Jacqueline, Halson, Shona, Wodzig, Will K.W.H., Verdijk, Lex B. and Van Loon, Luc. (2017). Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial. The Journal of Nutrition. 147(12), pp. 2252 - 2261. https://doi.org/10.3945/jn.117.254532Journal article
Habituation to low or high protein intake does not modulate basal or postprandial muscle protein synthesis rates: a randomized trial
Gorissen, Stefan H.M., Horstman, Astrid M.H., Franssen, Rinske, Kouw, Imre W.K., Wall, Benjamin T., Burd, N., de Groot, Lisette C.P.G.M. and Loon, Luc Van. (2017). Habituation to low or high protein intake does not modulate basal or postprandial muscle protein synthesis rates: a randomized trial. American Journal of Clinical Nutrition. 105(2), pp. 332 - 342. https://doi.org/10.3945/ajcn.115.129924Journal article
Sodium nitrate ingestion increases skeletal muscle nitrate content in humans
Nyakayiru, Jean, Kouw, Imre W.K., Cermak, N, Senden, Joan M., Van Loon, Luc and Verdijk, Lex B.. (2017). Sodium nitrate ingestion increases skeletal muscle nitrate content in humans. Journal of Applied Physiology. 123(3), pp. 637 - 644. https://doi.org/10.1152/japplphysiol.01036.2016Journal article
Both basal and post-prandial muscle protein synthesis rates, following the ingestion of a leucine-enriched whey protein supplement, are not impaired in sarcopenic older males
Kramer, Irene Fleur, Verdijk, Lex B., Hamer, Henrike M., Verlaan, Sjors, Luiking, Yvette C., Kouw, Imre W. K., Senden, Joan M., van Kranenburg, Janneau, Gijsen, Annemarie P., Bierau, Jörgen, Poeze, Martijn and van Loon, Luc J. C.. (2016). Both basal and post-prandial muscle protein synthesis rates, following the ingestion of a leucine-enriched whey protein supplement, are not impaired in sarcopenic older males. Clinical Nutrition. 36, pp. 1440 - 1449. https://doi.org/10.1016/j.clnu.2016.09.023Journal article
Physical activity performed in the evening increases the overnight muscle protein synthetic response to presleep protein ingestion in older men
Holwerda, Andrew M., Kouw, Imre W. K., Trommelen, Jorn, Halson, Shona L., Wodzig, Will K. W. H., Verdijk, Lex B. and van Loon, Luc J. C.. (2016). Physical activity performed in the evening increases the overnight muscle protein synthetic response to presleep protein ingestion in older men. Journal of Nutrition. 146(7), pp. 1307 - 1314. https://doi.org/10.3945/jn.116.230086Journal article
Resistance exercise augments postprandial overnight muscle protein synthesis rates
Trommelen, Jorn, Holwerda, Andrew M., Kouw, Imre W. K., Langer, Henning, Halson, Shona L., Verdijk, Lex B. and van Loon, Luc J. C.. (2016). Resistance exercise augments postprandial overnight muscle protein synthesis rates. Medicine and Science in Sports and Exercise. 48(12), pp. 2517-2525. https://doi.org/10.1249/MSS.0000000000001045Journal article
Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction
Klinkenberg, Lieke J. J., Wildi, Karin, Van Der Linden, Noreen, Kouw, Imre W. K., Niens, Marijke, Twerenbold, Raphael, Gimenez, Maria Rubini, Puelacher, Christian, Neuhaus, Jean Daniel, Hillinger, Petra, Nestelberger, Thomas, Boeddinghaus, Jasper, Grimm, Karin, Sabti, Zaid, Bons, Judith A. P., Van Suijlen, Jeroen D. E., Tan, Frans E. S., Kate, Joop Ten, Bekers, Otto, ... Meex, Steven J. R.. (2016). Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction. Clinical Chemistry. 62(12), pp. 1602 - 1611. https://doi.org/10.1373/clinchem.2016.257485Journal article
Sodium nitrate co-ingestion with protein does not augment postprandial muscle protein synthesis rates in older, type 2 diabetes patients
Kouw, Imre W. K., Cermak, Naomi M., Burd, Nicholas A., Churchward-Venne, Tyler A., Senden, Joan M., Gijsen, Annemie P. and van Loon, Luc J. C.. (2016). Sodium nitrate co-ingestion with protein does not augment postprandial muscle protein synthesis rates in older, type 2 diabetes patients. American Journal of Physiology - Endocrinology and Metabolism. 311(2), pp. 325 - 334. https://doi.org/10.1152/ajpendo.00122.2016Journal article
Postprandial protein handling is not impaired in type 2 diabetes patients when compared with normoglycemic controls
Kouw, Imre W. K., Gorissen, Stefan H. M., Burd, Nicholas A., Cermak, Naomi M., Gijsen, Annemie P., van Kranenburg, Janneau and van Loon, Luc J. C.. (2015). Postprandial protein handling is not impaired in type 2 diabetes patients when compared with normoglycemic controls. The Journal of Clinical Endocrinology and Metabolism. 100(8), pp. 3103 - 3111. https://doi.org/10.1210/jc.2015-1234Journal article
A single dose of sodium nitrate does not improve oral glucose tolerance in patients with type 2 diabetes mellitus
Cermak, Naomi M., Hansen, Dominique, Kouw, Imre W. K., van Dijk, Jan-Willem, Blackwell, James R., Jones, Andrew M., Gibala, Martin J. and van Loon, Luc J. C.. (2015). A single dose of sodium nitrate does not improve oral glucose tolerance in patients with type 2 diabetes mellitus. Nutrition Research. 35(8), pp. 674 - 680. https://doi.org/10.1016/j.nutres.2015.05.017Journal article
Impact of the macronutrient composition of a nutritional supplement on muscle protein synthesis rates in older men: A randomized, double blind, controlled trial
Kramer, Irene Fleur, Verdijk, Lex B., Hamer, Henrike M., Verlaan, Sjors, Luiking, Yvette C., Kouw, Imre W. K., Senden, Joan M., van Kranenburg, Janneau, Gijsen, Annemie P., Poeze, Martijn and van Loon, Luc J. C.. (2015). Impact of the macronutrient composition of a nutritional supplement on muscle protein synthesis rates in older men: A randomized, double blind, controlled trial. The Journal of Clinical Endocrinology and Metabolism. 100(11), pp. 4124 - 4132. https://doi.org/10.1210/jc.2015-2352Journal article
The use of doubly labeled milk protein to measure postprandial muscle protein synthesis rates in vivo in humans
Burd, N., Cermak, N., Kouw, Imre W. K., Gorissen, Stefan H. M., Gijsen, Annemie P. and Van Loon, Luc. (2014). The use of doubly labeled milk protein to measure postprandial muscle protein synthesis rates in vivo in humans. Journal of Applied Physiology. 117(11), pp. 1363 - 1370. https://doi.org/10.1152/japplphysiol.00411.2014Journal article
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