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Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for Stroke prevention in atrial fibrillation

Wallentin, Lars
Lopes, Renato D.
Hanna, Michael
Thomas, Laine
Hellkamp, Anne
Nepal, Sunil
Hylek, Elaine
Al-Khatib, Sana M.
Alexander, John H.
Alings, Marco
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Abstract
In the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial, apixaban compared with warfarin reduced stroke and systemic embolism, major bleeding, and mortality. We evaluated treatment effects in relation to 2 predictions of time in therapeutic range (TTR).
Keywords
anticoagulation, apixaban, atrial fibrillation, bleeding, stroke, warfarin
Date
2013
Type
Journal article
Journal
Circulation
Book
Volume
127
Issue
22
Page Range
2166-2176
Article Number
ACU Department
Relation URI
Source URL
Event URL
Open Access Status
Open access
License
File Access
Controlled
Notes