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Origin of cardiac Troponin T Elevations in chronic kidney disease
van der Linden, Noreen Cornelis, Tom Kimenai, Dorien M. Klinkenberg, Lieke J. J. Hilderink, Judith M. Lück, Sarah Litjens, Elisabeth J. R. Peeters, Frederique E. C. M. Streng, Alexander S. Breidthardt, Tobias
van der Linden, Noreen
Cornelis, Tom
Kimenai, Dorien M.
Klinkenberg, Lieke J. J.
Hilderink, Judith M.
Lück, Sarah
Litjens, Elisabeth J. R.
Peeters, Frederique E. C. M.
Streng, Alexander S.
Breidthardt, Tobias
Author
van der Linden, Noreen
Cornelis, Tom
Kimenai, Dorien M.
Klinkenberg, Lieke J. J.
Hilderink, Judith M.
Lück, Sarah
Litjens, Elisabeth J. R.
Peeters, Frederique E. C. M.
Streng, Alexander S.
Breidthardt, Tobias
van Loon, Luc J. C.
Bekers, Otto
Kooman, Jeroen P.
Westermark, Pål O.
Mueller, Christian
Meex, Steven J. R.
Cornelis, Tom
Kimenai, Dorien M.
Klinkenberg, Lieke J. J.
Hilderink, Judith M.
Lück, Sarah
Litjens, Elisabeth J. R.
Peeters, Frederique E. C. M.
Streng, Alexander S.
Breidthardt, Tobias
van Loon, Luc J. C.
Bekers, Otto
Kooman, Jeroen P.
Westermark, Pål O.
Mueller, Christian
Meex, Steven J. R.
Abstract
[Extract] Plasma concentrations of cardiac troponins, the preferred biomarkers for the diagnosis of acute myocardial infarction, are often persistently elevated in patients with chronic kidney disease (CKD). The origin of these elevations is unknown: Is it the heart, by increased release, or the kidneys, by decreased renal elimination? In clinical practice, this equivocal view on troponin elevations in patients with reduced glomerular clearance underlies countless clinical discussions among physicians and may delay rapid initiation of adequate treatment when these patients present with chest pain.
Keywords
kidney diseases, troponin
Date
2017
Type
Journal article
Journal
Circulation
Book
Volume
136
Issue
11
Page Range
1073-1075
Article Number
ACU Department
Collections
Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled