Improved cognitive performance after dietary supplementation with a Pinus radiata bark extract formulation

Journal article


Pipingas, Andrew, Silberstein, Richard, Vitetta, Luis, Van Rooy, Cindy, Harris, Elizabeth, Young, Joanna, Frampton, Christopher, Sali, Avni and Nastasi, Joseph. (2008). Improved cognitive performance after dietary supplementation with a Pinus radiata bark extract formulation. Phytotherapy Research: an international journal devoted to medical and scientific research on plants and plant products. 22(9), pp. 1168 - 1174. https://doi.org/10.1002/ptr.2388
AuthorsPipingas, Andrew, Silberstein, Richard, Vitetta, Luis, Van Rooy, Cindy, Harris, Elizabeth, Young, Joanna, Frampton, Christopher, Sali, Avni and Nastasi, Joseph
Abstract

Dietary interventions may have the potential to counter age-related cognitive decline. Studies have demonstrated an improvement in age-related cognitive impairment in animals after supplementation with plant extracts containing flavonoids but there are few human studies. This double-blind, controlled study examined the effects on cognitive performance of a 5 week supplementation with Enzogenol®Pinus radiata bark extract containing flavonoids, in 42 males aged 50–65 years, with a body mass index > 25. Participants were supplemented for 5 weeks either with Enzogenol® plus vitamin C, or with vitamin C only. A battery of computerized cognitive tests was administered, and cardiovascular and haematological parameters were assessed prior to and following supplementation. The speed of response for the spatial working memory and immediate recognition tasks improved after supplementation with Enzogenol®plus vitamin C, whereas vitamin C alone showed no improvements. A trend in a reduction of systolic blood pressure was observed with Enzogenol® plus vitamin C, but not with vitamin C alone. The blood safety parameters were unchanged. The findings suggest a beneficial effect of supplementation with Enzogenol® on cognition in older individuals. Larger studies are needed to ascertain its potential as a preventive treatment for age-related cognitive decline.

Year2008
JournalPhytotherapy Research: an international journal devoted to medical and scientific research on plants and plant products
Journal citation22 (9), pp. 1168 - 1174
ISSN0951-418X
Digital Object Identifier (DOI)https://doi.org/10.1002/ptr.2388
Page range1168 - 1174
Publisher's version
File Access Level
Controlled
Permalink -

https://acuresearchbank.acu.edu.au/item/88y26/improved-cognitive-performance-after-dietary-supplementation-with-a-pinus-radiata-bark-extract-formulation

Restricted files

Publisher's version

  • 94
    total views
  • 0
    total downloads
  • 1
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

No effect of multivitamin supplementation on central blood pressure in healthy older people: A randomized controlled trial
Harris, Elizabeth Valentine, Rowsell, Renee, Pipingas, Andrew and Macpherson, Helen. (2016). No effect of multivitamin supplementation on central blood pressure in healthy older people: A randomized controlled trial. Atherosclerosis. 246, pp. 236 - 242. https://doi.org/10.1016/j.atherosclerosis.2016.01.030
Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults
Harris, Elizabeth, Macpherson, Helen and Pipingas, Andrew. (2015). Improved blood biomarkers but no cognitive effects from 16 weeks of multivitamin supplementation in healthy older adults. Nutrients. 17(5), pp. 3796 - 3812. https://doi.org/10.3390/nu7053796
Blood pressure and cognitive function : The role of central aortic and brachial pressures
Pase, Matthew, Stough, Con, Grima, Natalie, Harris, Elizabeth, Macpherson, Helen, Scholey, Andrew and Pipingas, Andrew. (2013). Blood pressure and cognitive function : The role of central aortic and brachial pressures. Psychological Science. 24(11), pp. 2173 - 2181. https://doi.org/10.1177/0956797613488602
Effects of a multivitamin, mineral and herbal supplement on cognition and blood biomarkers in older men: A randomised, placebo-controlled trial
Harris, Elizabeth Valentine, Macpherson, Helen, Vitetta, Luis, Kirk, Joni, Sali, Avni and Pipingas, Andrew. (2012). Effects of a multivitamin, mineral and herbal supplement on cognition and blood biomarkers in older men: A randomised, placebo-controlled trial. Human Psychopharmacology. 27(4), pp. 370 - 377. https://doi.org/10.1002/hup.2236
Assessing the efficacy of nutraceutical interventions on cognitive functioning in the elderly
Pipingas, Andrew, Harris, Elizabeth, Tournier, Elesha, King, Rebecca, Kras, Marni and Stough, Con K.. (2012). Assessing the efficacy of nutraceutical interventions on cognitive functioning in the elderly. Current Topics in Nutraceutical Research. 8(2/3), pp. 79 - 88.
The effect of multivitamin supplementation on mood and stress in healthy older men
Harris, Elizabeth, Kirk, Joni, Rowsell, Renee, Vitetta, Luis, Sali, Avni, Scholey, Andrew and Pipingas, Andrew. (2011). The effect of multivitamin supplementation on mood and stress in healthy older men. Human Psychopharmacology: Clinical and Experimental. 26(8), pp. 560 - 567. https://doi.org/10.1002/hup.1245
Improved cognitive performance after dietary supplementation with a Pinus radiata bark extract formulation
Pipingas, Andrew, Silberstein, Richard, Vitetta, Luis, Van Rooy, Cindy, Harris, Elizabeth Valentine, Young, Joanna, Frampton, Christopher, Sali, Avni and Nastasi, Joseph. (2008). Improved cognitive performance after dietary supplementation with a Pinus radiata bark extract formulation. Phytotherapy Research: an international journal devoted to medical and scientific research on plants and plant products. 22(9), pp. 1168 - 1174. https://doi.org/10.1002/ptr.2388
Utilisation of general practitioner services by socio-economic disadvantage and geographic remoteness
Turrell, Gavin, Oldenburg, Brian, Harris, Elizabeth and Jolley, Damien. (2004). Utilisation of general practitioner services by socio-economic disadvantage and geographic remoteness. Australian and New Zealand Journal of Public Health. 28(2), pp. 152 - 158. https://doi.org/10.1111/j.1467-842X.2004.tb00929.x