Leonidas Karagounis


Contact categoryResearcher
Job title Professor of Research Translation and Enterprise
Research instituteMary MacKillop Institute for Health Research
Faculty of Health Sciences

Research outputs

Intermittent fasting, energy balance and associated health outcomes in adults : Study protocol for a randomised controlled trial
Templeman, Iain, Thompson, Dylan, Gonzalez, Javier T., Walhin, Jean-Philippe, Reeves, Sue, Rogers, Phoebe, Brunstrom, Jeffrey M., Karagounis, Leonidas, Tsintzas, Kostas and Betts, James A.. (2018). Intermittent fasting, energy balance and associated health outcomes in adults : Study protocol for a randomised controlled trial. Trials. 19(1), pp. 1-11. https://doi.org/10.1186/s13063-018-2451-8

Journal article

Skeletal muscle myostatin mRNA expression is upregulated in aged human adults with excess adiposity but is not associated with insulin resistance and ageing
Wilhelmsen, Andrew, Stephens, F, Bennett, Andrew J., Karagounis, Leonidas, Jones, Simon W. and Tsintzas, Kostas. (2023). Skeletal muscle myostatin mRNA expression is upregulated in aged human adults with excess adiposity but is not associated with insulin resistance and ageing. GeroScience. 46(2), pp. 2033-2049. https://doi.org/10.1007/s11357-023-00956-6

Journal article

A meta-analysis comparing the effectiveness of alternate day fasting, the 5:2 diet, and time-restricted eating for weight loss
Elortegui Pascual, Paloma, Rolands, Maryann R., Eldridge, Alison L., Kassis, Amira, Mainardi, Fabio, Lê, Kim-Anne, Karagounis, Leonidas G., Gut, Philipp and Varady, Krista A.. (2023). A meta-analysis comparing the effectiveness of alternate day fasting, the 5:2 diet, and time-restricted eating for weight loss. Obesity. 31(Supp. 1), pp. 9-21. https://doi.org/10.1002/oby.23568

Journal article

A randomized controlled clinical trial in healthy older adults to determine efficacy of glycine and n-acetylcysteine supplementation on glutathione redox status and oxidative damage
Lizzo, Giulia, Migliavacca, Eugenia, Lamers, Daniela, Frézal, Adrien, Corthesy, John, Vinyes-Parès, Gerard, Bosco, Nabil, Karagounis, Leonidas, Hövelmann, Ulrike, Heise, Tim, Von Eynatten, Maximilian and Gut, Philipp. (2022). A randomized controlled clinical trial in healthy older adults to determine efficacy of glycine and n-acetylcysteine supplementation on glutathione redox status and oxidative damage. Frontiers in Aging. 3, p. Article 852569. https://doi.org/10.3389/fragi.2022.852569

Journal article

Impact of moderate dietary protein restriction on glucose homeostasis in a model of estrogen deficiency
Fournier, Carole, Karagounis, Leonidas G., Sacco, Sandra M., Horcajada, Marie-Noelle, Decaens, Thomas, Offord, Elizabeth A., Bouzakri, Karim and Ammann, Patrick. (2022). Impact of moderate dietary protein restriction on glucose homeostasis in a model of estrogen deficiency. Journal of Nutritional Biochemistry. 102, p. Article 108952. https://doi.org/10.1016/j.jnutbio.2022.108952

Journal article

Low-grade systemic inflammation interferes with anabolic and catabolic characteristics of the aged human skeletal muscle
Draganidis, Dimitrios, Jamurtas, Athanasios Z., Chondrogianni, Niki, Mastorakos, Georgios, Jung, Tobias, Grune, Tilman, Papadopoulos, Constantinos, Papanikolaou, Konstantinos, Papassotiriou, Ioannis, Papaevgeniou, Nikoletta, Poulios, Athanasios, Batrakoulis, Alexios, Deli, Chariklia K., Georgakouli, Kalliopi, Chatzinikolaou, Athanasios, Karagounis, Leonidas G. and Fatouros, Ioannis G.. (2021). Low-grade systemic inflammation interferes with anabolic and catabolic characteristics of the aged human skeletal muscle. Oxidative Medicine and Cellular Longevity. 2021, p. Article 8376915. https://doi.org/10.1155/2021/8376915

Journal article

A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults
Templeman, Iain, Smith, Harry Alex, Chowdhury, Enhad, Chen, Yung-Chih, Carroll, Harriet, Johnson-Bonson, Drusus, Hengist, Aaron, Smith, Rowan, Creighton, Jade, Clayton, David, Varley, Ian, Karagounis, Leonidas Georgios, Wilhelmsen, Andrew, Tsintzas, Kostas, Reeves, Sue, Walhin, Jean-Philippe, Gonzalez, Javier T., Thompson, Dylan and Betts, James A.. (2021). A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults. Science Translational Medicine. 13(598), pp. 1-12. https://doi.org/10.1126/scitranslmed.abd8034

Journal article

Unacylated ghrelin, leptin, and appetite display diurnal rhythmicity in lean Adults
Templeman, Iain, Smith, Harry A., Walhin, Jean-Philippe, Middleton, Benita, Gonzalez, Javier T., Karagounis, Leonidas G., Johnston, Jonathan D. and Betts, James A.. (2021). Unacylated ghrelin, leptin, and appetite display diurnal rhythmicity in lean Adults. Journal of Applied Physiology. 130(5), pp. 1534-1543. https://doi.org/10.1152/japplphysiol.00920.2020

Journal article

Ingestion of a pre-bedtime protein containing beverage prevents overnight induced negative whole body protein balance in healthy middle-aged men : A randomized trial
Karagounis, Leonidas G., Beaumont, Maurice, Donato-Capel, Laurence, Godin, Jean-Philippe, Kapp, Anne-France, Draganidis, Dimitrios, Pinaud, Stéphane, Vuichoud, Jacques, Shevlyakova, Maya, Rade-Kukic, Koraljka and Breuillé, Denis. (2019). Ingestion of a pre-bedtime protein containing beverage prevents overnight induced negative whole body protein balance in healthy middle-aged men : A randomized trial. Frontiers in Nutrition. 6, p. Article 181. https://doi.org/10.3389/fnut.2019.00181

Journal article

Systemic and metabolic signature of sarcopenia in community-dwelling older adults
Lu, Yanxia, Karagounis, Leonidas G., Ng, Tze Pin, Carre, Christophe, Narang, Vipin, Wong, Glenn, Tan, Crystal Tze Ying, Nyunt, Ma Shwe Zin, Gao, Qi, Abel, Brian, Poidinger, Michael, Fulop, Tamas, Bosco, Nabil and Larbi, Anis. (2020). Systemic and metabolic signature of sarcopenia in community-dwelling older adults. Journals of Gerontology: Series A Biological Sciences and Medical Sciences. 75(2), pp. 309-317. https://doi.org/10.1093/gerona/glz001

Journal article

Chronotype : Implications for Epidemiologic Studies on Chrono-Nutrition and Cardiometabolic Health
Almoosawi, Suzana, Vingeliene, Snieguole, Gachon, Frédéric, Voortman, Trudy, Palla, Luigi, Johnston, Jonathan D., Van Dam, Rob, Darimont, Christian and Karagounis, Leonidas. (2019). Chronotype : Implications for Epidemiologic Studies on Chrono-Nutrition and Cardiometabolic Health. Advances in Nutrition. 10(1), pp. 30-42. https://doi.org/10.1093/advances/nmy070

Journal article

Longitudinal association of dietary protein intake in infancy and adiposity throughout childhood
Jen, Vincent, Braun, Kim V. E., Karagounis, Leonidas G., Nguyen, Anh N., Jaddoe, Vincent W. V., Schoufour, Josje D., Franco, Oscar H. and Voortman, Trudy. (2019). Longitudinal association of dietary protein intake in infancy and adiposity throughout childhood. Clinical Nutrition. 38(3), pp. 1296-1302. https://doi.org/10.1016/j.clnu.2018.05.013

Journal article

Dietary protein intake in school-age children and detailed measures of body composition : The Generation R Study
Jen, Vincent, Karagounis, Leonidas G., Jaddoe, Vincent W. V., Franco, Oscar H. and Voortman, Trudy. (2018). Dietary protein intake in school-age children and detailed measures of body composition : The Generation R Study. International Journal of Obesity. 42(10), pp. 1715-1723. https://doi.org/10.1038/s41366-018-0098-x

Journal article

Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation
Draganidis, Dimitrios, Jamurtas, A, Stampoulis, Theodoros, Laschou, Vasiliki C., Deli, Chariklia K., Georgakouli, Kalliopi, Papanikolaou, Konstantinos, Chatzinikolaou, A, Michalopoulou, Maria, Papadopoulos, Constantinos, Tsimeas, Panagiotis, Chondrogianni, Niki, Koutedakis, Yiannis, Karagounis, Leonidas and Fatouros, i. (2018). Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation. Nutrients. 10(5), p. Article 566. https://doi.org/10.3390/nu10050566

Journal article

Protein intake at breakfast promotes a positive whole-body protein balance in a dose-response manner in healthy children : A randomized trial
Karagounis, Leonidas G., Volterman, Kimberly A., Breuillé, Denis, Offord, Elizabeth A., Emady-Azar, Shahram and Moore, Daniel R.. (2018). Protein intake at breakfast promotes a positive whole-body protein balance in a dose-response manner in healthy children : A randomized trial. The Journal of Nutrition. 148(5), pp. 729-737. https://doi.org/10.1093/jn/nxy026

Journal article

Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle
Perrin, Laurent, Loizides-Mangold, Ursula, Chanon, Stéphanie, Gobet, Cédric, Hulo, Nicolas, Isenegger, Laura, Weger, Benjamin D., Migliavacca, Eugenia, Charpagne, Aline, Betts, James A., Walhin, Jean-Philippe, Templeman, Iain, Stokes, Keith A., Karagounis, Leonidas, Thompson, Dylan, Tsintzas, Kostas, Robert, Maud, Howald, Cedric, Riezman, Howard, ... Dibner, Charna. (2018). Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle. eLife. 7, pp. 1-30. https://doi.org/10.7554/eLife.34114

Journal article

Post-game high protein intake may improve recovery of football-specific performance during a congested game fixture : Results from the PRO-FOOTBALL study
Poulios, Athanasios, Fatouros, Ioannis G., Mohr, Magni, Draganidis, Dimitrios, Deli, Chariklia K., Papanikolaou, Konstantinos, Sovatzidis, Apostolos, Nakopoulou, Theofano, Ermidis, Georgios, Tzatzakis, Theofanis, Laschou, Vasiliki C., Georgakouli, Kalliopi, Koulouris, Agisilaos, Tsimeas, Panagiotis, Chatzinikolaou, Athanasios, Karagounis, Leonidas G., Batsilas, Dimitrios, Krustrup, Peter and Jamurtas, Athanasios Z.. (2018). Post-game high protein intake may improve recovery of football-specific performance during a congested game fixture : Results from the PRO-FOOTBALL study. Nutrients. 10(4), p. Article 494. https://doi.org/10.3390/nu10040494

Journal article

Protein ingestion preserves proteasome activity during intense aseptic inflammation and facilitates skeletal muscle recovery in humans
Draganidis, Dimitrios, Chondrogianni, Niki, Chatzinikolaou, Athanasios, Terzis, Gerasimos, Karagounis, Leonidas G., Sovatzidis, Apostolos, Avloniti, Alexandra, Lefaki, Maria, Protopapa, Maria, Deli, Chariklia K., Papanikolaou, Konstantinos, Jamurtas, Athanasios Z. and Fatouros, Ioannis G.. (2017). Protein ingestion preserves proteasome activity during intense aseptic inflammation and facilitates skeletal muscle recovery in humans. British Journal of Nutrition. 118(3), pp. 189-200. https://doi.org/10.1017/S0007114517001829

Journal article

Timing and pattern of postexercise protein ingestion affects whole-body protein balance in healthy children : A randomized trial
Volterman, Kimberly A., Moore, Daniel R., Breithaupt, Peter, Grathwohl, Dominik, Offord, Elizabeth A., Karagounis, Leonidas G. and Timmons, Brian W.. (2017). Timing and pattern of postexercise protein ingestion affects whole-body protein balance in healthy children : A randomized trial. Applied Physiology, Nutrition and Metabolism. 42(11), pp. 1142-1148. https://doi.org/10.1139/apnm-2017-0185

Journal article

Amino acid composition of breast milk from urban Chinese mothers
Garcia-Rodenas, Clara L., Affolter, Michael, Vinyes-Parès, Gerard, De Castro, Carlos A., Karagounis, Leonidas G., Zhang, Yumei, Wang, Peiyu and Thakkar, Sagar K.. (2016). Amino acid composition of breast milk from urban Chinese mothers. Nutrients. 8(10), p. Article 606. https://doi.org/10.3390/nu8100606

Journal article

Inflammaging and skeletal muscle : Can protein intake make a difference?
Draganidis, Dimitrios, Karagounis, Leonidas G., Athanailidis, Ioannis, Chatzinikolaou, Athanasios, Jamurtas, Athanasios Z. and Fatouros, Ioannis G.. (2016). Inflammaging and skeletal muscle : Can protein intake make a difference? The Journal of Nutrition. 146(10), pp. 1940-1952. https://doi.org/10.3945/jn.116.230912

Journal article

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