Women's decision making about risk-reducing strategies in the context of hereditary breast and ovarian cancer: A systematic review
Journal article
Howard, A., Balneaves, Lynda G. and Bottorff, Joan Lorraine. (2009). Women's decision making about risk-reducing strategies in the context of hereditary breast and ovarian cancer: A systematic review. Journal of Genetic Counseling. 18(6), pp. 578 - 597. https://doi.org/10.1007/s10897-009-9245-9
Authors | Howard, A., Balneaves, Lynda G. and Bottorff, Joan Lorraine |
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Abstract | Women who have a mutation in the BRCA1 or BRCA2 genes have up to an 87% lifetime risk of breast cancer and up to a 40% lifetime risk of ovarian cancer. Cancer prevention and early detection strategies are often considered by these women to address this heightened risk. Risk-reducing strategies include risk-reducing mastectomy and oophorectomy, breast and ovarian cancer screening, and chemoprevention. This systematic literature review summarizes the factors and contexts that influence decision making related to cancer risk-reducing strategies among women at high-risk for hereditary breast and ovarian cancer. In the 43 published research articles reviewed, three main types of factors are identified that influence high-risk women’s decisions about risk-reducing strategies: a) medical and physical factors, b) psychological factors and c) social context factors. How these factors operate in women’s lives over time remains unknown, and would best be elucidated through prospective, longitudinal research, as well as qualitative research. |
Keywords | brca1; brca2; screening; risk-reducing mastectomy; risk-reducing oophorectomy; chemoprevention; risk reduction; decision making |
Year | 2009 |
Journal | Journal of Genetic Counseling |
Journal citation | 18 (6), pp. 578 - 597 |
Publisher | Springer |
ISSN | 1059-7700 |
Digital Object Identifier (DOI) | https://doi.org/10.1007/s10897-009-9245-9 |
Page range | 578 - 597 |
Place of publication | United States of America |
https://acuresearchbank.acu.edu.au/item/8934v/women-s-decision-making-about-risk-reducing-strategies-in-the-context-of-hereditary-breast-and-ovarian-cancer-a-systematic-review
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