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Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for Stroke prevention in atrial fibrillation
Wallentin, Lars ; Lopes, Renato D. ; Hanna, Michael ; Thomas, Laine ; Hellkamp, Anne ; Nepal, Sunil ; Hylek, Elaine ; Al-Khatib, Sana M. ; Alexander, John H. ; Alings, Marco ... show 10 more
Wallentin, Lars
Lopes, Renato D.
Hanna, Michael
Thomas, Laine
Hellkamp, Anne
Nepal, Sunil
Hylek, Elaine
Al-Khatib, Sana M.
Alexander, John H.
Alings, Marco
Author
Wallentin, Lars
Lopes, Renato D.
Hanna, Michael
Thomas, Laine
Hellkamp, Anne
Nepal, Sunil
Hylek, Elaine
Al-Khatib, Sana M.
Alexander, John H.
Alings, Marco
Amerena, John
Ansell, Jack
Aylward, Philip
Bartunek, Jozef
Commerford, Patrick
De Caterina, Raffaele
Erol, Çetin
Harjola, Veli-Pekka
Held, Claes
Horowitz, John
Huber, Kurt
Husted, Steen
Keltai, Matyas
Lanas, Fernando
Lisheng, Liu
McMurray, John
Oh, Byung Hee
Rosenqvist, Mårten
Ruzyllo, Witold
Steg, Philippe Gabriel
Vinereanu, Dragos
Xavier, Denis
Granger, Christopher B.
Lopes, Renato D.
Hanna, Michael
Thomas, Laine
Hellkamp, Anne
Nepal, Sunil
Hylek, Elaine
Al-Khatib, Sana M.
Alexander, John H.
Alings, Marco
Amerena, John
Ansell, Jack
Aylward, Philip
Bartunek, Jozef
Commerford, Patrick
De Caterina, Raffaele
Erol, Çetin
Harjola, Veli-Pekka
Held, Claes
Horowitz, John
Huber, Kurt
Husted, Steen
Keltai, Matyas
Lanas, Fernando
Lisheng, Liu
McMurray, John
Oh, Byung Hee
Rosenqvist, Mårten
Ruzyllo, Witold
Steg, Philippe Gabriel
Vinereanu, Dragos
Xavier, Denis
Granger, Christopher B.
Abstract
In the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial, apixaban compared with warfarin reduced stroke and systemic embolism, major bleeding, and mortality. We evaluated treatment effects in relation to 2 predictions of time in therapeutic range (TTR).
Keywords
anticoagulation, apixaban, atrial fibrillation, bleeding, stroke, warfarin
Date
2013
Type
Journal article
Journal
Circulation
Book
Volume
127
Issue
22
Page Range
2166-2176
Article Number
ACU Department
Collections
Relation URI
Source URL
Event URL
Open Access Status
Open access
License
File Access
Controlled
