Pulmonary hypertension in low- and middle-income countries with focus on sub-Saharan Africa
Journal article
Anastase Dzudie, Bonaventure Suiru Dzekem, Dike B. Ojji, Andre Pascal Kengne, Ana Olga Mocumbi, Karen Sliwa and Friedrich Thienemann. (2020). Pulmonary hypertension in low- and middle-income countries with focus on sub-Saharan Africa. Cardiovascular Diagnosis & Therapy. 10(2), pp. 316-324. https://doi.org/10.21037/cdt.2019.07.06
Authors | Anastase Dzudie, Bonaventure Suiru Dzekem, Dike B. Ojji, Andre Pascal Kengne, Ana Olga Mocumbi, Karen Sliwa and Friedrich Thienemann |
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Abstract | Pulmonary hypertension (PH) is a devastating, progressive disease with increasingly debilitating symptoms and usually shortened overall life expectancy. This article reviews the global epidemiology of PH with focus on low- and middle-income countries (LMICs) and sub-Sahara African in particular. Although left ventricular heart disease is the most common cause globally, the main contributing risk factors in LMICs are chronic infectious diseases especially human immunodeficiency virus (HIV) and schistosomiasis. Other important risk factors of PH are rheumatic heart disease, untreated congenital heart disease (CHD), and sickle cell disease. Despite existing epidemiological data of PH risk factors suggesting a high prevalence in sub-Saharan Africa (SSA), the available literature is limited. International registries in LMICs like the pan African pulmonary hypertension cohort (PAPUCO) study are essential to provide information about the causes, treatment, outcome, and the natural course of PH in Africa and other parts of the world. In addition, there is a need to track diagnostic and management practices in order to develop suitable algorithms to diagnose PH in LMICs. |
Keywords | pulmonary hypertension (PH); epidemiology; Africa; low- and middle-income countries (LMICs) |
Year | 2020 |
Journal | Cardiovascular Diagnosis & Therapy |
Journal citation | 10 (2), pp. 316-324 |
Publisher | AME Publishing Company |
ISSN | 2223-3652 |
Digital Object Identifier (DOI) | https://doi.org/10.21037/cdt.2019.07.06 |
Scopus EID | 2-s2.0-85085591925 |
Open access | Published as ‘gold’ (paid) open access |
Publisher's version | License File Access Level Open |
Publication process dates | |
Deposited | 30 Apr 2021 |
https://acuresearchbank.acu.edu.au/item/8vyxw/pulmonary-hypertension-in-low-and-middle-income-countries-with-focus-on-sub-saharan-africa
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Publisher's version
OA_Dzudie_2020_Pulmonary_hypertension_in_low_and_middle.pdf | |
License: CC BY-NC-ND 4.0 | |
File access level: Open |
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