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Genetics of dementia : A focus on Alzheimer's disease
Fernandez, Francesca Andrews, Jessica L.
Fernandez, Francesca
Andrews, Jessica L.
Abstract
This chapter focuses on providing a brief overview of genes associated with sporadic (late-onset) Alzheimer's disease (AD). Despite decades of research, no current and reliable test is currently available for the diagnosis of AD. Genetic biomarkers are promising for both diagnostic tools and tailored profiling therapy. Genes associated with sporadic AD through linkage, association, and genome-wide association case studies are briefly described. We also discuss the genes underlying cognitive function in the context of AD.
Keywords
cognitive dysfunction, genetic biomarkers cognitive related genes, genetic risk factors, late-onset, Alzheimer's disease
Date
2020
Type
Book chapter
Journal
Book
The neuroscience of dementia ; volume 1
Volume
Issue
Page Range
127-146
Article Number
ACU Department
School of Behavioural and Health Sciences
Faculty of Health Sciences
Faculty of Health Sciences
Relation URI
Source URL
Event URL
Open Access Status
License
All rights reserved
File Access
Controlled