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The effect of progressive resistance exercise on knee muscle strength and function in participants with persistent hamstring deficit following ACL reconstruction : A randomized controlled trial

Bregenhof, Bo
Aagaard, Per
Nissen, Nis
Creaby, Mark W.
Thorlund, Jonas Bloch
Jensen, Carsten
Torfing, Trine
Holsgaard-Larsen, Anders
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Abstract
OBJECTIVE: To investigate the effect of progressive resistance exercise compared with low-intensity home-based exercises on knee-muscle strength and joint function in people with anterior cruciate ligament (ACL) reconstruction and persistent hamstring strength deficits at 12–24 months after surgery. DESIGN: Randomized controlled superiority trial with parallel groups, balanced randomization (1:1), and blinded outcome assessment. METHODS: People with ACL reconstruction (hamstring autograft) and persistent hamstring muscle strength asymmetry were recruited 1 to 2 years postsurgery and randomized to either 12 weeks of supervised progressive strength training (SNG), or 12 weeks of home-based, low-intensity exercises (CON). The primary outcome was between-group difference in change in maximal isometric knee flexor muscle strength at 12-week follow-up. RESULTS: Fifty-one participants (45% women, 27 ± 6 years) were randomized to SNG (n = 25) or CON (n = 26), with 88% follow-up rate at 12 weeks. People in the SNG group improved their knee flexor muscle strength (0.18 N·m/kg, 95% confidence interval [CI]: 0.07, 0.29; P = .002) more than the CON group, from baseline to 12 weeks. The SNG group also had superior Knee Injury and Osteoarthritis Outcome Scores for Pain (4.6, 95% CI: 0.4, 8.7; P = .031) and daily living function (4.7, 95% CI: 1.2, 8.2; P = .010) compared to the CON group. CONCLUSION: In people with persistent hamstring muscle strength deficits after ACL reconstruction, 12 weeks of supervised progressive strength training was superior to low-intensity home-based exercises for improving maximal knee flexor muscle strength and some patient-reported outcomes. J Orthop Sports Phys Ther 2023;53(1):40–48. Epub: 17 October 2022. doi:10.2519/jospt.2022.11360
Keywords
anterior cruciate, ligament reconstruction, functional outcome, hamstring, muscle strength, rehabilitation
Date
2023
Type
Journal article
Journal
Journal of Orthopaedic and Sports Physical Therapy
Book
Volume
53
Issue
1
Page Range
40-48
Article Number
ACU Department
School of Behavioural and Health Sciences
Faculty of Health Sciences
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Open Access Status
License
All rights reserved
File Access
Controlled
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