Abualnaja, SerajPodder, MohuaHernandez, Adrian F.McMurray, John J.V.Starling, Randall C.O'Connor, Christopher M.Califf, Robert M.Armstrong, Paul W.Ezekowitz, Justin A.2025-10-1720152047-998010.1161/JAHA.115.002092https://hdl.handle.net/20.500.14802/32124Background-—Patients with acute heart failure (AHF) frequently have atrial fibrillation (AF), but how this affects patient-reported outcomes has not been well characterized. Methods and Results-—We examined dyspnea improvement and clinical outcomes in 7007 patients in the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) trial. At baseline, 2677 (38.2%) patients had current or a history of AF and 4330 (61.8%) did not. Patients with a history of AF were older than those without (72 vs. 63 years) and had more comorbidities and a higher median left ventricular ejection fraction (31% vs. 27%, Pacute heart failureatrial fibrillationclinical trialsoutcomeJournal article2-s2.0-85016925384Published as ‘gold’ (paid) open accessControlled201046658