Jejunal feeding is followed by a greater rise in plasma cholecystokinin, peptide YY, glucagon-like peptide 1, and glucagon-like peptide 2 concentrations compared with gastric feeding in vivo in humans: a randomized trial

Journal article

Luttikhold, Joanna, van Norren, Klaske, Rijna, Herman, Buijs, Nikki, Ankersmit, Marjolein, Heijboer, Annemieke C., Gootjes, Jeannette, Hartmann, Bolette, Holst, Jens J., Van Loon, Lucas J. C. and van Leeuwen, Paul A. M.. (2016). Jejunal feeding is followed by a greater rise in plasma cholecystokinin, peptide YY, glucagon-like peptide 1, and glucagon-like peptide 2 concentrations compared with gastric feeding in vivo in humans: a randomized trial. American Journal of Clinical Nutrition. 103(2), pp. 435 - 443. https://doi.org/10.3945/ajcn.115.116251
AuthorsLuttikhold, Joanna, van Norren, Klaske, Rijna, Herman, Buijs, Nikki, Ankersmit, Marjolein, Heijboer, Annemieke C., Gootjes, Jeannette, Hartmann, Bolette, Holst, Jens J., Van Loon, Lucas J. C. and van Leeuwen, Paul A. M.
Abstract

Jejunal feeding is preferred instead of gastric feeding in patients who are intolerant to gastric feeding or at risk of aspiration. However, the impact of gastric feeding compared with that of jejunal feeding on postprandial circulating plasma glucose and amino acid concentrations and the associated endocrine response in vivo in humans remains largely unexplored. We compared the impact of administering enteral nutrition as either gastric feeding or jejunal feeding on endocrine responses in vivo in humans.

Keywordsenteral nutrition; gastric feeding; gastrointestinal hormones; jejunal feeding; malnutrition
Year2016
JournalAmerican Journal of Clinical Nutrition
Journal citation103 (2), pp. 435 - 443
PublisherAmerican Society for Nutrition
ISSN0002-9165
Digital Object Identifier (DOI)https://doi.org/10.3945/ajcn.115.116251
Scopus EID2-s2.0-84956897867
Page range435 - 443
Research GroupMary MacKillop Institute for Health Research
Publisher's version
File Access Level
Controlled
Place of publicationUnited States of America
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