Oxidative stress in surgery

Book chapter


Rosenfeldt, Franklin, Wilson, Mark, Lee, Geraldine, Kure, Christina, Ou, Ruchong, Braun, Lesley and de Haan, Judy. (2014). Oxidative stress in surgery. In Systems biology of free radicals and antioxidants pp. 3929-3946 Springer-Verlag. https://doi.org/10.1007/978-3-642-30018-9_177
AuthorsRosenfeldt, Franklin, Wilson, Mark, Lee, Geraldine, Kure, Christina, Ou, Ruchong, Braun, Lesley and de Haan, Judy
Abstract

Reactive oxygen species (ROS) play both physiological and pathophysiological roles in the body. In clinical practice, oxidative stress and its counterpart, antioxidant capacity, can be measured and can guide remedial therapy. Oxidative stress can make a negative impact in all forms of major surgery including cardiac surgery, general surgery, trauma surgery, orthopedic surgery, and plastic surgery. Many and various therapies aimed at reducing oxidative stress in surgery have been tried with variable results. We conclude that in surgical patients, the assessment of oxidative stress, improving understanding of its role, both positive and negative, and devising appropriate therapies are of great clinical importance and represent fruitful fields for further research.

Keywordsantioxidant capacity; free radicals; oxidative stress; reactive oxygen species; surgery
Page range3929-3946
Year2014
Book titleSystems biology of free radicals and antioxidants
PublisherSpringer-Verlag
Place of publicationBerlin, Germany
Heidelberg, Germany
ISBN9783642300172
9783642300189
Digital Object Identifier (DOI)https://doi.org/10.1007/978-3-642-30018-9_177
Scopus EID2-s2.0-8492913837
Research GroupSchool of Nursing, Midwifery and Paramedicine
Output statusPublished
Publication dates
Online03 May 2014
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