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Alcohol ingestion impairs maximal post-exercise rates of myofibrillar protein synthesis following a single bout of concurrent training
Parr, Evelyn Camera, Donny Areta, José Burke, Louise Phillips, Stuart Hawley, John A. Coffey, Vernon
Parr, Evelyn
Camera, Donny
Areta, José
Burke, Louise
Phillips, Stuart
Hawley, John A.
Coffey, Vernon
Abstract
Introduction
The culture in many team sports involves consumption of large amounts of alcohol after training/competition. The effect of such a practice on recovery processes underlying protein turnover in human skeletal muscle are unknown. We determined the effect of alcohol intake on rates of myofibrillar protein synthesis (MPS) following strenuous exercise with carbohydrate (CHO) or protein ingestion. Methods
In a randomized cross-over design, 8 physically active males completed three experimental trials comprising resistance exercise (8×5 reps leg extension, 80% 1 repetition maximum) followed by continuous (30 min, 63% peak power output (PPO)) and high intensity interval (10×30 s, 110% PPO) cycling. Immediately, and 4 h post-exercise, subjects consumed either 500 mL of whey protein (25 g; PRO), alcohol (1.5 g·kg body mass−1, 12±2 standard drinks) co-ingested with protein (ALC-PRO), or an energy-matched quantity of carbohydrate also with alcohol (25 g maltodextrin; ALC-CHO). Subjects also consumed a CHO meal (1.5 g CHO·kg body mass−1) 2 h post-exercise. Muscle biopsies were taken at rest, 2 and 8 h post-exercise. Results
Blood alcohol concentration was elevated above baseline with ALC-CHO and ALC-PRO throughout recovery (P Conclusion
We provide novel data demonstrating that alcohol consumption reduces rates of MPS following a bout of concurrent exercise, even when co-ingested with protein. We conclude that alcohol ingestion suppresses the anabolic response in skeletal muscle and may therefore impair recovery and adaptation to training and/or subsequent performance.
Keywords
Date
2014
Type
Journal article
Journal
PLoS ONE
Book
Volume
9
Issue
2
Page Range
1-9
Article Number
ACU Department
Centre for Exercise and Nutrition
Faculty of Health Sciences
Non-faculty
Mary MacKillop Institute for Health Research
Faculty of Health Sciences
Non-faculty
Mary MacKillop Institute for Health Research
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Relation URI
Source URL
Event URL
Open Access Status
Open access
License
File Access
Controlled
Notes
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.