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Transient endothelial dysfunction induced by sugar-sweetened beverage consumption may be attenuated by a single bout of aerobic exercise
Varsamis, Pia Walr, Guillaume Share, Bianca Taylor, Frances Stewart, Simon Lorenzen, Christian Loader, Jordan
Varsamis, Pia
Walr, Guillaume
Share, Bianca
Taylor, Frances
Stewart, Simon
Lorenzen, Christian
Loader, Jordan
Abstract
Background: This study assessed whether aerobic exercise would attenuate microvascular endothelial dysfunction induced by commercial sugar-sweetened beverage (SSB) consumption. Methods: Eleven healthy males participated in this randomized, single-blind crossover study. Cutaneous microvascular endothelial function was assessed using laser speckle contrast imaging coupled with post-occlusive reactive hyperemia before and after a)consumption of water; b) consumption of a commercial SSB; c) 30 min of aerobic exercise followed by water consumption; and d) 30 minutes of aerobic exercise followed by SSB consumption. Blood glucose and arterial pressure responses were also monitored. Volumes of water and SSB consumed (637.39 ± 29.15 mL) were individualized for each participant, ensuring SSB consumption delivered 1 g of sucrose per kg of body weight. Exercise was performed at 75% of the maximal oxygen uptake heart rate. Results: Compared to water consumption, the commercial SSB elevated blood glucose concentrations in both sedentary (4.69 ± 0.11 vs. 7.47 ± 0.28 mmol/L, P < 0.05) and exercised states (4.95 ± 0.13 vs. 7.93 ± 0.15 mmol/L, P < 0.05). However, the decrease in microvascular endothelial function observed following sedentary SSB consumption, expressed as the percentage increase from baseline (208.60 ± 22.40 vs. 179.83 ± 15.80%, P = 0.01) and the change in peak hyperemic blood flux from basal to post-intervention assessments (− 0.04 ± 0.03 vs. − 0.12 ± 0.02 ΔCVC, P = 0.01), was attenuated following 30 min of aerobic exercise. Conclusions: To our knowledge, this is the first study to provide evidence that a single bout of aerobic exercise may prevent transient SSB-mediated microvascular endothelial dysfunction.
Keywords
sugar-sweetened beverages, acute hyperglycemia, endothelial dysfunction, microcirculation, aerobic exercise
Date
2018
Type
Journal article
Journal
Microvascular Research
Book
Volume
115
Issue
Page Range
8-11
Article Number
ACU Department
School of Behavioural and Health Sciences
Faculty of Health Sciences
Centre for Education and Innovation
Faculty of Health Sciences
Centre for Education and Innovation
Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled