All rights reservedRalph, NicholasNg, Shu KayZajdlewicz, LeahLepore, Stephen J.Heathcote, PeterKneebone, AndrewDunn, Jeffrey C.Chambers, Suzanne K.2025-10-1720202021-11-241057-924910.1002/pon.5255https://hdl.handle.net/20.500.14802/32825Key points: • Many prostate cancer survivors face ongoing decrements in health-related quality of life (HRQoL) • The long-term trajectories of men with prostate cancer are not well described • To our knowledge, this is the first substantive prospective study to track men's HRQoL, life satisfaction and symptom burden ten years from diagnosis • Androgen deprivation therapy (ADT), multiple comorbidities, younger age and socioeconomic disadvantage are risk indicators for poorer long-term HRQoL after prostate cancer. • Risk indicators need to be incorporated into survivorship care planning to facilitate personalised care for men most at risk of poorer physical and mental health.mental healthprostatic neoplasmspsychological symptomsprostate cancerquality of lifesurvivorssurvivorshipsupportive careJournal article2-s2.0-85075376684ControlledPUB0201084738NHMRC/442301