High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis

Journal article

Weston, Kassia S., Wisloff, Ulrik and Coombes, Jeff S.. (2014). High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. British Journal of Sports Medicine. 48(16), pp. 1227 - 1234. https://doi.org/10.1136/bjsports-2013-092576
AuthorsWeston, Kassia S., Wisloff, Ulrik and Coombes, Jeff S.

Background/Aim Cardiorespiratory fitness (CRF) is a strong determinant of morbidity and mortality. In athletes and the general population, it is established that high-intensity interval training (HIIT) is superior to moderate-intensity continuous training (MICT) in improving CRF. This is a systematic review and metaanalysis to quantify the efficacy and safety of HIIT compared to MICT in individuals with chronic cardiometabolic lifestyle diseases. Methods The included studies were required to have a population sample of chronic disease, where poor lifestyle is considered as a main contributor to the disease. The procedural quality of the studies was assessed by use of a modified Physiotherapy Evidence Base Database (PEDro) scale. A meta-analysis compared the mean difference (MD) of preintervention versus postintervention CRF (VO2peak) between HIIT and MICT. Results 10 studies with 273 patients were included in the meta-analysis. Participants had coronary artery disease, heart failure, hypertension, metabolic syndrome and obesity. There was a significantly higher increase in the VO2peak after HIIT compared to MICT (MD 3.03 mL/kg/ min, 95% CI 2.00 to 4.07), equivalent to 9.1%. Conclusions HIIT significantly increases CRF by almost double that of MICT in patients with lifestyle-induced chronic diseases.

JournalBritish Journal of Sports Medicine
Journal citation48 (16), pp. 1227 - 1234
Digital Object Identifier (DOI)https://doi.org/10.1136/bjsports-2013-092576
Scopus EID2-s2.0-84905506043
Page range1227 - 1234
Research GroupSports Performance, Recovery, Injury and New Technologies (SPRINT) Research Centre
Publisher's version
File Access Level
Place of publicationUnited Kingdom
EditorsK. Khan
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