A comparison of the effects of aerobic and intense exercise on the type 2 diabetes mellitus risk marker adipokines, adiponectin and retinol binding protein-4

Journal article


Phillips, Amy and Cobbold, Christian. (2014). A comparison of the effects of aerobic and intense exercise on the type 2 diabetes mellitus risk marker adipokines, adiponectin and retinol binding protein-4. International Journal of Chronic Diseases. 2014, pp. 1 - 5. https://doi.org/10.1155/2014/358058
AuthorsPhillips, Amy and Cobbold, Christian
Abstract

With a more sedentary population comes growing rates of obesity and increased type 2 diabetes mellitus (T2DM) risk. Exercise generally induces positive changes in traditional T2DM risk markers such as lipids, glucose tolerance, and insulin sensitivity; however alterations in concentrations of many circulating cytokines and their respective receptors are also becoming apparent. These cytokines may be early-response health risk factors otherwise overlooked in traditional T2DM risk marker analysis. Plasma levels of two adipocyte-originating cytokines, adiponectin and retinol binding protein 4 (RBP-4), alter following exercise. Adiponectin has anti-inflammatory, anti-atherosclerotic, and anti-insulin resistance roles and its secretion increases with physical activity, whilst elevated RBP-4 leads to increased insulin resistance, and secretion decreases with increasing physical activity; thus these plasma adipokine levels alter favourably following exercise. Although current data are limited, they do suggest that the more intense the exercise, the greater the positive effect on plasma RBP-4 levels, whilst lower intensity aerobic exercise may positively improve adiponectin concentrations. Therefore short-duration, high intensity training may provide a time-efficient alternative to the recommended 150 min moderate aerobic exercise per week in providing positive changes in RBP-4 and other traditional T2DM risk markers and due to increased compliance give greater health benefits over the longer term.

Year2014
JournalInternational Journal of Chronic Diseases
Journal citation2014, pp. 1 - 5
PublisherHindawi Publishing Corporation
ISSN2356-6981
Digital Object Identifier (DOI)https://doi.org/10.1155/2014/358058
Open accessOpen access
Page range1 - 5
Research GroupSchool of Behavioural and Health Sciences
Publisher's version
License
Place of publicationUnited States of America
Permalink -

https://acuresearchbank.acu.edu.au/item/89y55/a-comparison-of-the-effects-of-aerobic-and-intense-exercise-on-the-type-2-diabetes-mellitus-risk-marker-adipokines-adiponectin-and-retinol-binding-protein-4

Download files


Publisher's version
  • 47
    total views
  • 94
    total downloads
  • 0
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Type 2 diabetes mellitus risk and exercise: Is resistin involved?
Cobbold, Christian. (2019). Type 2 diabetes mellitus risk and exercise: Is resistin involved? The Journal of Sports Medicine and Physical Fitness. 59(2), pp. 290 - 297. https://doi.org/10.23736/S0022-4707.18.08258-0
Battle of the sexes: Which is better for you, high- or low-intensity exercise?
Christian Cobbold. (2018). Battle of the sexes: Which is better for you, high- or low-intensity exercise? Journal of Sport and Health Science. 7(4), pp. 429-432. https://doi.org/10.1016/j.jshs.2018.05.004
The effect of creatine supplementation on body composition and bone health in the elderly
Moon, Anna and Cobbold, Christian. (2016). The effect of creatine supplementation on body composition and bone health in the elderly. Journal of Obesity & Weight Loss Therapy. 6(1), pp. 1 - 5. https://doi.org/10.4172/2165-7904.1000298
Creatine supplementation in the elderly: Is resistance training really needed?
Moon, Anna, Heywood, Lara, Rutherford, Stephen and Cobbold, Christian. (2015). Creatine supplementation in the elderly: Is resistance training really needed? Journal of Nutrition and Health Sciences. 2(2), pp. 1 - 9. https://doi.org/10.15744/2393-9060.2.203
Heterogeneous responses of personalised high intensity interval training on type 2 diabetes mellitus and cardiovascular disease risk in young healthy adults
Higgins, Timothy, Baker, Matthew, Evans, Shelley-Ann, Adams, Rachel and Cobbold, Christian. (2015). Heterogeneous responses of personalised high intensity interval training on type 2 diabetes mellitus and cardiovascular disease risk in young healthy adults. Clinical Hemorheology and Microcirculation. 59(4), pp. 365 - 377. https://doi.org/10.3233/CH-141857
The effect of angiotensin converting enzyme genotype on aerobic capacity following high intensity interval training
Goddard, Nicole, Baker, Matthew, Higgins, Tim and Cobbold, Christian. (2014). The effect of angiotensin converting enzyme genotype on aerobic capacity following high intensity interval training. International Journal of Exercise Science. 7(3), pp. 250 - 259.