Predictors of anxiety in multiple sclerosis
Journal article
Hartoonian, Narineh, Terrill, Alexandra L., Beier, Meghan L., Turner, Aaron P. and Day, Melissa A.. (2015). Predictors of anxiety in multiple sclerosis. Rehabilitation Psychology. 60(1), pp. 91-98. https://doi.org/10.1037/rep0000019
Authors | Hartoonian, Narineh, Terrill, Alexandra L., Beier, Meghan L., Turner, Aaron P. and Day, Melissa A. |
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Abstract | Purpose/Objectives: The aims of this study were to (1) identify the predictors of symptoms of anxiety, and (2) evaluate the differential association of somatic and nonsomatic symptoms of depression on anxiety over time in persons with multiple sclerosis (MS). Method/Design: Participants were 513 persons with MS who previously enrolled in a study exploring the experience of living with MS and completed a 4-month follow-up survey. The main outcome measure used was the Hospital Anxiety and Depression Scale–Anxiety. Demographic, disease-associated variables (time since onset of MS, Expanded Disability Status Scale Mobility, pain, and fatigue), and Time 1 psychological variables were entered into a hierarchical regression model to examine predictors at baseline for anxiety symptoms at Time 2. Results: A large portion of the sample was White (92%), female (82%), and had relapsing-remitting MS (57%). After adjusting for demographic and disease related variables, anxiety (β <.001), employment (β = .07), and nonsomatic depressive symptoms (β = .10) at baseline significantly predicted anxiety at Time 2, ps < .05. Interactions revealed significant effects for time since onset of MS and somatic symptoms as well as time since onset and nonsomatic symptoms, ps < .05. Nonsomatic symptoms were more linked to anxiety early in the disease and somatic symptoms were more prominently linked to anxiety later in the disease. Conclusions: Findings suggest that nonsomatic symptoms of depression and employment predict anxiety in MS. The relationship between different aspects of depression and anxiety may change over the course of the disease. (PsycINFO Database Record (c) 2016 APA, all rights reserved) |
Keywords | multiple sclerosis; anxiety; depression |
Year | 2015 |
Journal | Rehabilitation Psychology |
Journal citation | 60 (1), pp. 91-98 |
Publisher | American Psychological Association |
ISSN | 0090-5550 |
Digital Object Identifier (DOI) | https://doi.org/10.1037/rep0000019 |
PubMed ID | 25496434 |
Scopus EID | 2-s2.0-84925758433 |
PubMed Central ID | PMC4339307 |
Open access | Published as green open access |
Page range | 91-98 |
Funder | National Institute on Disability and Rehabilitation Research (NIDRR), National Institutes of Health |
Department of Education, United States of America | |
National Institutes of Health (NIH), United States of America | |
National Multiple Sclerosis Society Grant | |
Author's accepted manuscript | License All rights reserved File Access Level Open |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 15 Dec 2014 |
Publication process dates | |
Accepted | 23 Oct 2014 |
Deposited | 02 Nov 2022 |
Grant ID | H133B031129 |
H133B080025 | |
5U01AR052171–03 | |
MB0008 | |
MB0026 |
https://acuresearchbank.acu.edu.au/item/8y688/predictors-of-anxiety-in-multiple-sclerosis
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Author's accepted manuscript
AM_Hartoonian_2015_Predictors_of_anxiety_in_Multiple_Sclerosis.pdf | |
License: All rights reserved | |
File access level: Open |
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