State of the Evidence Traffic Lights 2019 : Systematic review of interventions for preventing and treating children with cerebral palsy

Journal article


Novak, Iona, Morgan, Catherine, Fahey, Michael, Finch-Edmondson, Megan, Galea, Claire, Hines, Ashleigh, Langdon, Katherine, Namara, Maria Mc, Paton, Madison C. B., Popat, Himanshu, Shore, Benjamin, Khamis, Amanda, Stanton, Emma, Finemore, Olivia P., Tricks, Alice, te Velde, Anna, Dark, Leigha, Morton, Natalie and Badawi, Nadia. (2020). State of the Evidence Traffic Lights 2019 : Systematic review of interventions for preventing and treating children with cerebral palsy. Current Neurology and Neuroscience Reports. 20(3), pp. 1-21. https://doi.org/10.1007/s11910-020-1022-z
AuthorsNovak, Iona, Morgan, Catherine, Fahey, Michael, Finch-Edmondson, Megan, Galea, Claire, Hines, Ashleigh, Langdon, Katherine, Namara, Maria Mc, Paton, Madison C. B., Popat, Himanshu, Shore, Benjamin, Khamis, Amanda, Stanton, Emma, Finemore, Olivia P., Tricks, Alice, te Velde, Anna, Dark, Leigha, Morton, Natalie and Badawi, Nadia
Abstract

Purpose of Review
Cerebral palsy is the most common physical disability of childhood, but the rate is falling, and severity is lessening. We conducted a systematic overview of best available evidence (2012–2019), appraising evidence using GRADE and the Evidence Alert Traffic Light System and then aggregated the new findings with our previous 2013 findings. This article summarizes the best available evidence interventions for preventing and managing cerebral palsy in 2019.

Recent Findings
Effective prevention strategies include antenatal corticosteroids, magnesium sulfate, caffeine, and neonatal hypothermia. Effective allied health interventions include acceptance and commitment therapy, action observations, bimanual training, casting, constraint-induced movement therapy, environmental enrichment, fitness training, goal-directed training, hippotherapy, home programs, literacy interventions, mobility training, oral sensorimotor, oral sensorimotor plus electrical stimulation, pressure care, stepping stones triple P, strength training, task-specific training, treadmill training, partial body weight support treadmill training, and weight-bearing. Effective medical and surgical interventions include anti-convulsants, bisphosphonates, botulinum toxin, botulinum toxin plus occupational therapy, botulinum toxin plus casting, diazepam, dentistry, hip surveillance, intrathecal baclofen, scoliosis correction, selective dorsal rhizotomy, and umbilical cord blood cell therapy.

Summary
We have provided guidance about what works and what does not to inform decision-making, and highlighted areas for more research.

Keywordscerebral palsy; systematic review; traffic light system; evidence based; GRADE
Year2020
JournalCurrent Neurology and Neuroscience Reports
Journal citation20 (3), pp. 1-21
PublisherSpringer
ISSN1528-4042
Digital Object Identifier (DOI)https://doi.org/10.1007/s11910-020-1022-z
Scopus EID2-s2.0-85079818791
Open accessPublished as ‘gold’ (paid) open access
Research or scholarlyResearch
Page range1-21
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online21 Feb 2020
Publication process dates
Deposited18 Aug 2021
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