Intrathecal baclofen therapy in children : An analysis of individualized goals

Journal article


Liew, Peck Yee, Stewart, Kirsty, Khan, Debra, Arnup, Sarah Jane and Scheinberg, Adam. (2018). Intrathecal baclofen therapy in children : An analysis of individualized goals. 60(4), pp. 367-373. https://doi.org/10.1111/dmcn.13660
AuthorsLiew, Peck Yee, Stewart, Kirsty, Khan, Debra, Arnup, Sarah Jane and Scheinberg, Adam
Abstract

Aim
To determine whether intrathecal baclofen (ITB) therapy improves performance and performance satisfaction in goal areas identified by patients' parents.

Method
This study formed part of an ongoing multicentre national audit involving six paediatric ITB pump implant centres across Australia. The Canadian Occupational Performance Measure was the primary outcome measure utilized at baseline, 6 months, and 12 months after pump implants in paediatric patients receiving ITB therapy for the first time between 31st December 2009 and 31st December 2014.

Results
Twenty-five children had goals identified (mean age 11y 1mo), 19 had a diagnosis of cerebral palsy and 22 were at Gross Motor Function Classification System level IV, V, or equivalent. Strong evidence for an improvement in goal performance (2.33, 95% CI 1.70, 2.96, p<0.001) and performance satisfaction scores (3.08, 95% CI 2.28, 3.88, p<0.001) were demonstrated at 6 months, compared to baseline. The differences were clinically significant and were sustained to 12 months.

Interpretation
ITB therapy in paediatric patients with hypertonia results in clinically significant improvements in average performance and performance satisfaction scores.

What this paper adds
The most commonly identified goals of parents of children treated with intrathecal (ITB) therapy were: improving ease of dressing, positioning, and transfers.
ITB therapy is effective in improving performance and performance satisfaction in children with hypertonia.
Score improvements are mainly evident within the first 6 months of therapy.

Year2018
Journal citation60 (4), pp. 367-373
PublisherBlackwell Publishing Ltd
ISSN0012-1622
Digital Object Identifier (DOI)https://doi.org/10.1111/dmcn.13660
Scopus EID2-s2.0-85044394651
Research or scholarlyResearch
Page range367-373
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online19 Jan 2018
Publication process dates
Accepted27 Nov 2017
Deposited15 Jul 2021
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https://acuresearchbank.acu.edu.au/item/8w5z5/intrathecal-baclofen-therapy-in-children-an-analysis-of-individualized-goals

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