Microbiome Changes in Humans with Parkinson’s Disease after Photobiomodulation Therapy : A Retrospective Study

Journal article

Bicknell, Brian, Liebert, Ann, Mclachlan, Craig and Kiat, Hosen. (2022). Microbiome Changes in Humans with Parkinson’s Disease after Photobiomodulation Therapy : A Retrospective Study. Journal of Personalized Medicine. 12(1), pp. 1-15. https://doi.org/10.3390/jpm12010049
AuthorsBicknell, Brian, Liebert, Ann, Mclachlan, Craig and Kiat, Hosen
Abstract

There is a paucity of information on the effect of photobiomodulation therapy on gut microbiome composition. Parkinson’s disease is a progressive neurological disorder with few management options, although the gut microbiome has been suggested as a potential avenue of treatment. We retrospectively analysed the microbiome from human stool samples from a previously published study, which had demonstrated the efficacy of photobiomodulation to treat Parkinson’s patients’ symptoms. Specifically, we have observed changes in the microbiome of Parkinson’s patients after a 12-week treatment regimen with photobiomodulation to the abdomen, neck, head and nose. Noted were positive changes in the Firmicutes to Bacteroidetes (F:B) ratio, which is often interpreted as a proxy for gut health.

Keywordsmicrobiome; Parkinson’s disease; photobiomodulation
Year01 Jan 2022
JournalJournal of Personalized Medicine
Journal citation12 (1), pp. 1-15
PublisherMDPI AG
ISSN2075-4426
Digital Object Identifier (DOI)https://doi.org/10.3390/jpm12010049
Web address (URL)https://www.mdpi.com/2075-4426/12/1/49
Open accessPublished as ‘gold’ (paid) open access
Research or scholarlyResearch
Page range1-15
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Print01 Jan 2022
Publication process dates
Accepted29 Dec 2021
Deposited17 Feb 2025
Additional information

© 2022 by the authors. Licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Place of publicationSwitzerland
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