Synchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cells

Journal article

Sheridan, Erin J., Austin, Christopher J. D., Aitken, Jade B., Vogt, Stefan, Jolliffe, Katrina A., Harris, Hugh H. and Rendina, Louis M.. (2013). Synchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cells. Journal of Synchrotron Radiation. 20(2), pp. 226 - 233. https://doi.org/10.1107/S0909049513001647
AuthorsSheridan, Erin J., Austin, Christopher J. D., Aitken, Jade B., Vogt, Stefan, Jolliffe, Katrina A., Harris, Hugh H. and Rendina, Louis M.
Abstract

The first example of synchrotron X-ray fluorescence imaging of cultured mammalian cells in cyclic peptide research is reported. The study reports the first quantitative analysis of the incorporation of a bromine-labelled cyclic RGD peptide and its effects on the biodistribution of endogenous elements (for example, K and Cl) within individual tumor cells.

KeywordsXRF; microprobe; RGD peptide; tumor cells
Year2013
JournalJournal of Synchrotron Radiation
Journal citation20 (2), pp. 226 - 233
PublisherWiley-Blackwell
ISSN0909-0495
Digital Object Identifier (DOI)https://doi.org/10.1107/S0909049513001647
Scopus EID2-s2.0-84874079317
Open accessOpen access
Page range226 - 233
Research GroupSchool of Behavioural and Health Sciences
Publisher's version
License
Place of publicationUnited Kingdom
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