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Toward earlier identification and preventative intervention in schizophrenia: evidence from the London Child Health and Development Study
Laurens, Kristin Cullen, Alexis E.
Laurens, Kristin
Cullen, Alexis E.
Abstract
Purpose The London Child Health and Development Study (CHADS) is a prospective, longitudinal investigation of children, sampled from the general community aged 9–11 years and assessed biennially, who present premorbid risk markers for schizophrenia. The study aims to characterise developmental trajectories of psychological, cognitive, and biological functioning in at-risk children and identify potential targets for early preventative intervention. This review summarises CHADS findings, discusses these in the context of recent theory regarding aetiology and prevention of schizophrenia, and highlights challenges to be addressed with future research.
Keywords
psychosis, high-risk, developmental psychopathology, psychotic-like experiences, adolescence
Date
2016
Type
Journal article
Journal
Social Psychiatry and Psychiatric Epidemiology
Book
Volume
51
Issue
4
Page Range
475-491
Article Number
ACU Department
Relation URI
Source URL
Event URL
Open Access Status
Open access
License
CC BY 4.0
File Access
Open